Research map: Brivaracetam in Combination with Midazolam and Ketamine Reduces Soman-Induced Seizure and Neurodegeneration in Rats

Back to the article

Papers in this map

  1. Mechanisms of Gamma Oscillations · György Buzsáki · 2012 · 3011 citations · Cited by this paper
  2. A Global Burden Perspective on Obstructive Sleep Apnea, Hearing Loss, and Early-Onset Cognitive Decline · 2026 · Related
  3. Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks · Marlene Bartos · 2006 · 2146 citations · Cited by this paper
  4. Motor Nerve Transfers in Complete and Incomplete Brachial Plexus Injuries: A State-of-the-Art Review · 2026 · Related
  5. Gamma Oscillation by Synaptic Inhibition in a Hippocampal Interneuronal Network Model · Xiao‐Jing Wang · 1996 · 1628 citations · Cited by this paper
  6. Upper-Limb Cryoneurolysis for Painful Post-Stroke Spasticity in Severely Impaired Upper Limbs: A Feasibility Case Series · 2026 · Related
  7. The Use of Antiavidin Antibody and Avidin-Biotin-Peroxidase Complex in Immunoperoxidase Technics · Su-Ming Hsu · 1981 · 1065 citations · Cited by this paper
  8. Utility and Wearability of the hitoe® Wearable ECG Monitoring System II for Detecting Covert Paroxysmal Atrial Fibrillation in Patients with Suspected ESUS Across Inpatient and Outpatient Settings: ACROSS-AF in ESUS · 2026 · Related
  9. A mechanism for generation of long-range synchronous fast oscillations in the cortex · Roger D. Traub · 1996 · 718 citations · Cited by this paper
  10. Impact of ABO Blood Group on Vascular Complications and on Clinical and Functional Outcome After Aneurysmal Subarachnoid Hemorrhage · 2026 · Related
  11. Circuit Mechanisms of Seizures in the Pilocarpine Model of Chronic Epilepsy: Cell Loss and Mossy Fiber Sprouting · Luiz E. Mello · 1993 · 697 citations · Cited by this paper
  12. Dynamic Changes in Endothelial Glycocalyx and Inflammatory Response in Patients with Acute Ischemic Stroke Treated with Mechanical Thrombectomy: Pathophysiological Aspects and Clinical Implications · 2026 · Related
  13. Neuropharmacological Mechanisms of Nerve Agent-induced Seizure and Neuropathology 1 1The animals used in studies performed in, or sponsored by, this Institute were handled in accordance with the principles stated in the Guide for the Care and Use of Laboratory Animals, proposed by the Committee on Care and Use of Laboratory Animals of the Institute of Laboratory Animal Resources, National Research Council, DHHA, National Institute of Health Publication #85–23, 1985, and the Animal Welfare Act of 1966, as amended. The opinions, or assertions contained herein are the private views of the authors, and are not to be construed as reflecting the views of the Department of the Army or the Department of Defense. · John H. McDonough · 1997 · 540 citations · Cited by this paper
  14. Machine Learning Approaches to Early Detection of Parkinson’s Disease Using Speech Analysis Technique · 2026 · Related
  15. Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions · Ross J. Tynan · 2010 · 537 citations · Cited by this paper
  16. Cadmium-Induced Toxicity as a Pathophysiological Mechanism for Parkinson’s Disease Onset in Individuals with Iron and Zinc Deficiencies and Chronic Obstructive Pulmonary Disease · 2026 · Related
  17. Control of nerve agent-induced seizures is critical for neuroprotection and survival☆ ☆The animals used in these studies were handled in accordance with the principles stated in the Guide for the Care and Use of Laboratory Animals, proposed by the Committee to Revise the Care and Use of Laboratory Animals of the Institute of Laboratory Animal Resources, National Research Council, and published by National Academy Press, 1996, and the Animal Welfare Act of 1966, as amended. The opinions or assertions contained herein are the private views of the authors, and are not to be construed as reflecting the views of the Department of the Army or the Department of Defense. · Tsung‐Ming Shih · 2003 · 288 citations · Cited by this paper
  18. Therapeutic Advances in Major NBIA Disorders: Current Strategies and Translational Challenges · 2026 · Related
  19. Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: Relationship to anti-convulsant properties · Michel R. Gillard · 2011 · 253 citations · Cited by this paper
  20. Pridopidine Mediated Sigma-1 Receptor Activation and Therapeutic Implications in Neurodegenerative Diseases · 2026 · Related
  21. A novel method for evaluating microglial activation using ionized calcium-binding adaptor protein-1 staining: cell body to cell size ratio · Iris B. Hovens · 2014 · 193 citations · Cited by this paper
  22. Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and Beyond · Wolfgang Löscher · 2016 · 187 citations · Cited by this paper
  23. Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A ( SV 2A) ligand with preclinical evidence of high brain permeability and fast onset of action · Jean‐Marie Nicolas · 2015 · 169 citations · Cited by this paper
  24. A combination of ketamine and diazepam synergistically controls refractory status epilepticus induced by cholinergic stimulation · Brandon S. Martin · 2007 · 142 citations · Cited by this paper
  25. Inflammatory changes during epileptogenesis and spontaneous seizures in a mouse model of mesiotemporal lobe epilepsy · Fabien Pernot · 2011 · 137 citations · Cited by this paper
  26. Comparative evaluation of benzodiazepines for control of soman-induced seizures · John H. McDonough · 1999 · 126 citations · Cited by this paper
  27. Prolonged inflammatory gene response following soman-induced seizures in mice · Franck Dhote · 2007 · 125 citations · Cited by this paper
  28. SV2 Acts via Presynaptic Calcium to Regulate Neurotransmitter Release · Qun-Fang Wan · 2010 · 124 citations · Cited by this paper
  29. Exposure to nerve agents: From status epilepticus to neuroinflammation, brain damage, neurogenesis and epilepsy · Marcio de Araujo Furtado · 2012 · 124 citations · Cited by this paper
  30. Treatment of Refractory and Super-refractory Status Epilepticus · Samhitha Rai · 2018 · 112 citations · Cited by this paper
  31. Spontaneous recurrent seizures after status epilepticus induced by soman in Sprague‐Dawley rats · Marcio de Araujo Furtado · 2010 · 108 citations · Cited by this paper
  32. Midazolam–ketamine dual therapy stops cholinergic status epilepticus and reduces Morris water maze deficits · Jérôme Niquet · 2016 · 77 citations · Cited by this paper
  33. Time-dependent reduction in the anticonvulsant effectiveness of diazepam against soman-induced seizures in guinea pigs · John H. McDonough · 2010 · 76 citations · Cited by this paper
  34. Safety, tolerability, and seizure control during long‐term treatment with adjunctive brivaracetam for partial‐onset seizures · Manuel Toledo · 2016 · 75 citations · Cited by this paper
  35. Combinations of ketamine and atropine are neuroprotective and reduce neuroinflammation after a toxic status epilepticus in mice · Franck Dhote · 2012 · 57 citations · Cited by this paper
  36. A review of the drug−drug interactions of the antiepileptic drug brivaracetam · Brian Darryl Moseley · 2020 · 57 citations · Cited by this paper
  37. Use of intravenous brivaracetam in status epilepticus: A multicenter registry · Estevo Santamarina · 2019 · 53 citations · Cited by this paper
  38. Rational polytherapy in the treatment of cholinergic seizures · Jérôme Niquet · 2019 · 52 citations · Cited by this paper
  39. First trial motor seizures triggered by amygdaloid stimulation in the rat · Ronald J. Racine · 1973 · 49 citations · Cited by this paper

Source: OpenAlex (CC0)