Research map: PSMA-Targeting SPECTTracer with Positively ChargedMercaptoacetyl-Based Chelator: Preclinical Evaluation and ExploratoryClinical Study

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  1. Prostate-specific Membrane Antigen Heterogeneity and DNA Repair Defects in Prostate Cancer · Alec Paschalis · 2019 · 478 citations · Cited by this paper
  2. Cross-Modality DeepLearning Denoising for Low-DoseμSPECT: Transfer of PET-Trained U-Net and Diffusion Models · 2026 · Related
  3. Heterogeneity of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Carcinoma with Distant Metastasis · Sebastian Mannweiler · 2008 · 390 citations · Cited by this paper
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  7. 99mTc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen: Pharmacokinetics and Biodistribution Studies in Healthy Subjects and Patients with Metastatic Prostate Cancer · Shankar Vallabhajosula · 2014 · 145 citations · Cited by this paper
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  11. 99mTc‐MIP‐1404‐SPECT/CT for the detection of PSMA‐positive lesions in 225 patients with biochemical recurrence of prostate cancer · Christian Schmidkonz · 2017 · 101 citations · Cited by this paper
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  13. European Study of Prostate Cancer Screening — 23-Year Follow-up · Monique J. Roobol · 2025 · 95 citations · Cited by this paper
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  15. Effect of molecular charges on renal uptake of 111 In-DTPA-conjugated peptides · Hiromichi Akizawa · 2001 · 92 citations · Cited by this paper
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  17. Influence of Labelling Methods on Biodistribution and Imaging Properties of Radiolabelled Peptides for Visualisation of Molecular Therapeutic Targets · Vladimir Tolmachev · 2010 · 84 citations · Cited by this paper
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  19. Influence of Different Spacers on the Biological Profile of a DOTA−Somatostatin Analogue · Patricia Antunes · 2006 · 77 citations · Cited by this paper
  20. Phase 2 Study of 99mTc-Trofolastat SPECT/CT to Identify and Localize Prostate Cancer in Intermediate- and High-Risk Patients Undergoing Radical Prostatectomy and Extended Pelvic LN Dissection · Karolien E. Goffin · 2017 · 76 citations · Cited by this paper
  21. New Radionuclides and Technological Advances in SPECT and PET Scanners · Nicholas Philip van der Meulen · 2021 · 56 citations · Cited by this paper
  22. Robot-assisted prostate-specific membrane antigen-radioguided surgery in primary diagnosed prostate cancer · William Gondoputro · 2022 · 54 citations · Cited by this paper
  23. Intrapatient Comparison of 111In-PSMA I&T SPECT/CT and Hybrid 68Ga-HBED-CC PSMA PET in Patients With Early Recurrent Prostate Cancer · Isabel Rauscher · 2016 · 53 citations · Cited by this paper
  24. Effects of Lysine-Containing Mercaptoacetyl-Based Chelators on the Biodistribution of 99mTc-Labeled Anti-HER2 Affibody Molecules · Thuy A. Tran · 2008 · 50 citations · Cited by this paper
  25. Kit formulation for 99mTc-labeling of recombinant anti-HER2 Affibody molecules with a C-terminally engineered cysteine · Sara Ahlgren · 2010 · 47 citations · Cited by this paper
  26. Evaluation of 99m Tc-labeled PSMA-SPECT/CT imaging in prostate cancer patients who have undergone biochemical relapse · Ding-Wei Ye · 2016 · 42 citations · Cited by this paper
  27. Radiation dosimetry of [68Ga]PSMA-11 in low-risk prostate cancer patients · Kristina Sandgren · 2019 · 42 citations · Cited by this paper
  28. 99mTc-labeled PSMA inhibitor: Biokinetics and radiation dosimetry in healthy subjects and imaging of prostate cancer tumors in patients · Clara Santos‐Cuevas · 2017 · 34 citations · Cited by this paper
  29. Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands · Fanny Lundmark · 2022 · 34 citations · Cited by this paper
  30. Evaluation of Radiation dosimetry of 99mTc-HYNIC-PSMA and imaging in prostate cancer · Jianping Zhang · 2020 · 31 citations · Cited by this paper
  31. Radiation Dosimetry of 99mTc-PSMA I&S: A Single-Center Prospective Study · Szabolcs Urbán · 2020 · 29 citations · Cited by this paper
  32. Preparation and clinical translation of 99m Tc-PSMA-11 for SPECT imaging of prostate cancer · Kusum Vats · 2019 · 21 citations · Cited by this paper
  33. Eligibility for 177 Lu-PSMA Therapy Depends on the Choice of Companion Diagnostic Tracer: A Comparison of 68 Ga-PSMA-11 and 99m Tc-MIP-1404 in Metastatic Castration-Resistant Prostate Cancer · Gary Cook · 2022 · 21 citations · Cited by this paper
  34. Diagnostic efficacy of [99mTc]Tc-PSMA SPECT/CT for prostate cancer: a meta-analysis · Qi Wang · 2024 · 21 citations · Cited by this paper
  35. A Systematic Investigation into the Influence of Net Charge on the Biological Distribution of Radiometalated Peptides Using [68Ga]Ga-DOTA-TATE Derivatives · Shvan J. Raheem · 2023 · 18 citations · Cited by this paper
  36. Synthesis and Preclinical Evaluation of Urea-Based Prostate-Specific Membrane Antigen-Targeted Conjugates Labeled with 177Lu · Aleksei E. Machulkin · 2024 · 16 citations · Cited by this paper
  37. An Australian experience using Tc‐PSMA SPECT/CT in the primary diagnosis of prostate cancer and for staging at biochemical recurrence after local therapy · Iain Duncan · 2023 · 15 citations · Cited by this paper
  38. PSMA PET/CT imaging and its application to prostate cancer treatment · Tomoaki Otani · 2024 · 15 citations · Cited by this paper
  39. Estimating the Absorbed Dose of Organs in Pediatric Imaging of 99mTc-DTPA Radiopharmaceutical using MIRDOSE Software · K. Ebrahimnejad Gorji · 2019 · 12 citations · Cited by this paper

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