Research map: Single Cell Proteomics to Spatial Multiomics in Cardiovascular Disease: Foundations, Technologies, and Biological Insights

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Papers in this map

  1. limma powers differential expression analyses for RNA-sequencing and microarray studies · Matthew E. Ritchie · 2015 · 44581 citations · Cited by this paper
  2. Defining Actionable Cell States in Cardiovascular Disease Through Single-Cell and Spatial Technologies · Sarah J. Parker · 2026 · 1 citation · Cites this paper
  3. Small Extracellular Vesicles From Cardiomyocytes Activate Microglia Aggravating HFpEF · 2026 · Related
  4. Fast unfolding of communities in large networks · Vincent D. Blondel · 2008 · 21908 citations · Cited by this paper
  5. Contractility Drives Cardiomyocyte Maturation and the Response to Nanopatterns · 2026 · Related
  6. Integrating single-cell transcriptomic data across different conditions, technologies, and species · Andrew W. Butler · 2018 · 15128 citations · Cited by this paper
  7. Monocyte Dll4 Contributes to Systemic Inflammation in People Living With HIV · 2026 · Related
  8. SCANPY: large-scale single-cell gene expression data analysis · F. Alexander Wolf · 2018 · 9933 citations · Cited by this paper
  9. Lipoproteins in Cardiovascular Disease: Building on Successes to Meet Future Challenges · 2026 · Related
  10. The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells · Cole Trapnell · 2014 · 8195 citations · Cited by this paper
  11. Epicardial Fat Drives Macrophage Response in Atrial Cardiomyopathy · 2026 · Related
  12. Dimensionality reduction for visualizing single-cell data using UMAP · Étienne Becht · 2018 · 5917 citations · Cited by this paper
  13. Inflammasome-Primed Neutrophils Aggravate Atherosclerosis in Cigarette Smoking · 2026 · Related
  14. Molecular Imaging of Biological Samples: Localization of Peptides and Proteins Using MALDI-TOF MS · Richard M. Caprioli · 1997 · 2263 citations · Cited by this paper
  15. Antibody E06 and the Role of Oxidized Phospholipids in Atherogenesis and Inflammation · 2026 · Related
  16. The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030 · Birgit Vogel · 2021 · 1507 citations · Cited by this paper
  17. Glycine Receptor α2 Mediates Vasodilation via Endothelial eNOS Signaling · 2026 · Related
  18. Cardiac fibrosis · Nikolaos G. Frangogiannis · 2020 · 1231 citations · Cited by this paper
  19. Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies · Suowen Xu · 2021 · 1168 citations · Cited by this paper
  20. SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation · Bogdan Budnik · 2018 · 887 citations · Cited by this paper
  21. Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells · Ying Zhu · 2018 · 634 citations · Cited by this paper
  22. Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023 · Benjamin A. Stark · 2025 · 612 citations · Cited by this paper
  23. Sublimation as a method of matrix application for mass spectrometric imaging · Joseph A. Hankin · 2007 · 598 citations · Cited by this paper
  24. Deep Visual Proteomics defines single-cell identity and heterogeneity · Andreas Mund · 2022 · 586 citations · Cited by this paper
  25. FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry · Andrew Palmer · 2016 · 543 citations · Cited by this paper
  26. Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2 · Harrison Specht · 2021 · 538 citations · Cited by this paper
  27. Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure · Andrew L. Koenig · 2022 · 491 citations · Cited by this paper
  28. Parallel Accumulation–Serial Fragmentation (PASEF): Multiplying Sequencing Speed and Sensitivity by Synchronized Scans in a Trapped Ion Mobility Device · Florian Meier · 2015 · 478 citations · Cited by this paper
  29. Ion formation mechanisms in UV-MALDI · Richard Knochenmuss · 2006 · 450 citations · Cited by this paper
  30. MSiReader: An Open-Source Interface to View and Analyze High Resolving Power MS Imaging Files on Matlab Platform · Guillaume Robichaud · 2013 · 406 citations · Cited by this paper
  31. Gender medicine: effects of sex and gender on cardiovascular disease manifestation and outcomes · Vera Regitz‐Zagrosek · 2022 · 387 citations · Cited by this paper
  32. Mass spectrometry imaging with laser-induced postionization · Jens Soltwisch · 2015 · 385 citations · Cited by this paper
  33. Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry · Mark Reid Groseclose · 2007 · 380 citations · Cited by this paper
  34. SpaceM reveals metabolic states of single cells · Luca Rappez · 2021 · 373 citations · Cited by this paper
  35. Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition · Ulises H. Guzmán · 2024 · 364 citations · Cited by this paper
  36. Quantitative single-cell proteomics as a tool to characterize cellular hierarchies · Erwin M. Schoof · 2021 · 363 citations · Cited by this paper
  37. Molecular imaging by mass spectrometry — looking beyond classical histology · Kristina Schwamborn · 2010 · 356 citations · Cited by this paper
  38. Profiling metabolites and peptides in single cells · Stanislav S. Rubakhin · 2011 · 350 citations · Cited by this paper
  39. Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging · Marta Murgia · 2017 · 330 citations · Cited by this paper

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