Research map: EGFR inhibition promotes functional engraftment and graft survival via donor-derived CHI3L1 in fetal RPE suspension transplantation

Back to the article

Papers in this map

  1. Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration · Michiko Mandai · 2017 · 1563 citations · Cited by this paper
  2. Leave No Data Behind: Exploring a new paradigm in oncology with foundation models and large language models · 2026 · Related
  3. Embryonic stem cell trials for macular degeneration: a preliminary report · Steven D. Schwartz · 2012 · 1423 citations · Cited by this paper
  4. Self-sufficient killing of malignant tumors by an engineered cancer-selective gene circuit · 2026 · Related
  5. Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies · Steven D. Schwartz · 2014 · 1349 citations · Cited by this paper
  6. Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID · 2026 · Related
  7. Chitinase-3 like-protein-1 function and its role in diseases · Ting Zhao · 2020 · 582 citations · Cited by this paper
  8. Repurposed ethoxzolamide reprograms antitumor immunity through β-TrCP-dependent PD-L1 ubiquitination · 2026 · Related
  9. Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing · Donald Richieri Griffin · 2020 · 510 citations · Cited by this paper
  10. Combine antibody-drug conjugate with cmLumiOpto for triple-negative breast cancer treatment · 2026 · Related
  11. Distinct contributions of partial and full EMT to breast cancer malignancy · Fabiana Lüönd · 2021 · 412 citations · Cited by this paper
  12. Case of complete response to immunotherapy in MMR-deficient prostate cancer associated with NK-like and CD4+CD8+ T cells · 2026 · Related
  13. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration · Amir H. Kashani · 2018 · 396 citations · Cited by this paper
  14. Therapeutic Gfral silencing via antisense oligonucleotides ameliorates cancer-associated cachexia and extends survival in tumor-bearing mice · 2026 · Related
  15. Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs · Ruchi Sharma · 2019 · 375 citations · Cited by this paper
  16. Köhlmeier-Degos disease is an interferonopathy characterized by type I and II interferon-driven inflammatory vasculopathy · 2026 · Related
  17. Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation · Simon McArthur · 2020 · 204 citations · Cited by this paper
  18. Metabolomic and lifestyle profiles refine BMI-metabolic phenotypes in older adults · 2026 · Related
  19. The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer · Tarek Taifour · 2023 · 201 citations · Cited by this paper
  20. Alterations of the host-lung microbiome metasystem in systemic inflammatory response syndrome is associated with secondary pneumonia · 2026 · Related
  21. HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration · Sunao Sugita · 2020 · 193 citations · Cited by this paper
  22. CHI3L1 regulates PD-L1 and anti–CHI3L1–PD-1 antibody elicits synergistic antitumor responses · Bing Ma · 2021 · 112 citations · Cited by this paper
  23. Regenerative and restorative medicine for eye disease · Russell Neil Van Gelder · 2022 · 110 citations · Cited by this paper
  24. Immunosuppression via Loss of IL2rγ Enhances Long-Term Functional Integration of hESC-Derived Photoreceptors in the Mouse Retina · Jie Zhu · 2017 · 90 citations · Cited by this paper
  25. Immunological aspects of RPE cell transplantation · Sunao Sugita · 2021 · 78 citations · Cited by this paper
  26. Allogeneic iPSC-Derived RPE Cell Graft Failure Following Transplantation Into the Subretinal Space in Nonhuman Primates · Trevor J. McGill · 2018 · 76 citations · Cited by this paper
  27. Immunohistochemical Toolkit for Tracking and Quantifying Xenotransplanted Human Stem Cells · Justine Allard · 2014 · 65 citations · Cited by this paper
  28. A role for partial epithelial-to-mesenchymal transition in enabling stemness in homeostasis and cancer · Jeroen Verstappe · 2023 · 63 citations · Cited by this paper
  29. Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2 · Yu Chen · 2024 · 63 citations · Cited by this paper
  30. Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases · Hang Liu · 2024 · 36 citations · Cited by this paper
  31. Integrin activation or alpha9 expression allows retinal pigmented epithelial cell adhesion on Bruch’s membrane in wet age-related macular degeneration · Fardad T. Afshari · 2010 · 32 citations · Cited by this paper
  32. Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats · Deepthi S. Rajendran Nair · 2021 · 29 citations · Cited by this paper
  33. A ROCK Inhibitor Promotes Graft Survival during Transplantation of iPS-Cell-Derived Retinal Cells · Masaaki Ishida · 2021 · 25 citations · Cited by this paper
  34. Identifying biomarkers of heterogeneity and transplantation efficacy in retinal pigment epithelial cells · Farhad Farjood · 2023 · 24 citations · Cited by this paper
  35. PBX/Knotted 1 homeobox-2 (PKNOX2) is a novel regulator of myocardial fibrosis · Liang Chen · 2024 · 15 citations · Cited by this paper
  36. Graft survival of major histocompatibility complex deficient stem cell-derived retinal cells · Masaaki Ishida · 2024 · 15 citations · Cited by this paper
  37. Safety and tolerability of RPESC-RPE transplantation in patients with dry age-related macular degeneration: Low-dose clinical outcomes · Rajesh C. Rao · 2025 · 15 citations · Cited by this paper
  38. Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage · Keisuke Kajita · 2024 · 11 citations · Cited by this paper
  39. A Novel Role of IL13Rα2 in the Pathogenesis of Proliferative Vitreoretinopathy · Hui Qi · 2022 · 6 citations · Cited by this paper

Source: OpenAlex (CC0)