Research map: Deciphering the colorectal tumor microenvironment: Interactions and targets for effective therapy

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  1. The consensus molecular subtypes of colorectal cancer · Justin Guinney · 2015 · 5424 citations · Cited by this paper
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  19. Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer · Marie Tosolini · 2011 · 1150 citations · Cited by this paper
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  24. Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers · Takuro Saito · 2016 · 910 citations · Cited by this paper
  25. CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer · Jinwei Hu · 2019 · 829 citations · Cited by this paper
  26. Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer · Senlin Zhao · 2020 · 825 citations · Cited by this paper
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  31. Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer · Weihao Li · 2023 · 457 citations · Cited by this paper
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  35. Tumor-Associated Macrophages (TAMs) in Colorectal Cancer (CRC): From Mechanism to Therapy and Prognosis · Hui Wang · 2021 · 367 citations · Cited by this paper
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  38. STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis · Christina Heichler · 2019 · 339 citations · Cited by this paper
  39. IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation · Yijing Li · 2012 · 331 citations · Cited by this paper

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