Research map: Interleukins and Cardiovascular Disease

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Papers in this map

  1. Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease · Antonio Abbate · 2020 · 748 citations · Cited by this paper
  2. Exosome Therapy: A Novel Investigational Approach in Acute Myocardial Infarction · 2026 · Related
  3. IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial · Paul M. Ridker · 2021 · 736 citations · Cited by this paper
  4. Phenotype-dependent effects of IL-17A inhibitors on lipid profiles in moderate-to-severe plaque psoriasis: a retrospective cohort study · 2026 · Related
  5. Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis · Stephen K. Kaptoge · 2013 · 675 citations · Cited by this paper
  6. IL-2/IL-2Ab complexes expand regulatory T cells in vivo and provide neuroprotection after cardiac arrest · 2025 · Related
  7. The Effect of the Mediterranean Diet on Metabolic Health: A Systematic Review and Meta-Analysis of Controlled Trials in Adults · Angeliki Papadaki · 2020 · 264 citations · Cited by this paper
  8. Lipoprotein(a), interleukin-6 and cardiovascular risk in a primary prevention setting · 2026 · Related
  9. Inhibition of Interleukin-1β and Reduction in Atherothrombotic Cardiovascular Events in the CANTOS Trial · Brendan M. Everett · 2020 · 220 citations · Cited by this paper
  10. Mast cells as pivotal players in atherogenesis. Review · 2025 · Related
  11. From RESCUE to ZEUS: will interleukin-6 inhibition with ziltivekimab prove effective for cardiovascular event reduction? · Paul M. Ridker · 2021 · 157 citations · Cited by this paper
  12. Exercise-induced cardioprotection: From endogenous to exogenous mechanisms · 2025 · Related
  13. IL-32–dependent effects of IL-1β on endothelial cell functions · Claudia A. Nold‐Petry · 2009 · 144 citations · Cited by this paper
  14. Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy · 2026 · Related
  15. Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension · German Esteban Gonzalez · 2014 · 112 citations · Cited by this paper
  16. IL6/IL10/TLR4 Govern Immunogenic Cell Death in Aortic Dissection · 2026 · Related
  17. Elevated serum interleukin-6 is predictive of coronary artery disease in intermediate risk overweight patients referred for coronary angiography · Marco Vugman Wainstein · 2017 · 106 citations · Cited by this paper
  18. Modulation of myocardial injury in polymicrobial sepsis: The dual role of interleukin-13 in cardiac inflammation and stress · 2024 · Related
  19. Comparison of circulating levels of interleukin-6 and tumor necrosis factor-alpha in hypertrophic cardiomyopathy and in idiopathic dilated cardiomyopathy · M Högye · 2004 · 91 citations · Cited by this paper
  20. Interleukin-6-Mediated-Ca2+ Handling Abnormalities Contributes to Atrial Fibrillation in Sterile Pericarditis Rats · Jie Liao · 2021 · 71 citations · Cited by this paper
  21. Interleukin-6 and Cardiovascular Events in Healthy Adults · Muhammad Shahzeb Khan · 2024 · 67 citations · Cited by this paper
  22. Analysis of Circulating Apoptosis Mediators and Proinflammatory Cytokines in Patients With Idiopathic Hypertrophic Cardiomyopathy Comparison Between Nonobstructive and Dilated-Phase Hypertrophic Cardiomyopathy · Kan Zen · 2005 · 59 citations · Cited by this paper
  23. The pleiotropic role of interleukin-17 in atherosclerosis · Gamal A. Allam · 2018 · 56 citations · Cited by this paper
  24. Towards a role of interleukin-32 in atherosclerosis · Bas Heinhuis · 2013 · 50 citations · Cited by this paper
  25. Winter Swimming: Body Hardening and Cardiorespiratory Protection Via Sustainable Acclimation · Antonis S. Manolis · 2019 · 46 citations · Cited by this paper
  26. Mast cells: a novel therapeutic avenue for cardiovascular diseases? · Remo Poto · 2024 · 46 citations · Cited by this paper
  27. Sustained Pericarditis Recurrence Risk Reduction With Long‐Term Rilonacept · Massimo Imazio · 2024 · 44 citations · Cited by this paper
  28. Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression · Jong Ho Park · 2024 · 44 citations · Cited by this paper
  29. Mast Cells Control the Expansion and Differentiation of IL-10–Competent B Cells · Francesca Mion · 2014 · 43 citations · Cited by this paper
  30. Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3 · Erlinda The · 2022 · 42 citations · Cited by this paper
  31. The role of immunoglobulin E and mast cells in hypertension · Weipeng Ge · 2022 · 40 citations · Cited by this paper
  32. Targeting Inflammatory Pathways in Atherosclerosis: Exploring New Opportunities for Treatment · Alessia d’Aiello · 2024 · 40 citations · Cited by this paper
  33. Sacubitril-valsartan improves conduit vessel function and functional capacity and reduces inflammation in heart failure with reduced ejection fraction · Kanokwan Bunsawat · 2020 · 34 citations · Cited by this paper
  34. Inflammasome Signaling in Cardiac Arrhythmias: Linking Inflammation, Fibrosis, and Electrical Remodeling · Paschalis Karakasis · 2025 · 33 citations · Cited by this paper
  35. Rhodiola crenulata reduces ventricular arrhythmia through mitigating the activation of IL-17 and inhibiting the MAPK signaling pathway · Ya-Wen Hsiao · 2020 · 32 citations · Cited by this paper
  36. IL-17 as a therapeutic target in cardiovascular diseases: Mechanistic insights and translational opportunities · Lianyue Ma · 2025 · 29 citations · Cited by this paper
  37. Activated Mast Cells Mediate Low-Grade Inflammation in Type 2 Diabetes: Interleukin-37 Could Be Beneficial · Pio Conti · 2018 · 28 citations · Cited by this paper
  38. Exercise and Arrhythmias: A Double‐Edged Sword · Antonis S. Manolis · 2016 · 27 citations · Cited by this paper
  39. Interleukin-32 increases in coronary arteries and plasma from patients with coronary artery disease · Zicong Yang · 2019 · 27 citations · Cited by this paper

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