Research map: Inhibition of fibrinolysis in vitro by supraphysiological doses of small molecule FXIa inhibitors

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Papers in this map

  1. A Study of the Mechanism of Inhibition of Fibrinolysis by Activated Thrombin-activable Fibrinolysis Inhibitor · Wei Qiang Wang · 1998 · 389 citations · Cited by this paper
  2. Multigene panel analysis of connective tissue and vascular genes in patients with a bleeding disorder of unknown cause or a cerebrovascular event · 2026 · Related
  3. Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis · Peter A. von dem Borne · 1995 · 296 citations · Cited by this paper
  4. Call to action: identifying an underlying bleeding disorder in adolescents with heavy menstrual bleeding · 2026 · Related
  5. Thrombin-mediated activation of factor XI results in a thrombin-activatable fibrinolysis inhibitor-dependent inhibition of fibrinolysis. · Peter A. von dem Borne · 1997 · 234 citations · Cited by this paper
  6. EP1T3_7 Impact of a Regional Plasma-PBM Strategy on Clinical Consumption and Economic Optimization of the Toll Manufacturing Model: A 10-Year Analysis (2016-2025) · 2026 · Related
  7. Activation of plasminogen by human plasma kallikrein · Robert W. Colman · 1969 · 219 citations · Cited by this paper
  8. EP3T3_2 Implementation of a hospital-wide pathway for patients refusing blood components: early experience from a tertiary centre · 2026 · Related
  9. Coagulation-dependent inhibition of fibrinolysis: role of carboxypeptidase-U and the premature lysis of clots from hemophilic plasma · GJ Jr Broze · 1996 · 213 citations · Cited by this paper
  10. EP2T7_1 Early use of Tranexamic Acid in postpartum hemorrhage · 2026 · Related
  11. Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A · Ton Lisman · 2002 · 156 citations · Cited by this paper
  12. EP1T7_6 Clinical Impact of Multimodal Patient Blood Management in Urgent Cardiac Surgery for Infective Endocarditis: A Retrospective Cohort Study · 2026 · Related
  13. The Defective Down Regulation of Fibrinolysis in Haemophilia A Can Be Restored by Increasing the TAFI Plasma Concentration · Laurent O. Mosnier · 2001 · 125 citations · Cited by this paper
  14. Venous Thromboembolism in China: Epidemiology, Management Strategies, and Future Directions · 2026 · Related
  15. Dabigatran enhances clot susceptibility to fibrinolysis by mechanisms dependent on and independent of thrombin‐activatable fibrinolysis inhibitor · Concetta Tiziana Ammollo · 2010 · 110 citations · Cited by this paper
  16. Disseminated Intravascular Coagulation in Chimeric Antigen Receptor T-Cell Therapy: A Six-Year Nationwide Analysis of Clinical Outcomes and Healthcare Resource Utilization in Patients with Hematologic Malignancies · 2026 · Related
  17. Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy · Andrew K. Dilger · 2021 · 104 citations · Cited by this paper
  18. Evaluation and application of automated quality control in clinical coagulation testing · 2026 · Related
  19. Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa · Stefan Heitmeier · 2022 · 97 citations · Cited by this paper
  20. EP1T4_7 Prothrombotic phenotype after severe trauma in ICU patients: serial ROTEM reveals a shift over 72 hours · 2026 · Related
  21. Abnormal plasma clot structure and stability distinguish bleeding risk in patients with severe factor XI deficiency · Michal Zucker · 2014 · 93 citations · Cited by this paper
  22. Factor XI inhibitors for the prevention and treatment of venous and arterial thromboembolism · Davide Capodanno · 2025 · 43 citations · Cited by this paper
  23. Venous thrombosis and tissue plasminogen activator release deficiency · G. M. Pattassi · 1991 · 23 citations · Cited by this paper
  24. Laboratory Evaluation of Interferences Associated with Factor XIa Inhibitors Asundexian and Milvexian in Routine Coagulation Assays · Gavin T. Buckley · 2024 · 8 citations · Cited by this paper
  25. Real-Time Imaging of Platelet-Initiated Plasma Clot Formation and Lysis Unveils Distinct Impacts of Anticoagulants · Yuko Suzuki · 2025 · 7 citations · Cited by this paper
  26. Effect of heparins, direct oral anticoagulants, and factor XII/factor XI inhibitors on catheter-initiated thrombin generation in platelet-rich plasma: an in vitro study · Michael J Hardy · 2025 · 7 citations · Cited by this paper
  27. Profibrinolytic effects of rivaroxaban are mediated by thrombin-activatable fibrinolysis inhibitor and are attenuated by a naturally occurring stabilizing mutation in enzyme · Justin J. W. Garabon · 2023 · 6 citations · Cited by this paper
  28. Congruent identification of imbalanced fibrinolysis by 2 distinct clot lysis time assays · Ellen G. Driever · 2023 · 5 citations · Cited by this paper
  29. DOAC–Stop reverses the anticoagulant effect of asundexian and milvexian · Ella K Fitzpatrick · 2025 · 5 citations · Cited by this paper

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