Research map: Long-term Effects of Gamma-aminobutyric Acid on Lipid Metabolism, Inflammatory Responses, and Insulin Sensitivity in 3T3-L1 Adipocytes

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  1. The Epidemiology of Obesity: A Big Picture · Adela Hruby · 2014 · 3014 citations · Cited by this paper
  2. Investigation of the in vivo antidiabetic effects of vildagliptin–fenugreek loaded liposomes by preventing GLP-1 and GIP degradation · 2026 · Related
  3. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance · Philip A. Kern · 2001 · 1897 citations · Cited by this paper
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  9. Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects · Victoria Rotter · 2003 · 1058 citations · Cited by this paper
  10. BL-918 as a Novel Neuroprotective Agent Targeting SMP30 in Parkinson’s Disease: A Therapeutic Evaluation · 2026 · Related
  11. Interleukin-6 Induces Cellular Insulin Resistance in Hepatocytes · Joseph J. Senn · 2002 · 889 citations · Cited by this paper
  12. Phytochemical profiling and anti-inflammatory activity of Citrus hystrix DC. Peel essential oil · 2026 · Related
  13. TNF‐α and adipocyte biology · William Peter Cawthorn · 2007 · 800 citations · Cited by this paper
  14. In silico Screening of Phytochemicals from Kaidaryadi Kashayam for Multitarget Modulation of Helicobacter pylori Pathogenesis · 2026 · Related
  15. Inhibitory role for GABA in autoimmune inflammation · R. Bhat · 2010 · 518 citations · Cited by this paper
  16. Neuroprotective effects of Moringa oleifera, Mucuna pruriens, and Silybum marianum in a rotenone-induced Parkinson’s disease model · 2026 · Related
  17. Chronic Exposure to Interleukin-6 Causes Hepatic Insulin Resistance in Mice · Peter J. Klover · 2003 · 488 citations · Cited by this paper
  18. Potential Renoprotective Effects of Physalis angulata L. Active Fraction on Podocytopathy, Inflammation, Tubular Injury, and Fibrosis in a Diabetic Nephropathy Rat Model · 2026 · Related
  19. The role of infiltrating immune cells in dysfunctional adipose tissue · Tomasz Jan Guzik · 2017 · 456 citations · Cited by this paper
  20. Protective effects of Pluchea indica aqueous leaves tea extract against oxidative stress and inflammation in a dextran sulfate sodium-induced colitis rat model · 2026 · Related
  21. Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone · Claire Lagathu · 2003 · 382 citations · Cited by this paper
  22. The role of adipokines in chronic inflammation · Peter Mancuso · 2016 · 379 citations · Cited by this paper
  23. GABA and GABA receptors in the gastrointestinal tract: from motility to inflammation · Michelangelo Auteri · 2014 · 313 citations · Cited by this paper
  24. A study on relationship between elderly sarcopenia and inflammatory factors IL-6 and TNF-α · Ai-Lin Bian · 2017 · 305 citations · Cited by this paper
  25. Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation · Sardar T. A. K. Sindhu · 2015 · 273 citations · Cited by this paper
  26. Oral Treatment with γ-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice · Jide Tian · 2011 · 200 citations · Cited by this paper
  27. GABAA receptors mediate inhibition of T cell responses · Jide Tian · 1999 · 166 citations · Cited by this paper
  28. The peripheral GABAergic system as a target in endocrine disorders · Anatoliy V. Gladkevich · 2005 · 135 citations · Cited by this paper
  29. GABA (A) receptor subunits RNA expression in mice peritoneal macrophages modulate their IL-6/IL-12 production · María Guadalupe Reyes-García · 2007 · 124 citations · Cited by this paper
  30. γ-Aminobutyric acid found in fermented foods and beverages: current trends · Novia Rahmah Maulani Sahab · 2020 · 114 citations · Cited by this paper
  31. GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity · Injae Hwang · 2019 · 94 citations · Cited by this paper
  32. Anti-Obesity Effects of Germinated Brown Rice Extract through Down-Regulation of Lipogenic Genes in High Fat Diet-Induced Obese Mice · Jin‐Nyoung Ho · 2012 · 63 citations · Cited by this paper
  33. GABAA receptors in the lateral hypothalamus as mediators of satiety and body weight regulation · Christine I. Turenius · 2009 · 59 citations · Cited by this paper
  34. Gamma-aminobutyric acid attenuates insulin resistance in type 2 diabetic patients and reduces the risk of insulin resistance in their offspring · Hossein Rezazadeh · 2021 · 40 citations · Cited by this paper
  35. Anti-Obesity Effects of GABA in C57BL/6J Mice with High-Fat Diet-Induced Obesity and 3T3-L1 Adipocytes · Heegu Jin · 2024 · 29 citations · Cited by this paper
  36. The components required for amino acid neurotransmitter signaling are present in adipose tissues · Anne Nicolaysen · 2007 · 24 citations · Cited by this paper
  37. GABA Prevents Age-Related Sarcopenic Obesity in Mice with High-Fat-Diet-Induced Obesity · Heegu Jin · 2023 · 23 citations · Cited by this paper
  38. Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo · Ping Yang · 2015 · 22 citations · Cited by this paper
  39. Positive Regulation by GABABR1 Subunit of Leptin Expression through Gene Transactivation in Adipocytes · Yukari Nakamura · 2011 · 18 citations · Cited by this paper

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