Research map: Clinical utility and cost-effectiveness of universal tumor screening to identify Lynch syndrome in patients with stage II/III colorectal cancer: a prospective observational study in Japan

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  1. Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability · Asad Umar · 2004 · 3221 citations · Cited by this paper
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  11. Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives · 2009 · 690 citations · Cited by this paper
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  15. Identification of Lynch Syndrome Among Patients With Colorectal Cancer · Leticia Moreira · 2012 · 571 citations · Cited by this paper
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  17. Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer · Francis M. Giardiello · 2014 · 568 citations · Cited by this paper
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  19. Population-Based Molecular Detection of Hereditary Nonpolyposis Colorectal Cancer · Reijo Salovaara · 2000 · 524 citations · Cited by this paper
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  21. Identification and Survival of Carriers of Mutations in DNA Mismatch-Repair Genes in Colon Cancer · Rebecca A. Barnetson · 2006 · 479 citations · Cited by this paper
  22. EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome · Glenn E. Palomaki · 2009 · 471 citations · Cited by this paper
  23. Adjuvant Therapy for Stage II Colon Cancer: ASCO Guideline Update · Nancy Noel Baxter · 2021 · 365 citations · Cited by this paper
  24. Strategies to Identify the Lynch Syndrome Among Patients With Colorectal Cancer · Uri Ladabaum · 2011 · 342 citations · Cited by this paper
  25. Microsatellite Instability in Patients With Stage III Colon Cancer Receiving Fluoropyrimidine With or Without Oxaliplatin: An ACCENT Pooled Analysis of 12 Adjuvant Trials · Romain Cohen · 2020 · 180 citations · Cited by this paper
  26. Familial risk-colorectal cancer: ESMO Clinical Practice Guidelines · Judith Balmañà · 2013 · 167 citations · Cited by this paper
  27. Uptake of Genetic Testing by Relatives of Lynch Syndrome Probands: A Systematic Review · Ravi N. Sharaf · 2013 · 146 citations · Cited by this paper
  28. Worldwide prevalence of Lynch syndrome in patients with colorectal cancer: Systematic review and meta-analysis · Nadine Abu‐Ghazaleh · 2022 · 99 citations · Cited by this paper
  29. Methylation Analysis of MLH1 Improves the Selection of Patients for Genetic Testing in Lynch Syndrome · Lucía Pérez–Carbonell · 2010 · 82 citations · Cited by this paper
  30. A tailored approach to BRAF and MLH1 methylation testing in a universal screening program for Lynch syndrome · Tomer Adar · 2017 · 76 citations · Cited by this paper
  31. Which Lynch syndrome screening programs could be implemented in the “real world”? A systematic review of economic evaluations · Marco Di Marco · 2018 · 70 citations · Cited by this paper
  32. Prevalence of Lynch syndrome and Lynch-like syndrome among patients with colorectal cancer in a Japanese hospital-based population · Noriyasu Chika · 2016 · 62 citations · Cited by this paper
  33. Universal screening for Lynch syndrome in a large consecutive cohort of Chinese colorectal cancer patients: High prevalence and unique molecular features · Jiang Wu · 2018 · 55 citations · Cited by this paper
  34. Population-based Screening for Hereditary Colorectal Cancer Variants in Japan · Masashi Fujita · 2020 · 51 citations · Cited by this paper
  35. Lynch syndrome–associated colorectal carcinoma: frequent involvement of the left colon and rectum and late-onset presentation supports a universal screening approach · Douglas J. Hartman · 2013 · 30 citations · Cited by this paper
  36. Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population · Dayna R. Cenin · 2018 · 18 citations · Cited by this paper
  37. Comparison of universal screening in major lynch-associated tumors: a systematic review of literature · George Kunnackal John · 2021 · 11 citations · Cited by this paper
  38. Worldwide variation in lynch syndrome screening: case for universal screening in low colorectal cancer prevalence areas · George Kunnackal John · 2020 · 10 citations · Cited by this paper
  39. Japanese society for cancer of the colon and rectum (JSCCR) guidelines 2024 for the clinical practice of hereditary colorectal cancer · Kohji Tanakaya · 2025 · 6 citations · Cited by this paper

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