Research map: Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation

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  24. Leukotrienes augment interleukin 1 production by human monocytes. · Marek Rola‐Pleszczynski · 1985 · 249 citations · Cited by this paper
  25. What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases · Joseph L. Evans · 2008 · 234 citations · Cited by this paper
  26. Leukotriene B4: Metabolism and Signal Transduction · Takehiko Yokomizo · 2001 · 233 citations · Cited by this paper
  27. 5-Lipoxygenase and FLAP · Marc L. Peters-Golden · 2003 · 199 citations · Cited by this paper
  28. Oral Leukotriene Inhibitor (MK-886) Blocks Allergen-induced Airway Responses · Beth S. Friedman · 1993 · 162 citations · Cited by this paper
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  31. The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo · Zuzana Diamant · 1995 · 158 citations · Cited by this paper
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  33. Microarray analysis of gene expression in multiple sclerosis and EAE identifies 5-lipoxygenase as a component of inflammatory lesions · Laurie Ward Whitney · 2001 · 150 citations · Cited by this paper
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  35. The acute inflammatory process, arachidonic acid metabolism and the mode of action of anti‐inflammatory drugs · A.J. Higgins · 1984 · 146 citations · Cited by this paper
  36. Leukotriene B4 enhances the activity of nuclear factor- B pathway through BLT1 and BLT2 receptors in atherosclerosis · Eva Sánchez-Galán · 2008 · 145 citations · Cited by this paper
  37. Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression · C. Henrique Serezani · 2011 · 144 citations · Cited by this paper
  38. Leukotriene B4Strongly Increases Monocyte Chemoattractant Protein-1 in Human Monocytes · Li Huang · 2004 · 143 citations · Cited by this paper
  39. Leukotriene B4 enhances interleukin-6 (IL-6) production and IL-6 messenger RNA accumulation in human monocytes in vitro: transcriptional and posttranscriptional mechanisms · Marek Rola‐Pleszczynski · 1992 · 131 citations · Cited by this paper

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