Research map: Stress and HPA axis dysfunction impact diverse epilepsy outcomes including psychiatric comorbidities and SUDEP

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Papers in this map

  1. An Overview of Heart Rate Variability Metrics and Norms · Fred Shaffer · 2017 · 7265 citations · Cited by this paper
  2. Parental miscarried helping, self-efficacy, and treatment adherence among adolescents and young adults with epilepsy: A mediation model · 2026 · Related
  3. ILAE Official Report: A practical clinical definition of epilepsy · Robert S. Fisher · 2014 · 6123 citations · Cited by this paper
  4. Variant-specific response of KCNT1 gain-of-function mutations to quinidine · 2026 · Related
  5. Early Identification of Refractory Epilepsy · Patrick Kwan · 2000 · 5230 citations · Cited by this paper
  6. Phenotype and genotype of people with epilepsy and GABAA receptor gene variants: Genetic and clinical characterization of six children in China · 2026 · Related
  7. Suicide as an outcome for mental disorders · Elizabeth Clare Harris · 1997 · 2602 citations · Cited by this paper
  8. Prevalence of epilepsy in Portugal: An epidemiologic population-based study (EPIPORT) · 2026 · Related
  9. Glucocorticoids and Hippocampal Atrophy in Neuropsychiatric Disorders · Robert Morris Sapolsky · 2000 · 2018 citations · Cited by this paper
  10. Psychiatric symptoms and quality of life in Saudi individuals with epilepsy receiving perampanel: A cross-sectional comparative study · 2026 · Related
  11. The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress · Sean M. Smith · 2006 · 1960 citations · Cited by this paper
  12. MRI-based machine learning model to distinguish hippocampal sclerosis (HS) ILAE type 1 and no HS gliosis only in medial temporal lobe epilepsy · 2026 · Related
  13. ENDOCRINOLOGY OF THE STRESS RESPONSE · Evangelia Charmandari · 2005 · 1806 citations · Cited by this paper
  14. Is temporal lobe epilepsy a progressive disease? Insights from a 5-HT1A receptor partial volume correction study · 2026 · Related
  15. Chronic Stress Induces Contrasting Patterns of Dendritic Remodeling in Hippocampal and Amygdaloid Neurons · Ajai Vyas · 2002 · 1664 citations · Cited by this paper
  16. Long-term risk of major adverse cardiovascular events in patients with epilepsy: Roles of childhood onset and antiseizure medications · 2026 · Related
  17. The Cloning of a Family of Genes That Encode the Melanocortin Receptors · Kathleen Grace Mountjoy · 1992 · 1654 citations · Cited by this paper
  18. The role of DHH motifs in PRUNE1 gene on ion channels: A new insight into epilepsy pathogenesis · 2026 · Related
  19. Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs · Zhibin ZC Chen · 2017 · 1565 citations · Cited by this paper
  20. Repetitive transcranial magnetic stimulation for epilepsy: Efficacy and safety · 2026 · Related
  21. Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients · Charles B. Nemeroff · 1984 · 1488 citations · Cited by this paper
  22. Limbic system mechanisms of stress regulation: Hypothalamo-pituitary-adrenocortical axis · James P. Herman · 2005 · 1333 citations · Cited by this paper
  23. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons · Yoshifumi Watanabe · 1992 · 1214 citations · Cited by this paper
  24. Incidence and mechanisms of cardiorespiratory arrests in epilepsy monitoring units (MORTEMUS): a retrospective study · Philippe Ryvlin · 2013 · 1145 citations · Cited by this paper
  25. Psychiatric Comorbidity in Epilepsy: A Population‐Based Analysis · José Francisco Téllez‐Zenteno · 2007 · 1123 citations · Cited by this paper
  26. Depression and Cardiac Mortality · Brenda W.J.H. Penninx · 2001 · 929 citations · Cited by this paper
  27. Unraveling the mysteries of anxiety and its disorders from the perspective of emotion theory. · David Harrison Barlow · 2000 · 898 citations · Cited by this paper
  28. The Bezold-Jarisch reflex revisited: Clinical implications of inhibitory reflexes originating in the heart · Allyn L. Mark · 1983 · 732 citations · Cited by this paper
  29. Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention · Orrin Devinsky · 2016 · 730 citations · Cited by this paper
  30. Beyond Heart Rate Variability · Julian Francis Thayer · 2006 · 707 citations · Cited by this paper
  31. Variations in the Hypothalamic-Pituitary-Adrenal Response to Stress during the Estrous Cycle in the Rat · Victor Viau · 1991 · 671 citations · Cited by this paper
  32. Cortisol regulation in posttraumatic stress disorder and major depression: A chronobiological analysis · Rachel Yehuda · 1996 · 655 citations · Cited by this paper
  33. Unifying the definitions of sudden unexpected death in epilepsy · Lina A. M. Nashef · 2011 · 631 citations · Cited by this paper
  34. Epilepsy, suicidality, and psychiatric disorders: A bidirectional association · Dale C. Hesdorffer · 2012 · 610 citations · Cited by this paper
  35. Expression and neuropeptidergic characterization of estrogen receptors (ER? and ER?) throughout the rat brain: Anatomical evidence of distinct roles of each subtype · Nathalie Laflamme · 1998 · 585 citations · Cited by this paper
  36. Epilepsy and risk of suicide: a population-based case–control study · Jakob Christensen · 2007 · 561 citations · Cited by this paper
  37. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones · Ashley Heck · 2018 · 542 citations · Cited by this paper
  38. Depression and suicide attempt as risk factors for incident unprovoked seizures · Dale C. Hesdorffer · 2005 · 530 citations · Cited by this paper
  39. Predictors of pharmacoresistant epilepsy · Nikolas Hitiris · 2007 · 530 citations · Cited by this paper

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