Research map: GnRH pulse frequency is decoded by distinct Gαs- and Gαq/11-mediated signaling pathways in gonadotropes in vitro

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  1. Molecular Biology of the Pituitary Gonadotropins · SOHEYLA D. GHARIB · 1990 · 706 citations · Cited by this paper
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  3. Frequency and Amplitude of Gonadotropin-Releasing Hormone Stimulation and Gonadotropin Secretion in the Rhesus Monkey* · L. Wildt · 1981 · 688 citations · Cited by this paper
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  7. A Pulsatile Gonadotropin-Releasing Hormone Stimulus is Required to Increase Transcription of the Gonadotropin Subunit Genes: Evidence for Differential Regulation of Transcription by Pulse Frequency In Vivo* · Daniel J. Haisenleder · 1991 · 363 citations · Cited by this paper
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  9. The Frequency of Gonadotropin-Releasing-Hormone Stimulation Differentially Regulates Gonadotropin Subunit Messenger Ribonucleic Acid Expression* · Alan C. Dalkin · 1989 · 326 citations · Cited by this paper
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  11. Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice · Elaine T. Alarid · 1996 · 301 citations · Cited by this paper
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  13. Egr-1 Is a Downstream Effector of GnRH and Synergizes by Direct Interaction with Ptx1 and SF-1 To Enhance Luteinizing Hormone β Gene Transcription · Jacques Tremblay · 1999 · 275 citations · Cited by this paper
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  15. Studies of Gonadotropin-Releasing Hormone (GnRH) Action Using nRH Receptor-Expressing Pituitary Cell Lines* · Ursula B. Kaiser · 1997 · 255 citations · Cited by this paper
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  17. Differential Effects of Gonadotropin-Releasing Hormone (GnRH) Pulse Frequency on Gonadotropin Subunit and GnRH Receptor Messenger Ribonucleic Acid Levels in Vitro* · Ursula B. Kaiser · 1997 · 230 citations · Cited by this paper
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  21. Involvement of Both Gq/11 and Gs Proteins in Gonadotropin-releasing Hormone Receptor-mediated Signaling in LβT2 Cells · Fujun Liu · 2002 · 184 citations · Cited by this paper
  22. Activation of Luteinizing Hormone β Gene by Gonadotropin-releasing Hormone Requires the Synergy of Early Growth Response-1 and Steroidogenic Factor-1 · Christoph Dorn · 1999 · 166 citations · Cited by this paper
  23. Differential Regulation of Gonadotropin Subunit Gene Promoter Activity by Pulsatile Gonadotropin-Releasing Hormone (GnRH) in Perifused LβT2 Cells: Role of GnRH Receptor Concentration · Grégoy Y. Bédécarrats · 2003 · 145 citations · Cited by this paper
  24. A Novel AP-1 Site Is Critical for Maximal Induction of the Follicle-stimulating Hormone β Gene by Gonadotropin-releasing Hormone · Djurdjica Coss · 2003 · 129 citations · Cited by this paper
  25. Gonadotropin-Releasing Hormone Pulse Frequency-Dependent Activation of Extracellular Signal-Regulated Kinase Pathways in Perifused LβT2 Cells · Haruhiko Kanasaki · 2005 · 109 citations · Cited by this paper
  26. Pulse Sensitivity of the Luteinizing Hormone β Promoter Is Determined by a Negative Feedback Loop Involving Early Growth Response-1 and Ngfi-A Binding Protein 1 and 2 · Mark A. Lawson · 2007 · 95 citations · Cited by this paper
  27. Activator Protein-1 and Smad Proteins Synergistically Regulate Human Follicle-Stimulating Hormone β-Promoter Activity · Ying Wang · 2008 · 90 citations · Cited by this paper
  28. GnRH—A Key Regulator of FSH · George Alexiades Stamatiades · 2018 · 75 citations · Cited by this paper
  29. p38 Mitogen-Activated Protein Kinase Is Critical for Synergistic Induction of the FSHβ Gene by Gonadotropin-Releasing Hormone and Activin through Augmentation of c-Fos Induction and Smad Phosphorylation · Djurdjica Coss · 2007 · 71 citations · Cited by this paper
  30. GnRH Pulse Frequency-Dependent Stimulation of FSHβ Transcription Is Mediated via Activation of PKA and CREB · Iain R. Thompson · 2013 · 70 citations · Cited by this paper
  31. Frequency-Dependent Regulation of Follicle-Stimulating Hormone β by Pulsatile Gonadotropin-Releasing Hormone Is Mediated by Functional Antagonism of bZIP Transcription Factors · Nick A. Ciccone · 2009 · 68 citations · Cited by this paper
  32. Regulation of Intracellular Signaling Cascades by GNRH Pulse Frequency in the Rat Pituitary: Roles for CaMK II, ERK, and JNK Activation1 · Laura L. Burger · 2008 · 64 citations · Cited by this paper
  33. A Composite Element that Binds Basic Helix Loop Helix and Basic Leucine Zipper Transcription Factors Is Important for Gonadotropin-Releasing Hormone Regulation of the Follicle-Stimulating Hormone β Gene · Nick A. Ciccone · 2008 · 53 citations · Cited by this paper
  34. Pulsatile Gonadotropin-Releasing Hormone Stimulation of Gonadotropin Subunit Transcription in Rat Pituitaries: Evidence for the Involvement of Jun N-Terminal Kinase But Not p38 · Daniel J. Haisenleder · 2007 · 49 citations · Cited by this paper
  35. Effects of peroxisome proliferator-activated receptor activation on gonadotropin transcription and cell mitosis induced by bone morphogenetic proteins in mouse gonadotrope LβT2 cells · Masaya Takeda · 2007 · 48 citations · Cited by this paper
  36. G Proteins and Autocrine Signaling Differentially Regulate Gonadotropin Subunit Expression in Pituitary Gonadotrope · Soon Gang Choi · 2012 · 43 citations · Cited by this paper
  37. Activin Modulates the Transcriptional Response of LβT2 Cells to Gonadotropin-Releasing Hormone and Alters Cellular Proliferation · Hao Zhang · 2006 · 42 citations · Cited by this paper
  38. Several GnRH Stimulation Frequencies Differentially Release FSH and LH from Isolated, Perfused Rat Anterior Pituitary Cells · Ruth T. Savoy‐Moore · 1987 · 41 citations · Cited by this paper
  39. Conservation of mechanisms mediating gonadotrophin-releasing hormone 1 stimulation of human luteinizing hormone β subunit transcription · Jérôme Fortin · 2008 · 39 citations · Cited by this paper

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