Research map: Protective Effect of Isoflurane on Hypoxia/Reoxygenation‐Induced Myocardial Injury via miR‐548a‐5p Regulation of PTEN

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  1. The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate · Tomohiko Maehama · 1998 · 3127 citations · Cited by this paper
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  11. The role of PI3K/AKT signaling pathway in myocardial ischemia-reperfusion injury · Rui-ming Deng · 2023 · 194 citations · Cited by this paper
  12. Nano‐Rosmarinic Acid Protects Against Chlorfenapyr‐Induced Testicular Toxicity Through Modulation of NRF2/HO‐1 and NF‐κB/NLRP3 Signaling Pathways · 2026 · Related
  13. Anaesthetic drugs and survival: a Bayesian network meta-analysis of randomized trials in cardiac surgery · Giovanni Landoni · 2013 · 187 citations · Cited by this paper
  14. Zingerone Alleviates Acetaminophen‐Induced Liver Damage by Regulating Oxidative Stress, Inflammation, Apoptosis, Endoplasmic Reticulum Stress, and Autophagy · 2026 · Related
  15. miRNA dysregulation is an emerging modulator of genomic instability · Ana P. Ferragut Cardoso · 2021 · 164 citations · Cited by this paper
  16. SGLT2 Inhibition Attenuates Hippocampal Injury and Cognitive Impairment in Adult‐Onset Hypothyroidism · 2026 · Related
  17. Clinical Validation of a Novel High-Sensitivity Cardiac Troponin I Assay for Early Diagnosis of Acute Myocardial Infarction · Jasper Boeddinghaus · 2018 · 159 citations · Cited by this paper
  18. Silymarin Modulates 3‐Nitropropionic Acid‐Induced Oxidative Neurotoxicity and Apoptosis Through the Inhibition of TRPV1 Channel in Mouse Brain and Hippocampal Neurons · 2026 · Related
  19. Ginsenoside Rb1 Inhibits Cardiomyocyte Autophagy via PI3K/Akt/mTOR Signaling Pathway and Reduces Myocardial Ischemia/Reperfusion Injury · Guo-Wei Qin · 2021 · 159 citations · Cited by this paper
  20. Industrial Hydrocarbons Exposure Deteriorates Sperm Integrity and Reproductive Function · 2026 · Related
  21. Targeting WWP1 ameliorates cardiac ischemic injury by suppressing KLF15-ubiquitination mediated myocardial inflammation · Xia Lu · 2022 · 80 citations · Cited by this paper
  22. PTEN inhibitor improves vascular remodeling and cardiac function after myocardial infarction through PI3k/Akt/VEGF signaling pathway · Qiuting Feng · 2020 · 62 citations · Cited by this paper
  23. ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway · Lingling Chang · 2019 · 54 citations · Cited by this paper
  24. Mangiferin Potentiates Neuroprotection by Isoflurane in Neonatal Hypoxic Brain Injury by Reducing Oxidative Stress and Activation of Phosphatidylinositol-3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling · Jiashui Xi · 2018 · 41 citations · Cited by this paper
  25. Cardiac troponin, CK-MB and myoglobin for the early detection of acute myocardial infarction and monitoring of reperfusion following thrombolytic therapy · Fred S. Apple · 1995 · 40 citations · Cited by this paper
  26. Cardiac Inflammation after Local Irradiation Is Influenced by the Kallikrein-Kinin System · Vijayalakshmi Sridharan · 2012 · 36 citations · Cited by this paper
  27. Vascular endothelial growth factor regulation of endothelial nitric oxide synthase phosphorylation is involved in isoflurane cardiac preconditioning · Yanan Liu · 2018 · 35 citations · Cited by this paper
  28. Investigation of microRNA Expression Profiles Associated with Human Alcoholic Cardiomyopathy · Ling Jing · 2015 · 32 citations · Cited by this paper
  29. MiR-21 mediates the protection of kaempferol against hypoxia/reoxygenation-induced cardiomyocyte injury via promoting Notch1/PTEN/AKT signaling pathway · Jinxi Huang · 2020 · 32 citations · Cited by this paper
  30. Hypoxia/reoxygenation-induced upregulation of miRNA-542-5p aggravated cardiomyocyte injury by repressing autophagy · Fei Wang · 2021 · 28 citations · Cited by this paper
  31. miR-194-5p protects against myocardial ischemia/reperfusion injury via MAPK1/PTEN/AKT pathway · Qiufeng Zhang · 2021 · 27 citations · Cited by this paper
  32. MicroRNA profiling of platelets from immune thrombocytopenia and target gene prediction · Gang Deng · 2017 · 24 citations · Cited by this paper
  33. Plantamajoside protects H9c2 cells against hypoxia/reoxygenation-induced injury through regulating the akt/Nrf2/HO-1 and NF-κB signaling pathways · Guangwei Zeng · 2020 · 24 citations · Cited by this paper
  34. Extracorporeal Cardiac Shock Wave-Induced Exosome Derived From Endothelial Colony-Forming Cells Carrying miR-140-3p Alleviate Cardiomyocyte Hypoxia/Reoxygenation Injury via the PTEN/PI3K/AKT Pathway · Dan Yang · 2022 · 20 citations · Cited by this paper
  35. Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3 · Kang Zhou · 2020 · 19 citations · Cited by this paper
  36. LOXL1-AS1 Aggravates Myocardial Ischemia/Reperfusion Injury Through the miR-761/PTEN Axis · Wenhua He · 2023 · 13 citations · Cited by this paper
  37. Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway · Eddie Tam · 2024 · 13 citations · Cited by this paper
  38. miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis · Zhiyu Zhao · 2025 · 11 citations · Cited by this paper
  39. Isoflurane alleviates hypoxia/reoxygenation induced myocardial injury by reducing miR-744 mediated SIRT6 · Guoqing Chen · 2021 · 10 citations · Cited by this paper

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