Research map: Combined use of insulin eye drops and cross-linked hyaluronic acid canalicular gel for the management of severe neurotrophic keratopathy

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  1. Anatomy and physiology of the cornea · Derek W. DelMonte · 2011 · 878 citations · Cited by this paper
  2. Recurrent aqueous misdirection following intraluminal ripcord removal from a Paul Glaucoma Implant · 2026 · Related
  3. Neurotrophic keratitis: current challenges and future prospects · Piera Versura · 2018 · 182 citations · Cited by this paper
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  5. Blood derived eye drops for the treatment of cornea and ocular surface diseases · Giuseppe Giannaccare · 2017 · 149 citations · Cited by this paper
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  9. Insulin, Not Leptin, Promotes In Vitro Cell Migration to Heal Monolayer Wounds in Human Corneal Epithelium · Lynne J. Shanley · 2004 · 90 citations · Cited by this paper
  10. Spontaneous closure of a full-thickness macular hole in highly myopic eye: A case report · 2026 · Related
  11. Comparison of the efficacy of topical insulin with autologous serum eye drops in persistent epithelial defects of the cornea · David Díaz‐Valle · 2021 · 73 citations · Cited by this paper
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  13. Topical insulin for refractory persistent corneal epithelial defects · David Díaz‐Valle · 2020 · 63 citations · Cited by this paper
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  15. Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling · Shuo Yang · 2020 · 59 citations · Cited by this paper
  16. Autologous Tenon's capsule for post-vitrectomy macular hole closure: A case report · 2026 · Related
  17. Topical Insulin—Utility and Results in Refractory Neurotrophic Keratopathy in Stages 2 and 3 · Ricardo Machado Soares · 2021 · 46 citations · Cited by this paper
  18. Healing of Chemical Injury–Related Persistent Corneal Epithelial Defects With Topical Insulin · Shafi Balal · 2022 · 31 citations · Cited by this paper
  19. Randomized Clinical Trial of Topical Insulin Versus Artificial Tears for Healing Rates of Iatrogenic Corneal Epithelial Defects Induced During Vitreoretinal Surgery in Diabetics · Aina Malindri Dasrilsyah · 2023 · 31 citations · Cited by this paper
  20. Combined Use of Therapeutic Hyper-CL Soft Contact Lens and Insulin Eye Drops for the Treatment of Recalcitrant Neurotrophic Keratopathy · Giuseppe Giannaccare · 2023 · 19 citations · Cited by this paper
  21. Clinical and instrumental assessment of the corneal healing in moderate and severe neurotrophic keratopathy treated with rh-NGF (Cenegermin) · Anna Maria Roszkowska · 2022 · 17 citations · Cited by this paper
  22. Comparison of Persistent Epithelial Defect Treatment With Sutureless Cryopreserved and Dehydrated Amniotic Membrane · Shawn S. Sell · 2022 · 15 citations · Cited by this paper
  23. Current and Emerging Therapeutic Strategies for the Management of Neurotrophic Keratitis · Javier Lacorzana · 2025 · 8 citations · Cited by this paper
  24. Effectiveness and safety of a novel crosslinked hyaluronate canalicular gel occlusive device for dry eye · Mark Packer · 2024 · 7 citations · Cited by this paper
  25. Comparison of Amniotic Membrane Extract and Insulin Eye Drops for the Management of Persistent Epithelial Defects: A Multicenter Retrospective Study · Matilde Buzzi · 2025 · 4 citations · Cited by this paper
  26. Current and emerging medical treatment options for corneal persistent epithelial defects · Filippo Lixi · 2026 · 3 citations · Cited by this paper
  27. Topical Insulin for Corneal Persistent Epithelial Defects: A Multicenter Retrospective Study · Filippo Lixi · 2026 · 1 citation · Cited by this paper

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