Research map: Rejoinder: “Adaptive versus fixed designs in confirmatory clinical trials: Centering the choice on ethics”
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Papers in this map
Equipoise and the Ethics of Clinical Research
· Benjamin Freedman · 1987 · 2354 citations · Cited by this paper
Commentary on adaptive versus fixed designs in confirmatory clinical trials: centering the choice on ethics, by Bass et al.
· Janet Turk Wittes · 2026 · 1 citation · Cites this paper
Covariate adjustment in randomized trials: An overview
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Streptomycin Treatment of Pulmonary Tuberculosis: A Medical Research Council Investigation
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Covariate adjustment in randomized clinical trials: From general theory to practical insights
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The scandal of poor medical research
· Douglas G. Altman · 1994 · 911 citations · Cited by this paper
Additional crossovers in cluster randomised crossover trials do not always increase statistical power
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Adaptive designs undertaken in clinical research: a review of registered clinical trials
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Point estimation for adaptive trial designs I: A methodological review
· David S. Robertson · 2022 · 57 citations · Cited by this paper
A review of use of external data and update on reporting standards in Sequential Multiple-Assignment Randomised Trials
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The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias
· Puvan Tharmanathan · 2008 · 43 citations · Cited by this paper
Shaping the future of clinical trials through strategic foresight
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Learning health systems, clinical equipoise and the ethics of response adaptive randomisation
· Alex John London · 2017 · 41 citations · Cited by this paper
Bayesian design and analysis of two-arm cluster randomised trials using assurance: Extension to binary outcomes and comparison of Markov chain Monte Carlo and Integrated Nested Laplace Approximations
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On the use of non-concurrent controls in platform trials: a scoping review
· Marta Bofill Roig · 2023 · 26 citations · Cited by this paper
Surrogate markers used as efficacy endpoints in NIH-sponsored clinical trials
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Varieties of Community Uncertainty and Clinical Equipoise
· Alex John London · 2023 · 10 citations · Cited by this paper
Evidence supporting European Medicines Agency drug approvals (2020–2023): A cross-sectional study of trial design and outcomes
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Confirmatory evidence supporting single pivotal trial new drug approvals by the Food and Drug Administration, 2015 through 2023
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