Research map: Continuous apomorphine infusion modulates cortical hyperexcitability and abnormal plasticity in Parkinson's disease

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Papers in this map

  1. MDS clinical diagnostic criteria for Parkinson's disease · Ronald B. Postuma · 2015 · 7781 citations · Cited by this paper
  2. Integrating a biopsychosocial perspective: WHODAS 2.0 enhances functioning assessment in Parkinson's disease · 2026 · Related
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  11. Apomorphine subcutaneous infusion in patients with Parkinson's disease with persistent motor fluctuations (TOLEDO): a multicentre, double-blind, randomised, placebo-controlled trial · Regina Katzenschlager · 2018 · 338 citations · Cited by this paper
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  13. Motor cortex plasticity in Parkinson's disease and levodopa-induced dyskinesias · Francesca Morgante · 2006 · 326 citations · Cited by this paper
  14. Rethinking the concept of disease modification in an evolving Parkinson's disease treatment landscape · 2026 · Related
  15. Abnormal facilitation of the response to transcranial magnetic stimulation in patients with Parkinson's disease · Josep Valls‐Solé · 1994 · 237 citations · Cited by this paper
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  17. Apomorphine for Parkinson’s Disease: Efficacy and Safety of Current and New Formulations · Federico Carbone · 2019 · 190 citations · Cited by this paper
  18. Gut microbiome dysbiosis, short-chain fatty acid depletion and implications for neuroinflammation in atypical parkinsonian syndromes – a systematic review of patient cohorts · 2026 · Related
  19. European Academy of Neurology/Movement Disorder Society‐European Section Guideline on the Treatment of Parkinson's Disease: I. Invasive Therapies · Günther Deuschl · 2022 · 190 citations · Cited by this paper
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  21. Dosage-dependent non-linear effect of l -dopa on human motor cortex plasticity · Katia Karina Monte-Silva · 2010 · 176 citations · Cited by this paper
  22. Increased motor cortical facilitation and decreased inhibition in Parkinson disease · Zhen Ni · 2013 · 150 citations · Cited by this paper
  23. Neurophysiological correlates of bradykinesia in Parkinson’s disease · Matteo Bologna · 2018 · 148 citations · Cited by this paper
  24. Consensus paper on short-interval intracortical inhibition and other transcranial magnetic stimulation intracortical paradigms in movement disorders · Alfredo Berardelli · 2008 · 140 citations · Cited by this paper
  25. Functional reorganization of sensorimotor cortex in early Parkinson disease · Maja Kojović · 2012 · 132 citations · Cited by this paper
  26. Effects of chronic levodopa and pergolide treatment on cortical excitability in patients with Parkinson's disease: a transcranial magnetic stimulation study · Antonio P. Strafella · 2000 · 129 citations · Cited by this paper
  27. Abnormal bidirectional plasticity-like effects in Parkinson's disease · Ying‐Zu Huang · 2011 · 125 citations · Cited by this paper
  28. Lack of LTP-like plasticity in primary motor cortex in Parkinson's disease · Antonio Suppa · 2010 · 119 citations · Cited by this paper
  29. Early, severe and bilateral loss of LTP and LTD-like plasticity in motor cortex (M1) in de novo Parkinson’s disease · Asha Kishore · 2011 · 116 citations · Cited by this paper
  30. Clinical neurophysiology of Parkinson’s disease and parkinsonism · Robert E. Chen · 2022 · 105 citations · Cited by this paper
  31. Long-term safety and efficacy of apomorphine infusion in Parkinson's disease patients with persistent motor fluctuations: Results of the open-label phase of the TOLEDO study · Regina Katzenschlager · 2021 · 88 citations · Cited by this paper
  32. Subcutaneous continuous apomorphine infusion in fluctuating patients with Parkinson's disease: long-term results · Fabrizio Stocchi · 2001 · 87 citations · Cited by this paper
  33. Cortical disinhibition in Parkinson’s disease · Claudia Ammann · 2020 · 86 citations · Cited by this paper
  34. Continuous subcutaneous apomorphine infusion in advanced Parkinson’s disease: 10-year experience with 230 patients · Ángel Sesar · 2017 · 85 citations · Cited by this paper
  35. Acute dopamine boost has a negative effect on plasticity of the primary motor cortex in advanced Parkinson's disease · Asha Kishore · 2012 · 84 citations · Cited by this paper
  36. Transcranial magnetic stimulation follow‐up study in early Parkinson's disease: A decline in compensation with disease progression? · Maja Kojović · 2015 · 78 citations · Cited by this paper
  37. Abnormal cortical facilitation and L-dopa-induced dyskinesia in Parkinson's disease · Andrea Guerra · 2019 · 69 citations · Cited by this paper
  38. Theta burst stimulation over the primary motor cortex does not induce cortical plasticity in Parkinson’s disease · Carsten Eggers · 2010 · 63 citations · Cited by this paper
  39. Continuous subcutaneous apomorphine infusion in Parkinson's disease patients with cognitive dysfunction: A retrospective long-term follow-up study · Robbert W. K. Borgemeester · 2017 · 53 citations · Cited by this paper

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