Research map: Genetic polymorphism of CYP2C19 in recurrent ischemic stroke patients: prevalence and role in secondary prevention

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Papers in this map

  1. Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 · Valery L. Feigin · 2021 · 8115 citations · Cited by this paper
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  14. Clinical characteristics and outcomes of Guillain Barre syndrome: a hospital-based study at Benha university · 2026 · Related
  15. Cardiovascular Risk in Clopidogrel-Treated Patients According to Cytochrome P450 2C19*2 Loss-of-Function Allele or Proton Pump Inhibitor Coadministration · Jean‐Sébastien Hulot · 2010 · 383 citations · Cited by this paper
  16. Effect of body positions on outcomes of single-pulse transcranial magnetic stimulation · 2026 · Related
  17. Risk and Secondary Prevention of Stroke Recurrence · Clare Flach · 2020 · 351 citations · Cited by this paper
  18. Artificial intelligence in rare neurological diseases: a scoping review of the evidence landscape and framework for foundation model integration · 2026 · Related
  19. Clopidogrel Pharmacogenetics · Naveen L. Pereira · 2019 · 229 citations · Cited by this paper
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  21. Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel · Michel Zabalza · 2011 · 180 citations · Cited by this paper
  22. Ticagrelor plus aspirin versus clopidogrel plus aspirin for platelet reactivity in patients with minor stroke or transient ischaemic attack: open label, blinded endpoint, randomised controlled phase II trial · Yilong Wang · 2019 · 144 citations · Cited by this paper
  23. CYP2C19 Genetic Testing for Oral P2Y12 Inhibitor Therapy: A Scientific Statement From the American Heart Association · Naveen L. Pereira · 2024 · 121 citations · Cited by this paper
  24. CYP2C19 Polymorphisms and Antiplatelet Effects of Clopidogrel in Acute Ischemic Stroke in China · Dongmei Jia · 2013 · 106 citations · Cited by this paper
  25. Clinical implementation of rapid CYP2C19 genotyping to guide antiplatelet therapy after percutaneous coronary intervention · Larisa H. Cavallari · 2018 · 64 citations · Cited by this paper
  26. Recurrent Stroke, Myocardial Infarction, and Major Vascular Events during the First Year after Acute Ischemic Stroke: The Multicenter Prospective Observational Study about Recurrence and Its Determinants after Acute Ischemic Stroke I · Kyusik Kang · 2015 · 61 citations · Cited by this paper
  27. Rate and Determinants of Recurrence at 1 Year and 5 Years After Stroke in a Low-Income Population in Rural China · Jing Han · 2020 · 61 citations · Cited by this paper
  28. Influence of Genetic Polymorphisms on Clopidogrel Response and Clinical Outcomes in Patients with Acute Ischemic Stroke CYP2C19 Genotype on Clopidogrel Response · Yan Han · 2015 · 45 citations · Cited by this paper
  29. Long-Term Risk of Stroke After Transient Ischemic Attack or Minor Stroke · Faizan Khan · 2025 · 38 citations · Cited by this paper
  30. Anti-platelet Therapy Resistance – Concept, Mechanisms and Platelet Function Tests in Intensive Care Facilities · Alina Mărginean · 2016 · 35 citations · Cited by this paper
  31. Cost-effectiveness of CYP2C19 genotyping to guide antiplatelet therapy for acute minor stroke and high-risk transient ischemic attack · Zeling Cai · 2021 · 35 citations · Cited by this paper
  32. Economic Evaluations of CYP2C19 Genotype-Guided Antiplatelet Therapy Compared to the Universal Use of Antiplatelets in Patients With Acute Coronary Syndrome: A Systematic Review · Sawsan AlMukdad · 2020 · 34 citations · Cited by this paper
  33. Influence of CYP2C19 loss-of-function variants on the antiplatelet effects and cardiovascular events in clopidogrel-treated Chinese patients undergoing percutaneous coronary intervention · Jianjun Zou · 2012 · 30 citations · Cited by this paper
  34. Feasibility and Implementation of CYP2C19 Genotyping in Patients Using Antiplatelet Therapy · Thomas O. Bergmeijer · 2018 · 29 citations · Cited by this paper
  35. Global, regional, and national trends in ischaemic stroke burden and risk factors among adults aged 20 + years (1990–2021): a systematic analysis of data from the Global Burden of Disease study 2021 with projections into 2050 · Sibo Liu · 2025 · 28 citations · Cited by this paper
  36. The association of CYP2C19 LoF alleles with adverse clinical outcomes in stroke patients taking clopidogrel: An updated meta‐analysis · Mohitosh Biswas · 2024 · 25 citations · Cited by this paper
  37. Impact of CYP2C19 Genotype Status on Clinical Outcomes in Patients with Symptomatic Coronary Artery Disease, Stroke, and Peripheral Arterial Disease: A Systematic Review and Meta-Analysis · Dominique P.M.S.M. Maas · 2024 · 18 citations · Cited by this paper
  38. Risk of stroke in CYP2C19 LoF polymorphism carrier coronary artery disease patients undergoing clopidogrel therapy: An ethnicity-based updated meta-analysis · Sarah Jafrin · 2021 · 17 citations · Cited by this paper
  39. A novel approach of platelet function test for prediction of attenuated response to clopidogrel · Erzsébet Ezer · 2019 · 16 citations · Cited by this paper

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