Research map: Micro- and Nanoplastics in Cardiovascular Toxicology: Human Tissue Detection, Clinical Phenotypes, and Adverse Outcome Signals

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Papers in this map

  1. Discovery and quantification of plastic particle pollution in human blood · Heather A. Leslie · 2022 · 3894 citations · Cited by this paper
  2. Non-canonical PPARα Agonism by Arjunolic Acid Mitigates Cardiomyocyte PANoptosis Through a Novel PPARα/CRYAB/IKKα Axis During Pathological Cardiac Hypertrophy · 2026 · Related
  3. Pathology of the Vulnerable Plaque · Renu Virmani · 2006 · 2331 citations · Cited by this paper
  4. Interpretable Machine Learning in Heavy Metal-Associated Cardiovascular and Metabolic Disease: A Review of Current Methodologies, Toxicological Insights, and Clinical Implications · 2026 · Related
  5. Microplastics and Nanoplastics in Atheromas and Cardiovascular Events · Raffaele Marfella · 2024 · 1162 citations · Cited by this paper
  6. Drug-Induced Noninfectious Myocarditis/Pericarditis: A Real-World Pharmacovigilance Study Using the FAERS Database · 2026 · Related
  7. Detection of Various Microplastics in Patients Undergoing Cardiac Surgery · Yunxiao Yang · 2023 · 571 citations · Cited by this paper
  8. Methyltransferase METTL1 Upregulates USF2 in a m7G-Dependent Manner to Accelerate Septic Cardiomyopathy by Inactivating PINK1/Parkin-Mediated Mitophagy · 2026 · Related
  9. Reporting Guidelines to Increase the Reproducibility and Comparability of Research on Microplastics · Win Cowger · 2020 · 462 citations · Cited by this paper
  10. Tnxb Alleviates Myocardial Ischemia-Reperfusion Injury Through Facilitating Akt-Dependent Endothelial Cell Survival and Angiogenesis in Mice · 2026 · Related
  11. Sampling and Quality Assurance and Quality Control: A Guide for Scientists Investigating the Occurrence of Microplastics Across Matrices · Susanne M. Brander · 2020 · 383 citations · Cited by this paper
  12. GLI1 Promotes Hypoxia Induced Pyroptosis of PASMCs and Aggravates Pulmonary Arterial Hypertension in Rats by Upregulating HDAC1 Expression · 2026 · Related
  13. Microplastics in human blood: Polymer types, concentrations and characterisation using μFTIR · Sophie V. L. Leonard · 2024 · 275 citations · Cited by this paper
  14. E-cigarette Aerosol Containing Nicotine Increases Aortic Stiffness in Young Mice · 2026 · Related
  15. Micro- and nanoplastics: A new cardiovascular risk factor? · Xiaoqi Zhu · 2022 · 264 citations · Cited by this paper
  16. Microplastics and Nanoplastics in Cardiovascular Disease: An Emerging Cardiovascular Risk Factor · 2026 · Related
  17. Microplastics: Human exposure assessment through air, water, and food · Giuseppina Zuri · 2023 · 232 citations · Cited by this paper
  18. Microplastics and Cardiovascular Disease: Should Clinicians Be Paying Attention? · 2025 · Related
  19. Detection of microplastics in human saphenous vein tissue using μFTIR: A pilot study · Jeanette M. Rotchell · 2023 · 165 citations · Cited by this paper
  20. Assessing the Efficacy of Pyrolysis–Gas Chromatography–Mass Spectrometry for Nanoplastic and Microplastic Analysis in Human Blood · Cassandra Rauert · 2025 · 155 citations · Cited by this paper
  21. Systematic review of microplastics and nanoplastics in indoor and outdoor air: identifying a framework and data needs for quantifying human inhalation exposures · Tiffany Eberhard · 2024 · 143 citations · Cited by this paper
  22. Low-dose of polystyrene microplastics induce cardiotoxicity in mice and human-originated cardiac organoids · Yue Zhou · 2023 · 134 citations · Cited by this paper
  23. Patterns of microparticles in blank samples: A study to inform best practices for microplastic analysis · Keenan Munno · 2023 · 121 citations · Cited by this paper
  24. Polystyrene bead ingestion promotes adiposity and cardiometabolic disease in mice · Jingjing Zhao · 2022 · 116 citations · Cited by this paper
  25. Polystyrene nanoparticles affecting blood coagulation · Cecilia Oslakovic · 2011 · 111 citations · Cited by this paper
  26. Microplastics are associated with elevated atherosclerotic risk and increased vascular complexity in acute coronary syndrome patients · Yunxiao Yang · 2024 · 91 citations · Cited by this paper
  27. Amine-modified nanoplastics promote the procoagulant activation of isolated human red blood cells and thrombus formation in rats · Eun-Hye Kim · 2022 · 66 citations · Cited by this paper
  28. Microplastics analytics: why we should not underestimate the importance of blank controls · Michael James Noonan · 2023 · 64 citations · Cited by this paper
  29. Induction and enhancement of platelet aggregation in vitro and in vivo by model polystyrene nanoparticles · Erica Smyth · 2014 · 62 citations · Cited by this paper
  30. Microplastics and nanoplastics in cardiovascular disease—a narrative review with worrying links · Haixiang Zheng · 2024 · 57 citations · Cited by this paper
  31. SGLT2 inhibition ameliorates nano plastics-induced premature endothelial senescence and dysfunction · Bikalpa Dhakal · 2023 · 48 citations · Cited by this paper
  32. Multi-dimensional evaluation of cardiotoxicity in mice following respiratory exposure to polystyrene nanoplastics · Tianyi Zhang · 2023 · 47 citations · Cited by this paper
  33. Potential Effects of Orally Ingesting Polyethylene Terephthalate Microplastics on the Mouse Heart · Tao Lu · 2024 · 34 citations · Cited by this paper
  34. Microplastics and nanoplastics: emerging threats to cardiovascular health – a comprehensive review · Hamza Irfan · 2024 · 32 citations · Cited by this paper
  35. Dysfunctional high-density lipoprotein: an updated review · Frances W. Ouyang · 2025 · 32 citations · Cited by this paper
  36. Morphological and lipid metabolism alterations in macrophages exposed to model environmental nanoplastics traced by high-resolution synchrotron techniques · Federica Zingaro · 2023 · 31 citations · Cited by this paper
  37. Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review · Adrian Goldsworthy · 2025 · 30 citations · Cited by this paper
  38. Health Risks from Microplastics in Intravenous Infusions: Evidence from Italy, Spain, and Ecuador · Claudio Casella · 2025 · 29 citations · Cited by this paper
  39. Microplastic and nanoplastic pollution and associated potential disease risks · Nurshad Ali · 2025 · 27 citations · Cited by this paper

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