Research map: Updating Aggregate Consumer Exposure Assessment for Cosmetics and Personal Care Products: Phase IV of the Creme RIFM Aggregate Exposure Model Back to the article
Papers in this map Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products · Bob J. Safford · 2015 · 1928 citations · Cited by this paperUpdates to the RIFM Criteria Document for fragrance ingredient evaluation · A.M. Api · 2026 · 1 citation · Cites this paperComprehensive analysis of the association between perfluorooctanoic acid exposure and osteosarcoma progression · 2026 · RelatedNovel database for exposure to fragrance ingredients in cosmetics and personal care products · Damien Comiskey · 2015 · 1870 citations · Cited by this paperStrategic application of New Approach Methodologies (NAMs) in fragrance ingredient safety assessment: Integration of in vitro, in silico, and exposure-based approaches in RIFM evaluations · Isabelle Lee · 2026 · Cites this paperThe tire antioxidant derivative 6PPD-quinone exacerbates IBD by targeting NR1H4-mediated lipid metabolism and mitochondrial dysfunction in human colon epithelial cells · 2026 · RelatedApplication of the expanded Creme RIFM consumer exposure model to fragrance ingredients in cosmetic, personal care and air care products · Bob J. Safford · 2017 · 1851 citations · Cited by this paperAlternariol, a mycotoxin, induces oxidative stress, inflammation, and apoptosis in human astrocytes: Protective effects of eicosapentaenoic acid · 2026 · RelatedIntegrating habits and practices data for soaps, cosmetics and air care products into an existing aggregate exposure model · Damien Comiskey · 2017 · 1826 citations · Cited by this paperIntegrative network toxicology identifies SLC5A2 as a key mediator of tetrasodium pyrophosphate-induced renal fibrosis · 2026 · RelatedUsage patterns of personal care products: Important factors for exposure assessment · Jacqueline W.H. Biesterbos · 2012 · 217 citations · Cited by this paperRIFM fragrance ingredient safety assessment, 3,5,5-trimethylcyclohexanol, CAS Registry Number 116-02-9 · 2026 · RelatedExposure data for cosmetic products: lipstick, body lotion, and face cream · Linda Loretz · 2004 · 191 citations · Cited by this paperBPAF-induced inflammatory response via estrogen signaling: insights from in vivo and in vitro evidence · 2026 · RelatedEuropean consumer exposure to cosmetic products, a framework for conducting population exposure assessments · Barbara M. Hall · 2007 · 162 citations · Cited by this paperUpdate to RIFM fragrance ingredient safety assessment, 2-propanol, 1,1′,1′,1'-(1,2-ethanediyldinitrilo)tetrakis-, CAS Registry Number 102-60-3 · 2026 · RelatedExposure data for cosmetic products: Facial cleanser, hair conditioner, and eye shadow · Linda Loretz · 2007 · 149 citations · Cited by this paperRedox-dependent cytoprotection by zerumbone via Nrf2–Keap1 mediated restoration of antioxidant and apoptotic balance in Mancozeb-exposed cells · 2026 · RelatedCorrigendum to “Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products” [Regul. Toxicol. Pharmacol. 72 3 (2015) 673-68] · Bob J. Safford · 2024 · 111 citations · Cited by this paperMicroplastics and mammary carcinogenesis: A review of in vitro and in vivo experimental evidence · 2026 · RelatedProbabilistic assessment of exposure to cosmetic products by French children aged 0–3 years · A.S. Ficheux · 2016 · 22 citations · Cited by this paperDetailed aggregate exposure analysis shows that exposure to fragrance ingredients in consumer products is low: Many orders of magnitude below thresholds of concern · Isabelle Lee · 2024 · 7 citations · Cited by this paperIncorporating Singaporean habits and practices for cosmetics and personal care products into a global consumer aggregate exposure model · Siti Amelia Juraimi · 2024 · 7 citations · Cited by this paperIntegrating new habits and practices data and homecare products into the Creme RIFM aggregate exposure model · Isabelle Lee · 2026 · 2 citations · Cited by this paperSource: OpenAlex (CC0)