Research map: Inhibiting HIF ‐1α‐Induced miR ‐663b Improves Pulmonary Arterial Hypertension by Reducing Dysfunctions of PASMCs Through Repressing Sirt1‐ ZBP1 ‐Mediated PANoptosis

Back to the article

Papers in this map

  1. MicroRNAs: small RNAs with a big role in gene regulation · Lin He · 2004 · 7125 citations · Cited by this paper
  2. Pretreatment With BTK Inhibitors Improved the Sensitivity of DLBCL Cells to CAR ‐T Cells in a Coculture System by Downregulating the Polarisation of M2 Macrophages · 2026 · Related
  3. AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance · Daniel Garcia · 2017 · 2058 citations · Cited by this paper
  4. GGAs : Regulation of Multiple Sorting Pathways and Potential Association With Human Diseases · 2026 · Related
  5. AMPK activators: mechanisms of action and physiological activities · Joungmok Kim · 2016 · 833 citations · Cited by this paper
  6. Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways · 2026 · Related
  7. Diagnosis and Treatment of Pulmonary Arterial Hypertension · Nicole F. Ruopp · 2022 · 699 citations · Cited by this paper
  8. Superoxide Dismutase–Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications · 2026 · Related
  9. SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection · Nunzia D’Onofrio · 2017 · 393 citations · Cited by this paper
  10. PGK1 Drives Glial Glycolytic Reprogramming to Mediate Isoflurane‐Induced Cognitive Impairment in Aged Mice · 2026 · Related
  11. β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK) · Jonathan S. Oakhill · 2010 · 320 citations · Cited by this paper
  12. FTO ‐Catalysed Demethylation of LUR1 mRNA Suppresses Macrophage Lipid Accumulation and Aortic Atherosclerosis · 2026 · Related
  13. Perivascular Inflammation in Pulmonary Arterial Hypertension · Yijie Hu · 2020 · 246 citations · Cited by this paper
  14. HDAC2 ‐Mediated SMAD7 Stabilisation Activates Wnt/β‐Catenin Signalling to Drive DNA Damage Repair and Cisplatin Resistance in Ovarian Cancer · 2026 · Related
  15. Tenascin-C Is Induced With Progressive Pulmonary Vascular Disease in Rats and Is Functionally Related to Increased Smooth Muscle Cell Proliferation · Peter Lloyd Jones · 1996 · 195 citations · Cited by this paper
  16. The STAT3‐CCND2 Axis Drives a Proliferative Metaplastic Precursor Population in Gastric Intestinal Metaplasia · 2026 · Related
  17. Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway · Abubakar Wani · 2021 · 185 citations · Cited by this paper
  18. Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury · 2026 · Related
  19. Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis · Sufang Zhong · 2023 · 170 citations · Cited by this paper
  20. circFOXP1 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Regulating EREG / MAPK / ERK Axis · 2026 · Related
  21. AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy · Xinyi Lü · 2021 · 145 citations · Cited by this paper
  22. Resveratrol: Mechanistic and therapeutic perspectives in pulmonary arterial hypertension · Elaheh Mirhadi · 2020 · 95 citations · Cited by this paper
  23. MicroRNA-150 relieves vascular remodeling and fibrosis in hypoxia-induced pulmonary hypertension · Ying Li · 2018 · 90 citations · Cited by this paper
  24. Mechanistic Phase II Clinical Trial of Metformin in Pulmonary Arterial Hypertension · Evan L. Brittain · 2020 · 87 citations · Cited by this paper
  25. Dimethyl fumarate inhibits necroptosis and alleviates systemic inflammatory response syndrome by blocking the RIPK1-RIPK3-MLKL axis · Fuli Shi · 2023 · 78 citations · Cited by this paper
  26. Mitophagy restricts BAX/BAK-independent, Parkin-mediated apoptosis · Giovanni Quarato · 2023 · 64 citations · Cited by this paper
  27. Sulforaphane alleviated vascular remodeling in hypoxic pulmonary hypertension via inhibiting inflammation and oxidative stress · Jinjin Pan · 2022 · 57 citations · Cited by this paper
  28. Metformin relieves acute respiratory distress syndrome by reducing miR-138 expression. · Yu Ll · 2018 · 43 citations · Cited by this paper
  29. Calpain‐1 mediates vascular remodelling and fibrosis via HIF‐1α in hypoxia‐induced pulmonary hypertension · Haiyan Deng · 2022 · 43 citations · Cited by this paper
  30. Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism · Bin Li · 2024 · 41 citations · Cited by this paper
  31. AMPK negatively regulates RANKL-induced osteoclast differentiation by controlling oxidative stress · Miori Tanaka · 2023 · 38 citations · Cited by this paper
  32. EGCG targeting STAT3 transcriptionally represses PLXNC1 to inhibit M2 polarization mediated by gastric cancer cell-derived exosomal miR-92b-5p · Jianfeng Yi · 2024 · 36 citations · Cited by this paper
  33. The Zinc-dependent HDACs: Non-histone Substrates and Catalytic Deacylation Beyond Deacetylation · Weiping Zheng · 2022 · 34 citations · Cited by this paper
  34. Activation of AMPK Prevents Monocrotaline-Induced Extracellular Matrix Remodeling of Pulmonary Artery · Shaojun Li · 2016 · 28 citations · Cited by this paper
  35. Sirt1 activation negatively regulates overt apoptosis in Mtb-infected macrophage through Bax · Hong Seuk Yang · 2020 · 25 citations · Cited by this paper
  36. Urolithin A Protects against Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Smooth Muscle Cell Pyroptosis via AMPK/NF-κB/NLRP3 Signaling · Xinjie He · 2024 · 23 citations · Cited by this paper
  37. Exosomal miR-663b from “M1” macrophages promotes pulmonary artery vascular smooth muscle cell dysfunction through inhibiting the AMPK/Sirt1 axis · Honghong Ma · 2023 · 20 citations · Cited by this paper
  38. Omentin-1 ameliorates pulmonary arterial hypertension by inhibiting endoplasmic reticulum stress through AMPKα signaling · Xinyu Deng · 2024 · 16 citations · Cited by this paper
  39. Melatonin effects on oxidative stress and on TLR4/NF-kβ inflammatory pathway in the right ventricle of rats with pulmonary arterial hypertension · Cristiane Dias Lisboa · 2024 · 15 citations · Cited by this paper

Source: OpenAlex (CC0)