Research map: Amyloid-associated cognitive trajectories in aging dogs mirror early changes in humans

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  1. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade · Clifford R. Jack · 2009 · 4894 citations · Cited by this paper
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  24. The canine as an animal model of human aging and dementia · Brian J Cummings · 1996 · 284 citations · Cited by this paper
  25. β-Amyloid Accumulation Correlates with Cognitive Dysfunction in the Aged Canine · Brian J Cummings · 1996 · 244 citations · Cited by this paper
  26. Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated amyloid β · Elizabeth C. Mormino · 2017 · 208 citations · Cited by this paper
  27. Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction · Carl W. Cotman · 2002 · 185 citations · Cited by this paper
  28. Visual-discrimination learning ability and β-amyloid accumulation in the dog · Elizabeth Head · 1998 · 175 citations · Cited by this paper
  29. Toward more predictive genetic mouse models of Alzheimer's disease · Kristen D. Onos · 2015 · 166 citations · Cited by this paper
  30. Episodic memory on the path to Alzheimer's disease · Michela Gallagher · 2011 · 160 citations · Cited by this paper
  31. Predicting amyloid PET and tau PET stages with plasma biomarkers · Clifford R. Jack · 2023 · 159 citations · Cited by this paper
  32. A canine model of human aging and Alzheimer's disease · Elizabeth Head · 2013 · 157 citations · Cited by this paper
  33. Canine Cognitive Dysfunction and Alzheimer’s Disease – Two Facets of the Same Disease? · Sonja Prpar Mihevc · 2019 · 143 citations · Cited by this paper
  34. Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging · Min‐Ying Su · 1998 · 139 citations · Cited by this paper
  35. Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function · Christina T. Siwak-Tapp · 2007 · 137 citations · Cited by this paper
  36. Spatial learning and memory as a function of age in the dog. · Elizabeth Head · 1995 · 134 citations · Cited by this paper
  37. Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation · Michelle E. Farrell · 2020 · 132 citations · Cited by this paper
  38. Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice · Pradoldej M Sompol · 2017 · 123 citations · Cited by this paper
  39. Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies · Reisa Anne Sperling · 2024 · 113 citations · Cited by this paper

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