Research map: Novel and Experimental Therapies for Anal Fistula

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Papers in this map

  1. Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial · Julián Panés · 2016 · 1100 citations · Cited by this paper
  2. Medical Management of Inflammatory Pouch Disorders · 2025 · Related
  3. Alginate hydrogel dressings for advanced wound management · Miao Zhang · 2020 · 626 citations · Cited by this paper
  4. Redo Pelvic Pouch Procedure: Indications, Pitfalls, Technique, and Outcomes · 2025 · Related
  5. Video-assisted anal fistula treatment (VAAFT): a novel sphincter-saving procedure for treating complex anal fistulas · Piercarlo Meinero · 2011 · 332 citations · Cited by this paper
  6. Special Considerations in Anal Fistula Management · 2026 · Related
  7. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Anorectal Abscess, Fistula-in-Ano, and Rectovaginal Fistula · Wolfgang B. Gaertner · 2022 · 262 citations · Cited by this paper
  8. Salvaging Anastomoses After a Leak: A Practical Diagnostic and Treatment Algorithm · 2026 · Related
  9. Development of a Porcine Bladder Acellular Matrix with Well-Preserved Extracellular Bioactive Factors for Tissue Engineering · Bin Yang · 2010 · 207 citations · Cited by this paper
  10. Advances in Colorectal Anastomoses · 2026 · Related
  11. Identification and characterization of bioactive factors in bladder submucosa matrix · So Young Chun · 2007 · 181 citations · Cited by this paper
  12. Ileal Pouch Physiology: Clinical Implications · 2026 · Related
  13. Multifunctional Hydrogels Prepared by Dual Ion Cross-Linking for Chronic Wound Healing · Yonghui Li · 2017 · 164 citations · Cited by this paper
  14. Ileal Anal Pouch Dysfunction and Quality of Life · 2025 · Related
  15. A Systematic review and meta-analysis of the efficacy and safety of video-assisted anal fistula treatment (VAAFT) · Sameh Hany Emile · 2017 · 154 citations · Cited by this paper
  16. The NICE Procedure: Surgical Technique and Technical Considerations · 2026 · Related
  17. Closure of fistula‐in‐ano with laser – FiLaC™: an effective novel sphincter‐saving procedure for complex disease · Paolo Giamundo · 2013 · 147 citations · Cited by this paper
  18. Pivotal Clinical Trials on the Management of Diverticular Disease · 2026 · Related
  19. ACG Clinical Guideline: Management of Crohn's Disease in Adults · Gary R. Lichtenstein · 2025 · 146 citations · Cited by this paper
  20. Anal Fistula—Principles of Initial Management: Sepsis Control, Drainage, and Timing of Definitive Surgery · 2026 · Related
  21. Expanded adipose-derived stem cells for the treatment of complex perianal fistula including Crohn's disease · Damián García‐Olmo · 2008 · 143 citations · Cited by this paper
  22. Transanal opening of intersphincteric space (TROPIS) - A new procedure to treat high complex anal fistula · Pankaj Kumar Garg · 2017 · 116 citations · Cited by this paper
  23. Proteomic composition and immunomodulatory properties of urinary bladder matrix scaffolds in homeostasis and injury · Kaitlyn Sadtler · 2017 · 105 citations · Cited by this paper
  24. Solubilized extracellular matrix from brain and urinary bladder elicits distinct functional and phenotypic responses in macrophages · Fan Wei Meng · 2015 · 89 citations · Cited by this paper
  25. A systematic review and meta-analysis of the safety and efficacy of fistula laser closure · Hossam Ayman Elfeki · 2020 · 86 citations · Cited by this paper
  26. Autologous adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistula: A randomized clinical trial with long-term follow-up · Mariano García‐Arranz · 2019 · 85 citations · Cited by this paper
  27. Sphincter-Sparing Anal Fistula Repair: Are We Getting Better? · Jeremy J. Sugrue · 2017 · 70 citations · Cited by this paper
  28. Video-Assisted Anal Fistula Treatment (VAAFT) in Cryptoglandular fistula-in-ano: A systematic review and proportional meta-analysis · Pankaj Kumar Garg · 2017 · 69 citations · Cited by this paper
  29. Refractory Complex Crohn’s Perianal Fistulas: A Role for Autologous Microfragmented Adipose Tissue Injection · Silvio Laureti · 2019 · 68 citations · Cited by this paper
  30. Video-Assisted Anal Fistula Treatment · Piercarlo Meinero · 2014 · 65 citations · Cited by this paper
  31. Prospective pilot study of anorectal fistula closure with the OTSC Proctology · R. L. Prosst · 2014 · 59 citations · Cited by this paper
  32. Transanal opening of the intersphincteric space: a novel sphincter‐sparing procedure to treat 325 high complex anal fistulas with long‐term follow‐up · Pankaj Kumar Garg · 2021 · 55 citations · Cited by this paper
  33. Biomedical potential of alginate wound dressings – From preclinical studies to clinical applications: A review · Łukasz Mazurek · 2025 · 49 citations · Cited by this paper
  34. Efficacy and Safety of Treatment of Complex Idiopathic Fistula-in-Ano Using Autologous Centrifuged Adipose Tissue Containing Progenitor Cells: A Randomized Controlled Trial · Simona Ascanelli · 2021 · 48 citations · Cited by this paper
  35. Transanal Opening of Intersphincteric Space for Fistula-in-Ano · Yubo Li · 2021 · 46 citations · Cited by this paper
  36. Evaluation of Viability and Proliferative Activity of Human Urothelial Cells Cultured Onto Xenogenic Tissue-Engineered Extracellular Matrices · Niall F. Davis · 2011 · 44 citations · Cited by this paper
  37. Could FiLaC™ be effective in the treatment of anal fistulas? A systematic review of observational studies and proportional meta‐analysis · Maximos Frountzas · 2020 · 42 citations · Cited by this paper
  38. Crohn’s Disease-Associated and Cryptoglandular Fistulas: Differences and Similarities · Zhou Zhou · 2023 · 41 citations · Cited by this paper
  39. PERFACT procedure: A new concept to treat highly complex anal fistula · Pankaj Kumar Garg · 2015 · 35 citations · Cited by this paper

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