Research map: The therapy-induced senescence-associated secretory phenotype and epithelial-mesenchymal transition Axis in ovarian cancer: molecular mechanisms and therapeutic opportunities

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  1. The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression · Jean‐Philippe Coppé · 2010 · 5342 citations · Cited by this paper
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  24. mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype · Nicolás Herranz · 2015 · 812 citations · Cited by this paper
  25. IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis · Matjaž Rokavec · 2014 · 781 citations · Cited by this paper
  26. Non-Cell-Autonomous Tumor Suppression by p53 · Amaia Lujambio · 2013 · 771 citations · Cited by this paper
  27. EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness · Ester Sànchez‐Tilló · 2012 · 524 citations · Cited by this paper
  28. Inducing and exploiting vulnerabilities for the treatment of liver cancer · Cun Wang · 2019 · 440 citations · Cited by this paper
  29. BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance · Nilgun Tasdemir · 2016 · 434 citations · Cited by this paper
  30. Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line · Paola Ortíz-Montero · 2017 · 428 citations · Cited by this paper
  31. Drug repurposing for cancer therapy · Ying Xia · 2024 · 422 citations · Cited by this paper
  32. Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer · Jermaine I Coward · 2011 · 393 citations · Cited by this paper
  33. The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis? · Naoko Ohtani · 2022 · 286 citations · Cited by this paper
  34. Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence · Hubert Fleury · 2019 · 229 citations · Cited by this paper
  35. The Cancer SENESCopedia: A delineation of cancer cell senescence · Fleur Jochems · 2021 · 214 citations · Cited by this paper
  36. SASP: Tumor Suppressor or Promoter? Yes! · Sonia G. Rao · 2016 · 210 citations · Cited by this paper
  37. TGF-β, EMT, and resistance to anti-cancer treatment · Xuecong Wang · 2023 · 174 citations · Cited by this paper
  38. NAMPT Inhibition Suppresses Cancer Stem-like Cells Associated with Therapy-Induced Senescence in Ovarian Cancer · Timothy Nacarelli · 2019 · 164 citations · Cited by this paper
  39. NF-κB Signaling in Ovarian Cancer · Brittney S. Harrington · 2019 · 137 citations · Cited by this paper

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