Research map: Autophagy in Osx1-Cre-targeted cells is essential for development, growth, and maintenance of bone

Papers in this map

1. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method · Kenneth J. Livak · 2001 · 185110 citations · Cited by this paper
2. Predictors of clinically meaningful bone mineral density gains with romosozumab: An explainable machine leaning analysis of a real-world cohort · 2025 · Related
3. Integrated analysis of multimodal single-cell data · Yuhan Hao · 2021 · 16919 citations · Cited by this paper
4. Transferrin-dependent uptake and distribution of iron in osteoclast-like cells · 2026 · Related
5. MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data · Greg Finak · 2015 · 3717 citations · Cited by this paper
6. Effectiveness of romosozumab following prior raloxifene treatment in primary osteoporosis: An observational study · 2026 · Related
7. Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee · David W. Dempster · 2012 · 2601 citations · Cited by this paper
8. Integrating intrinsic musculoskeletal pathology and genetics: Recent advances in unravelling the causative factors of adolescent idiopathic scoliosis · 2025 · Related
9. Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice · Masaaki Komatsu · 2005 · 2349 citations · Cited by this paper
10. Simulated microgravity accurately models long-duration spaceflight effects on bone and skeletal muscle in skeletally immature mice · 2025 · Related
11. The machinery of macroautophagy · Yuchen Feng · 2013 · 2129 citations · Cited by this paper
12. Intelligent identification of osteoporosis on hip X-rays using vision transformer · 2026 · Related
13. Autophagy and Aging · David Chaim Rubinsztein · 2011 · 2117 citations · Cited by this paper
14. A comparative analysis of bone mineral density in cerebral palsy and spinal muscular atrophy · 2025 · Related
15. Autophagy maintains stemness by preventing senescence · Laura García‐Prat · 2016 · 1397 citations · Cited by this paper
16. Individualized antiresorptive therapy in fibrous dysplasia and McCune-Albright syndrome: A retrospective cohort study · 2026 · Related
17. Targeting cellular senescence prevents age-related bone loss in mice · Joshua N. Farr · 2017 · 1208 citations · Cited by this paper
18. Cyclin-dependent kinase inhibitor-1 deficiency enhances bone destruction in a mouse model of arthritis · 2025 · Related
19. Autophagy mediates the mitotic senescence transition · Andrew R. J. Young · 2009 · 1106 citations · Cited by this paper
20. Sost deficiency leads to greater bone vascular porosity, but similar osteocyte lacunar properties with increasing age · 2026 · Related
21. p62 at the Crossroads of Autophagy, Apoptosis, and Cancer · Jorge Moscat · 2009 · 1088 citations · Cited by this paper
22. Distinct roles for Hedgehog and canonical Wnt signaling in specification,differentiation and maintenance of osteoblast progenitors · Stephen J. Rodda · 2006 · 1019 citations · Cited by this paper
23. Autophagy-Independent Functions of the Autophagy Machinery · Lorenzo Galluzzi · 2019 · 889 citations · Cited by this paper
24. Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods · Leif Väremo · 2013 · 758 citations · Cited by this paper
25. Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis · Rui-Ming Liu · 2015 · 716 citations · Cited by this paper
26. Age-Related Changes in Trabecular Architecture Differ in Female and Male C57BL/6J Mice · Vaida Glatt · 2007 · 618 citations · Cited by this paper
27. Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines · Robert L. Jilka · 1998 · 583 citations · Cited by this paper
28. Identification of Senescent Cells in the Bone Microenvironment · Joshua N. Farr · 2016 · 568 citations · Cited by this paper
29. Inhibition of Osteoblast Differentiation by Tumor Necrosis Factor-α* · Linda C. Gilbert · 2000 · 556 citations · Cited by this paper
30. TGF‐β‐induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation · Tamara N. Alliston · 2001 · 531 citations · Cited by this paper
31. Autophagy in osteoblasts is involved in mineralization and bone homeostasis · Marie Nollet · 2014 · 437 citations · Cited by this paper
32. Autophagy controls mesenchymal stem cell properties and senescence during bone aging · Yang Ma · 2017 · 365 citations · Cited by this paper
33. Mitochondrial spare respiratory capacity: Mechanisms, regulation, and significance in non‐transformed and cancer cells · Philippe Marchetti · 2020 · 346 citations · Cited by this paper
34. Endogenous TGF‐β signaling suppresses maturation of osteoblastic mesenchymal cells · Shingo Maeda · 2004 · 342 citations · Cited by this paper
35. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production · Claudia Capparelli · 2012 · 234 citations · Cited by this paper
36. CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis · Claudia Capparelli · 2012 · 230 citations · Cited by this paper
37. Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation · Fei Liu · 2013 · 229 citations · Cited by this paper
38. Defective autophagy in osteoblasts induces endoplasmic reticulum stress and causes remarkable bone loss · Huixia Li · 2018 · 223 citations · Cited by this paper
39. Suppression of Autophagy in Osteocytes Mimics Skeletal Aging · Melda Onal · 2013 · 204 citations · Cited by this paper

Source: OpenAlex (CC0)