Research map: Cognition endpoints for Parkinson's disease: A roadmap for developing patient-focused assessment tools to accelerate drug development

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Papers in this map

  1. Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines · Irene Litvan · 2012 · 2585 citations · Cited by this paper
  2. Integrating a biopsychosocial perspective: WHODAS 2.0 enhances functioning assessment in Parkinson's disease · 2026 · Related
  3. Parkinson disease-associated cognitive impairment · Dag Aarsland · 2021 · 1421 citations · Cited by this paper
  4. A case of monotherapy with intracerebroventricular anaerobic dopamine allows complete control of Parkinson's disease symptoms · 2025 · Related
  5. Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force · Bruno Dubois · 2007 · 1099 citations · Cited by this paper
  6. A review of FDG-PET biomarker analysis methods in Parkinson's disease · 2026 · Related
  7. MDS task force on mild cognitive impairment in Parkinson's disease: Critical review of PD‐MCI · Irene Litvan · 2011 · 812 citations · Cited by this paper
  8. Effects of deep brain stimulation on functional autonomy and quality of life in Parkinson's disease: A systematic review and meta-analysis · 2026 · Related
  9. A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research · Tanya Simuni · 2024 · 630 citations · Cited by this paper
  10. Association between age at Parkinson's disease onset and divorce: An exploratory analysis from the fox insight cohort · 2026 · Related
  11. Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's · Ganqiang Liu · 2016 · 280 citations · Cited by this paper
  12. Continuous apomorphine infusion modulates cortical hyperexcitability and abnormal plasticity in Parkinson's disease · 2026 · Related
  13. Parkinson's disease dementia: Definitions, guidelines, and research perspectives in diagnosis · Christopher G. Goetz · 2009 · 235 citations · Cited by this paper
  14. Rethinking the concept of disease modification in an evolving Parkinson's disease treatment landscape · 2026 · Related
  15. Global scales for cognitive screening in Parkinson's disease: Critique and recommendations · Matěj Škorvánek · 2017 · 228 citations · Cited by this paper
  16. Gut microbiome dysbiosis, short-chain fatty acid depletion and implications for neuroinflammation in atypical parkinsonian syndromes – a systematic review of patient cohorts · 2026 · Related
  17. Cognitive impairment in Parkinson’s disease: a report from a multidisciplinary symposium on unmet needs and future directions to maintain cognitive health · Jennifer G. Goldman · 2018 · 193 citations · Cited by this paper
  18. Aligning incentives for open science in biomedical research: Navigating funder and institutional perspectives · 2025 · Related
  19. Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life · Rachael Ashleigh Lawson · 2014 · 153 citations · Cited by this paper
  20. Prevalence and related factors of blood pressure regulation abnormalities in Parkinson's disease: Orthostatic hypotension and supine hypertension · 2025 · Related
  21. Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2024 Update · Kevin McFarthing · 2024 · 124 citations · Cited by this paper
  22. GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10‐Year Population‐Based Study · Aleksandra A. Szwedo · 2022 · 123 citations · Cited by this paper
  23. Cognitive Impairment in Parkinson’s Disease: Epidemiology, Clinical Profile, Protective and Risk Factors · Paulina González-Latapí · 2021 · 106 citations · Cited by this paper
  24. Measuring functional impact of cognitive impairment: Validation of the Parkinson's Disease Cognitive Functional Rating Scale · Jaime Kulisevsky · 2013 · 97 citations · Cited by this paper
  25. The Penn Parkinson's Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson's disease · Laura Brennan · 2016 · 75 citations · Cited by this paper
  26. Beta amyloid deposition and cognitive decline in Parkinson’s disease: a study of the PPMI cohort · Alexander S. Mihaescu · 2022 · 51 citations · Cited by this paper
  27. Accuracy of Patient and Care Partner Identification of Cognitive Impairments in Parkinson's Disease–Mild Cognitive Impairment · Jacquelynn N. Copeland · 2016 · 48 citations · Cited by this paper
  28. Cognitive Impairment in Parkinson’s Disease: An Updated Overview Focusing on Emerging Pharmaceutical Treatment Approaches · Yıldız Değirmenci · 2023 · 46 citations · Cited by this paper
  29. Development and initial testing of the Penn Parkinson's Daily Activities Questionnaire · Laura Brennan · 2015 · 32 citations · Cited by this paper
  30. Cognitive impairment in Parkinson's disease: Association between patient-reported and clinically measured outcomes · Kelly A. Mills · 2016 · 29 citations · Cited by this paper
  31. Therapeutic Development Paths for Cognitive Impairment in Parkinson's Disease: Report of a Regulatory Roundtable · Jamie Lynn Eberling · 2014 · 25 citations · Cited by this paper
  32. Neuropsychological Tests of Memory, Visuospatial, and Language Function in Parkinson's Disease: Review, Critique, and Recommendations · Ondřej Bezdíček · 2025 · 23 citations · Cited by this paper
  33. Patients’ experiences of Parkinson’s disease: a qualitative study in glucocerebrosidase and idiopathic Parkinson’s disease · Nicola Bonner · 2020 · 19 citations · Cited by this paper
  34. Attention/Working Memory and Executive Function in Parkinson's Disease: Review, Critique, and Recommendations · Roberta Biundo · 2025 · 18 citations · Cited by this paper
  35. Profiling people with Parkinson's disease at risk of cognitive decline: Insights from PPMI and ICICLE‐PD data · Dana Pourzinal · 2024 · 14 citations · Cited by this paper
  36. Cognitive profiles of patients with mild cognitive impairment due to Alzheimer's versus Parkinson's disease defined using a base rate approach: Implications for neuropsychological assessments · Anja Ophey · 2021 · 12 citations · Cited by this paper
  37. Cognition and Other Non-Motor Symptoms in an At-Risk Cohort for Parkinson’s Disease Defined by REM-Sleep Behavior Disorder and Hyposmia · Laure Pauly · 2024 · 12 citations · Cited by this paper
  38. Everyday Function in Alzheimer’s and Parkinson’s Patients with Mild Cognitive Impairment · Sara A. Becker · 2020 · 10 citations · Cited by this paper
  39. Assessing clinical meaningfulness in clinical trials for Alzheimer's disease: A U.S. regulatory perspective · Teresa Buracchio · 2025 · 10 citations · Cited by this paper

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