Research map: A second-hit conceptual framework for pulmonary arterial hypertension in adult congenital heart disease: genetics, hemodynamics, and treat-and-repair

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  1. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension · Marc Humbert · 2022 · 3965 citations · Cited by this paper
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  19. Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension · Benoît Ranchoux · 2015 · 587 citations · Cited by this paper
  20. The COngenital HeARt Disease in adult and Pulmonary Hypertension (COHARD-PH) registry: a descriptive study from single-center hospital registry of adult congenital heart disease and pulmonary hypertension in Indonesia · 2020 · Related
  21. Improved Survival Among Patients With Eisenmenger Syndrome Receiving Advanced Therapy for Pulmonary Arterial Hypertension · Konstantinos Dimopoulos · 2009 · 392 citations · Cited by this paper
  22. Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart disease · Peter M. Engelfriet · 2006 · 391 citations · Cited by this paper
  23. Pulmonary arterial hypertension in congenital heart disease: An epidemiologic perspective from a Dutch registry · M. G. J. Duffels · 2006 · 364 citations · Cited by this paper
  24. Endothelial to Mesenchymal Transition Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension · Robert B. Good · 2015 · 361 citations · Cited by this paper
  25. Endothelial cells in the pathogenesis of pulmonary arterial hypertension · Colin E. Evans · 2021 · 331 citations · Cited by this paper
  26. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex · Brian G. Coon · 2015 · 299 citations · Cited by this paper
  27. Comprehensive Use of Cardiopulmonary Exercise Testing Identifies Adults With Congenital Heart Disease at Increased Mortality Risk in the Medium Term · Ryo Inuzuka · 2011 · 288 citations · Cited by this paper
  28. Fontan-Associated Liver Disease · Juliet A. Emamaullee · 2020 · 277 citations · Cited by this paper
  29. BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease · Kari E. Roberts · 2004 · 264 citations · Cited by this paper
  30. Longer-term bosentan therapy improves functional capacity in Eisenmenger syndrome: Results of the BREATHE-5 open-label extension study · Michael Athanassios Gatzoulis · 2007 · 248 citations · Cited by this paper
  31. Fontan-Associated Liver Disease · Curt J. Daniels · 2017 · 212 citations · Cited by this paper
  32. Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension · Anastasia Gorelova · 2020 · 186 citations · Cited by this paper
  33. Blood Flow Vortices along the Main Pulmonary Artery Measured with MR Imaging for Diagnosis of Pulmonary Hypertension · Gert Reiter · 2014 · 180 citations · Cited by this paper
  34. Predictors of Death in Contemporary Adult Patients With Eisenmenger Syndrome · Aleksander Kempny · 2016 · 169 citations · Cited by this paper
  35. Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease · Na Zhu · 2018 · 168 citations · Cited by this paper
  36. Four-dimensional flow assessment of pulmonary artery flow and wall shear stress in adult pulmonary arterial hypertension: Results from two institutions · Alex J. Barker · 2014 · 148 citations · Cited by this paper
  37. Pulmonary Hypertension in Congenital Heart Disease: A Scientific Statement From the American Heart Association · Pei‐Ni Jone · 2023 · 133 citations · Cited by this paper
  38. Evaluation of Macitentan in Patients With Eisenmenger Syndrome · Michael Athanassios Gatzoulis · 2018 · 132 citations · Cited by this paper
  39. BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension · Iona Cuthbertson · 2023 · 126 citations · Cited by this paper

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