Research map: Not all NTRK fusions in mesenchymal neoplasia are driver events: implications on classification and targeted therapy

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  1. Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal · Jianjiong Gao · 2013 · 16180 citations · Cited by this paper
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  17. A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors · Alexander Edward Dela Cruz Drilon · 2017 · 446 citations · Cited by this paper
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  19. Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer · Alessio Amatu · 2019 · 314 citations · Cited by this paper
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  22. Recurrent NTRK1 Gene Fusions Define a Novel Subset of Locally Aggressive Lipofibromatosis-like Neural Tumors · Narasimhan P. Agaram · 2016 · 246 citations · Cited by this paper
  23. Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population · Christoph Benedikt Westphalen · 2021 · 209 citations · Cited by this paper
  24. Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network · George D. Demetri · 2020 · 148 citations · Cited by this paper
  25. Emerging soft tissue tumors with kinase fusions: An overview of the recent literature with an emphasis on diagnostic criteria · Cristina R. Antonescu · 2020 · 126 citations · Cited by this paper
  26. Molecular Analysis of Gene Fusions in Bone and Soft Tissue Tumors by Anchored Multiplex PCR–Based Targeted Next-Generation Sequencing · Suk Wai Lam · 2018 · 120 citations · Cited by this paper
  27. Soft tissue tumors characterized by a wide spectrum of kinase fusions share a lipofibromatosis‐like neural tumor pattern · Yu‐Chien Kao · 2020 · 95 citations · Cited by this paper
  28. TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors · Emiliano Cocco · 2020 · 73 citations · Cited by this paper
  29. Mesenchymal neoplasms with NTRK and other kinase gene alterations · Jessica L. Davis · 2021 · 68 citations · Cited by this paper
  30. The sensitivity of pan-TRK immunohistochemistry in solid tumours: A meta-analysis · Liesbeth M. Hondelink · 2022 · 45 citations · Cited by this paper
  31. NTRK‐rearranged spindle cell neoplasms are ubiquitous tumours of myofibroblastic lineage with a distinct methylation class · Arnault Tauziède‐Espariat · 2022 · 41 citations · Cited by this paper
  32. Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas · Shivaani Kummar · 2023 · 29 citations · Cited by this paper
  33. NTRK fusions in osteosarcoma are rare and non‐functional events · Baptiste Ameline · 2020 · 27 citations · Cited by this paper
  34. Chromosomal imbalances detected in NTRK‐rearranged sarcomas by the use of comparative genomic hybridisation · Ana Cristina Vargas · 2020 · 16 citations · Cited by this paper
  35. The spectrum and significance of secondary (co‐occurring) genetic alterations in sarcomas: the hallmarks of sarcomagenesis · Josephine Kam Tai K. Dermawan · 2023 · 15 citations · Cited by this paper
  36. NTRK fusion in soft tissue sarcomas harboring MDM2/CDK4 amplification: three case reports · Medhi Brahmi · 2021 · 10 citations · Cited by this paper
  37. Lipofibromatosis‐like neural tumors: Report of a case and review of 73 reported cases · Caden M. Ulschmid · 2023 · 5 citations · Cited by this paper
  38. Assessing targetable NTRK1/2/3 fusions in mesenchymal tumors via whole-exome RNA sequencing · Hélène Vanacker · 2025 · 5 citations · Cited by this paper
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