Research map: Integrated In Vivo and In Silico Approaches for Targeting JAK2/STAT3/SOCS3: Repurposing Boeravinone B and Resveratrol as Chemopreventive Agents in Colon Cancer Back to the article
Papers in this map Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries · Hyuna Sung · 2021 · 114646 citations · Cited by this paperIdentification of Selective Small Molecule Modulators of mRNA Processing Using a Multiplexed QuantiGene High-Throughput Screening Platform · 2025 · RelatedcytoHubba: identifying hub objects and sub-networks from complex interactome · Chia-Hao Chin · 2014 · 7035 citations · Cited by this paperNeprilysin Inhibitor and Angiotensin Receptor Blocker Attenuate Ischemic Brain Injury: Unveiling the Kinin-Mediated Pathway · 2026 · RelatedImmunotherapy in colorectal cancer: rationale, challenges and potential · Karuna Ganesh · 2019 · 2093 citations · Cited by this paperPrecision Targeting in Gastric Cancer: AI-Driven Discovery of MET, ADORA2A, CDK5R1, and ADORA1 · 2025 · RelatedDietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action · Mithun Rudrapal · 2022 · 1081 citations · Cited by this paperIdentification of Broad-Spectrum Inhibitors Targeting Multiple Amyloidogenic Proteins Using Functional Group-Based Virtual Screening · 2026 · RelatedBioavailability of resveratrol · Thomas Walle · 2011 · 1043 citations · Cited by this paperDecoding Cholesterol Metabolic Regulation by Naotai Formula in Stroke Management: An Integrated Network Pharmacology and Mendelian Randomization Approach · 2026 · RelatedNCCN Guidelines Insights: Colon Cancer, Version 2.2018 · Al B. Benson · 2018 · 1043 citations · Cited by this paperLetter: New Horizons in Biomarker Discovery: Assay Technologies for Personalized Drug Development · 2025 · RelatedComprehensive evaluation of ten docking programs on a diverse set of protein–ligand complexes: the prediction accuracy of sampling power and scoring power · Zhe Wang · 2016 · 994 citations · Cited by this paperIdentification of Potential Molecular Targets of Doxorubicin for Application in Skin Cancer: A Network Pharmacology and Molecular Docking Perspective · 2025 · RelatedCurcumin, a component of golden spice: From bedside to bench and back · Sahdeo Prasad · 2014 · 865 citations · Cited by this paperAdvances in Capsaicin-Based Nanocarriers: Bridging Mechanistic Insights with Therapeutic Potential and Clinical Outcomes · 2025 · RelatedNatural Polyphenols for Prevention and Treatment of Cancer · Yue Zhou · 2016 · 749 citations · Cited by this paperElucidating Genetic and Immunological Pathways Mediated by Sodium-Glucose Transporter 2 Inhibitors in Reducing Gout Risk: A Two-Step Mendelian Randomization Study · 2025 · RelatedProperties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans · Juan Pablo Gambini · 2015 · 741 citations · Cited by this paperEffectiveness and Safety of Immune Checkpoint Inhibitors in Colorectal Cancer: A Systematic Review of Real-World Studies · 2025 · RelatedThe Multifaceted Role of Curcumin in Cancer Prevention and Treatment · Muthu Kumaraswamy Shanmugam · 2015 · 511 citations · Cited by this paperVariability in docking success rates due to dataset preparation · Christopher R. Corbeil · 2012 · 481 citations · Cited by this paperHealth Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review · Xiao Meng · 2020 · 391 citations · Cited by this paperTargeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution · Uddalak Bharadwaj · 2020 · 320 citations · Cited by this paperResveratrol in Medicinal Chemistry: A Critical Review of its Pharmacokinetics, Drug-Delivery, and Membrane Interactions · Ana Rute Neves · 2012 · 312 citations · Cited by this paperResveratrol and cellular mechanisms of cancer prevention · Yogeshwer Shukla · 2011 · 272 citations · Cited by this paperCytoscape stringApp 2.0: Analysis and Visualization of Heterogeneous Biological Networks · Nadezhda T. Doncheva · 2022 · 247 citations · Cited by this paperEnhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution? · James M. Smoliga · 2014 · 229 citations · Cited by this paperAmeliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic β‐cell dysfunction in streptozotocin‐nicotinamide‐induced diabetic rats · Palsamy Periyasamy · 2010 · 197 citations · Cited by this paperResveratrol ameliorates podocyte damage in diabetic mice via SIRT1/PGC‐1α mediated attenuation of mitochondrial oxidative stress · Tao Zhang · 2018 · 150 citations · Cited by this paperThe Potential Use of Resveratrol for Cancer Prevention · Dominique Vervandier‐Fasseur · 2019 · 145 citations · Cited by this paperThe Effects of Resveratrol in the Treatment of Metabolic Syndrome · Chih‐Yao Hou · 2019 · 136 citations · Cited by this paper(−)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway · Yue Chen · 2017 · 135 citations · Cited by this paperDocking-Based Virtual Screening Using PyRx Tool: Autophagy Target Vps34 as a Case Study · Sree Karani Kondapuram · 2021 · 114 citations · Cited by this paperAntitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer · Omar H. Alobaedi · 2017 · 108 citations · Cited by this paperResveratrol: Challenges in Translation to the Clinic — A Critical Discussion · Lalita Subramanian · 2010 · 104 citations · Cited by this paperThe Efficacy of Immune Checkpoint Inhibitors in Microsatellite Stable Colorectal Cancer: A Systematic Review · Deniz Can Güven · 2024 · 78 citations · Cited by this paperThe science of resveratrol, formulation, pharmacokinetic barriers and its chemotherapeutic potential · Imogen Robertson · 2022 · 74 citations · Cited by this paperResveratrol improved mitochondrial biogenesis by activating SIRT1/PGC-1α signal pathway in SAP · Shukun Wu · 2024 · 66 citations · Cited by this paperSource: OpenAlex (CC0)