Research map: FAM151A Regulates Insulin Secretion in Pancreatic β-Cells and Is Implicated in Pathogenesis of Type 2 Diabetes Mellitus

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  1. Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes · Gordon C. Weir · 2004 · 1131 citations · Cited by this paper
  2. Fibroblast- and Macrophage-Derived Thrombospondin-1 Orchestrates the Fibroinflammatory Niche in Metabolic Dysfunction-Associated Steatohepatitis-Induced Fibrosis · 2026 · Related
  3. RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes · Yurong Xin · 2016 · 777 citations · Cited by this paper
  4. Lifestyle Combination Patterns as Key Modifiable Factors for Type 2 Diabetes Mellitus Risk among Middle-Aged Korean Men · 2026 · Related
  5. Mechanisms controlling pancreatic islet cell function in insulin secretion · Jonathan E. Campbell · 2021 · 654 citations · Cited by this paper
  6. Optimizing Early Detection of Diabetic Kidney Disease through Synergistic Biomarkers and Serum Metabolites in Humans · 2026 · Related
  7. Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes · Maria Lytrivi · 2019 · 416 citations · Cited by this paper
  8. Neutrophil-Linked Inflammatory Mechanisms and Biomarkers in Diabetic Microvascular Complications · 2026 · Related
  9. Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets · Michael R. DiGruccio · 2016 · 368 citations · Cited by this paper
  10. Sleeve Gastrectomy with Fundoplication Enhances Metabolic Health in Obese Rats via Ghrelin Pathway Modulation and Multi-Organ Regulation · 2026 · Related
  11. Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance · Bjarne Hove‐Jensen · 2016 · 281 citations · Cited by this paper
  12. Clinical and Preclinical Obesity in Korean Adults from 2014 to 2023 (Diabetes Metab J 2026;50:127-38) · 2026 · Related
  13. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity · Wei Ying · 2018 · 277 citations · Cited by this paper
  14. Redefining β-Cell Function in Type 2 Diabetes Mellitus: From Comprehensive Assessment to Precision Medicine · 2026 · Related
  15. Cytokine production by islets in health and diabetes: cellular origin, regulation and function · Marc Yves Donath · 2010 · 228 citations · Cited by this paper
  16. Impact of Lifestyle on the Association between Ambient Air Pollution and Insulin Resistance · 2026 · Related
  17. Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer · Kanchan Sonkar · 2019 · 221 citations · Cited by this paper
  18. Adiponectin as a Predictor of Metabolic Dysfunction-Associated Steatotic Liver Disease and Non-Alcoholic Fatty Liver Disease: A 17-Year Korean Cohort Study (Diabetes Metab J 2026;50:331-42) · 2026 · Related
  19. Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice · Ja Young Kim-Muller · 2016 · 201 citations · Cited by this paper
  20. Clinical and Preclinical Obesity in Korean Adults from 2014 to 2023 (Diabetes Metab J 2026;50:127-38) · 2026 · Related
  21. SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes · Janna A. van Diepen · 2017 · 198 citations · Cited by this paper
  22. Deciphering Pancreatic Islet β Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level · Wei‐Lin Qiu · 2017 · 180 citations · Cited by this paper
  23. Skin-Derived Cues Control Arborization of Sensory Dendrites in Caenorhabditis elegans · Yehuda Salzberg · 2013 · 175 citations · Cited by this paper
  24. Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway · Sophie L. Lewandowski · 2020 · 156 citations · Cited by this paper
  25. Single-Cell RNA-Seq of the Pancreatic Islets––a Promise Not yet Fulfilled? · Yue Julia Wang · 2018 · 134 citations · Cited by this paper
  26. Metabolic cycles and signals for insulin secretion · Matthew J. Merrins · 2022 · 131 citations · Cited by this paper
  27. Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism · Jessica R. Gooding · 2015 · 106 citations · Cited by this paper
  28. Islet-1 Is Essential for Pancreatic β-Cell Function · Benjamin N. Ediger · 2014 · 98 citations · Cited by this paper
  29. A review on insulin trafficking and exocytosis · Mehrdad Vakilian · 2019 · 74 citations · Cited by this paper
  30. NADH Shuttle System Regulates KATPChannel-dependent Pathway and Steps Distal to Cytosolic Ca2+ Concentration Elevation in Glucose-induced Insulin Secretion · Kazuhiro Eto · 1999 · 64 citations · Cited by this paper
  31. MafA, NeuroD1, and HNF1β synergistically activate the Slc2a2 (Glut2) gene in β-cells · Yuka Ono · 2021 · 36 citations · Cited by this paper
  32. MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells · Ling‐Ling Chen · 2025 · 28 citations · Cited by this paper
  33. Inosine-stimulated insulin release and metabolism of inosine in isolated mouse pancreatic islets · Kirsten Capito · 1976 · 27 citations · Cited by this paper
  34. Proteomic analysis of AQP11-null kidney: Proximal tubular type polycystic kidney disease · Tatsuya Saito · 2017 · 22 citations · Cited by this paper
  35. IDF Global Clinical Practice Recommendations for Managing Type 2 Diabetes 2025 · 2025 · 20 citations · Cited by this paper
  36. Intermittent protein restriction protects islet β cells and improves glucose homeostasis in diabetic mice · Siying Wei · 2021 · 16 citations · Cited by this paper
  37. Transcriptional control of pancreatic β-cell identity and plasticity during the pathogenesis of type 2 diabetes · Ziyin Zhang · 2022 · 15 citations · Cited by this paper
  38. Excessive production of nitric oxide by macrophages from DP-BB rats is secondary to the T-lymphopenic state of these animals · A. Lau · 1998 · 13 citations · Cited by this paper
  39. A species difference in nucleoside phosphorylase activity and inosine-stimulated insulin secretion in isolated islets of Langerhans · Iain Leslie Campbell · 1977 · 12 citations · Cited by this paper

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