Research map: Frailty, clinical outcomes, and treatment effects of a care bundle in acute intracerebral haemorrhage: a post-hoc analysis of the INTERACT3 trial

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  1. Frailty in elderly people · Andrew Paul Clegg · 2013 · 9698 citations · Cited by this paper
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  11. The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial · Lu Ma · 2023 · 402 citations · Cited by this paper
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  13. Association of the clinical frailty scale with hospital outcomes · S J Wallis · 2015 · 361 citations · Cited by this paper
  14. Incidence of dementia after age 90 years and association with APOE genotype, race, and sex in the USA: the LifeAfter90 prospective cohort study · 2026 · Related
  15. Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage · Stuart J. Connolly · 2024 · 278 citations · Cited by this paper
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  17. How to construct a frailty index from an existing dataset in 10 steps · Olga Theou · 2023 · 194 citations · Cited by this paper
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  19. Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis · Jennifer Kirsty Burton · 2022 · 171 citations · Cited by this paper
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  21. Frailty and cerebrovascular disease: Concepts and clinical implications for stroke medicine · Nicholas R. Evans · 2021 · 134 citations · Cited by this paper
  22. Clinical frailty independently predicts early mortality after ischaemic stroke · Nicholas R. Evans · 2020 · 128 citations · Cited by this paper
  23. European Stroke Organisation (ESO) and European Association of Neurosurgical Societies (EANS) guideline on stroke due to spontaneous intracerebral haemorrhage · Thorsten Steiner · 2025 · 99 citations · Cited by this paper
  24. Accumulation of Deficits as a Key Risk Factor for Cardiovascular Morbidity and Mortality: A Pooled Analysis of 154 000 Individuals · Mohammed A. Farooqi · 2020 · 91 citations · Cited by this paper
  25. Frailty and stroke thrombectomy outcomes—an observational cohort study · Nevan Joyce · 2022 · 59 citations · Cited by this paper
  26. Treatment for intracerebral hemorrhage: Dawn of a new era · David Julian Seiffge · 2024 · 50 citations · Cited by this paper
  27. Prevalence, measurement, and implications of frailty in stroke survivors: An analysis of three global aging cohorts · Peter Hanlon · 2023 · 35 citations · Cited by this paper
  28. Frailty and stroke: Global implications for assessment, research, and clinical care—A WSO scientific statement · Nicholas R. Evans · 2025 · 35 citations · Cited by this paper
  29. Premorbid frailty predicts short- and long-term outcomes of reperfusion treatment in acute stroke · Andrea Pilotto · 2022 · 26 citations · Cited by this paper
  30. Frailty and spontaneous intracerebral hemorrhage: Does the modified frailty index predict mortality? · Michael G. Kim · 2020 · 24 citations · Cited by this paper
  31. INTEnsive care bundle with blood pressure reduction in acute cerebral hemorrhage trial (INTERACT3): study protocol for a pragmatic stepped-wedge cluster-randomized controlled trial · Lili Song · 2021 · 24 citations · Cited by this paper
  32. Intracerebral Hemorrhage: Advances, Knowledge Gaps, and Future Directions · Tao Liu · 2025 · 18 citations · Cited by this paper
  33. Frailty and Early Mortality following Intracerebral Hemorrhage · Benjamin P. Lewis · 2024 · 12 citations · Cited by this paper
  34. The effect of frailty on mortality and functional outcomes in spontaneous intracerebral haemorrhage · S.H. Ong · 2024 · 10 citations · Cited by this paper
  35. Premorbid Blood Pressure Control Modifies Risk of DWI Lesions With Acute Blood Pressure Reduction in Intracerebral Hemorrhage · Mohamed Ridha · 2024 · 8 citations · Cited by this paper
  36. Predisposing Factors, Pathologies, and Precipitating Factors Causing Intracerebral Hemorrhage · Alice Hosking · 2025 · 8 citations · Cited by this paper
  37. Frailty and the short-term prognosis of patients with intracranial hemorrhage: A meta-analysis · Caiyun Li · 2025 · 1 citation · Cited by this paper
  38. Impact of Ultra-Early Perioperative Antihypertensive Therapy in Acute Intracerebral Hemorrhage · Tao Liu · 2026 · 1 citation · Cited by this paper

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