Research map: Delivery Strategies for Oncolytic Viruses in Gastrointestinal Cancers: Progress, Mechanisms and Clinical Translations

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  1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries · Hyuna Sung · 2021 · 114646 citations · Cited by this paper
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  5. Oncolytic Immunotherapy: Dying the Right Way is a Key to Eliciting Potent Antitumor Immunity · Zong Sheng Guo · 2014 · 285 citations · Cited by this paper
  6. The Burden of HPV35 in African Cervical Pathologies: Prevalence, Contributing Factors, and Vaccine Prospects · 2026 · Related
  7. Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade · Shinsuke Nakao · 2020 · 192 citations · Cited by this paper
  8. Human Sapovirus in the Post‐Rotavirus Vaccine Era: From an Overlooked Gastroenteritis Pathogen to a Target for Precision Surveillance · 2026 · Related
  9. Oncolytic virotherapy-mediated anti-tumor response: a single-cell perspective · Egle Ramelyte · 2021 · 110 citations · Cited by this paper
  10. Possible Effects of C‐Reactive Protein in the Central Nervous System During Venezuelan Equine Encephalitis Virus Infection · 2026 · Related
  11. Clinical Application of Oncolytic Viruses: A Systematic Review · Mary A. Cook · 2020 · 98 citations · Cited by this paper
  12. Synergistic Oncogenesis Cooperative Role of Epstein Barr Virus and Human Papillomavirus in Cancer Progression · 2026 · Related
  13. Immunogenic cell death: The cornerstone of oncolytic viro-immunotherapy · Lalitha Palanivelu · 2023 · 81 citations · Cited by this paper
  14. Potential Relationship Between Cytomegalovirus and Cardiovascular Disease: Evidence From Observational Studies · 2026 · Related
  15. Oncolytic adenovirus expressing relaxin (YDC002) enhances therapeutic efficacy of gemcitabine against pancreatic cancer · Kyung Hee Jung · 2017 · 80 citations · Cited by this paper
  16. Oncovirus‐Driven Endothelial Plasticity: Endothelial‐to‐Mesenchymal Transition as a Hijacked Pathway in Oncoviral Cardiovascular Pathogenesis · 2026 · Related
  17. Bi- and Tri-Specific T Cell Engager-Armed Oncolytic Viruses: Next-Generation Cancer Immunotherapy · Zong Sheng Guo · 2020 · 75 citations · Cited by this paper
  18. Kyasanur Forest Disease: Advances in Experimental Animal Models, Immune Assays, and Challenges in Vaccine Development · 2026 · Related
  19. Cytokine Conditioning Enhances Systemic Delivery and Therapy of an Oncolytic Virus · Elizabeth J. Ilett · 2014 · 73 citations · Cited by this paper
  20. Qualitative Modulation of Pattern Recognition Receptor Sensing in Human Oncoviral Infections: Shared and Virus‐Specific Innate Immune Strategies · 2026 · Related
  21. Oncolytic VSV Primes Differential Responses to Immuno-oncology Therapy · Nicholas M. Durham · 2017 · 66 citations · Cited by this paper
  22. A hydrogel matrix prolongs persistence and promotes specific localization of an oncolytic adenovirus in a tumor by restricting nonspecific shedding and an antiviral immune response · Bo‐Kyeong Jung · 2017 · 59 citations · Cited by this paper
  23. Systemic administration of human mesenchymal stromal cells infected with polymer-coated oncolytic adenovirus induces efficient pancreatic tumor homing and infiltration · Youjin Na · 2019 · 55 citations · Cited by this paper
  24. An oncolytic virus–delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment · Kristin DePeaux · 2023 · 51 citations · Cited by this paper
  25. Bacterial-Mediated Knockdown of Tumor Resistance to an Oncolytic Virus Enhances Therapy · Michelle A. Cronin · 2014 · 49 citations · Cited by this paper
  26. Effects of nanoparticle coatings on the activity of oncolytic adenovirus–magnetic nanoparticle complexes · Nittaya Tresilwised · 2011 · 48 citations · Cited by this paper
  27. Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles · Yoshihiko Kakiuchi · 2021 · 45 citations · Cited by this paper
  28. Oncolytic Reovirus Inhibits Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in a TLR3-Dependent Manner · Yuki Katayama · 2018 · 44 citations · Cited by this paper
  29. Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus · Mark S. Ferguson · 2020 · 43 citations · Cited by this paper
  30. Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer · Takeshi Koujima · 2020 · 43 citations · Cited by this paper
  31. Hydrogel-based co-delivery of CIK cells and oncolytic adenovirus armed with IL12 and IL15 for cancer immunotherapy · Yanan Du · 2022 · 43 citations · Cited by this paper
  32. Combination of interferon-expressing oncolytic adenovirus with chemotherapy and radiation is highly synergistic in hamster model of pancreatic cancer · Amanda O. Salzwedel · 2018 · 41 citations · Cited by this paper
  33. Novel Chimeric Immuno-Oncolytic Virus CF33-hNIS-antiPDL1 for the Treatment of Pancreatic Cancer · Yanghee Woo · 2020 · 41 citations · Cited by this paper
  34. The Dilemma of HSV-1 Oncolytic Virus Delivery: The Method Choice and Hurdles · Guijin Tang · 2023 · 41 citations · Cited by this paper
  35. Local delivery of a cancer-favoring oncolytic vaccinia virus via poly (lactic-co-glycolic acid) nanofiber for theranostic purposes · Narayanasamy Badrinath · 2018 · 39 citations · Cited by this paper
  36. A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression · Susanne Gray Warner · 2019 · 39 citations · Cited by this paper
  37. Evolutionary cancer-favoring engineered vaccinia virus for metastatic hepatocellular carcinoma · So Young Yoo · 2017 · 38 citations · Cited by this paper
  38. Newcastle disease virus mediates pancreatic tumor rejection via NK cell activation and prevents cancer relapse by prompting adaptive immunity · Theresa Schwaiger · 2017 · 37 citations · Cited by this paper
  39. Systemic Delivery of Oncolytic Adenovirus to Tumors Using Tumor-Infiltrating Lymphocytes as Carriers · João Manuel Santos · 2021 · 35 citations · Cited by this paper

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