Research map: Environmental impact of antidepressants: Is a new prescription framework possible?

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Papers in this map

  1. Pharmaceutical pollution of the world’s rivers · John L. Wilkinson · 2022 · 1644 citations · Cited by this paper
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  5. Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions · Roger S. McIntyre · 2023 · 805 citations · Cited by this paper
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  7. Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms · Robert J. DeRubeis · 2008 · 700 citations · Cited by this paper
  8. Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications · 2026 · Related
  9. Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed · Chris D. Metcalfe · 2010 · 506 citations · Cited by this paper
  10. MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx) · 2026 · Related
  11. Stahl's Essential Psychopharmacology · Stephen M. Stahl · 2021 · 478 citations · Cited by this paper
  12. Population pharmacokinetics and pharmacodynamics of canagliflozin in paediatric patients with type 2 diabetes mellitus · 2026 · Related
  13. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults: Réseau canadien pour les traitements de l'humeur et de l'anxiété (CANMAT) 2023 : Mise à jour des lignes directrices cliniques pour la prise en charge du trouble dépressif majeur chez les adultes · Raymond Wing Moon Lam · 2024 · 357 citations · Cited by this paper
  14. Trends in publicly subsidized and private access to GLP‐1 medicines indicated for type 2 diabetes in Australia, 2020–2025 · 2026 · Related
  15. CRED: Criteria for reporting and evaluating ecotoxicity data · Caroline Moermond · 2015 · 345 citations · Cited by this paper
  16. Analysis of spontaneous reports of suspected adverse reactions related to medical cannabis from the Italian Phytovigilance System · 2026 · Related
  17. The Italian health-care system · George France · 2005 · 330 citations · Cited by this paper
  18. A university‐certified course on dossier assessment for regulatory scientists in Africa—Reporting on our 5‐year experience · 2026 · Related
  19. Antibiotics and antidepressants occurrence in surface waters and sediments collected in the north of Portugal · Maria João Fernandes · 2019 · 187 citations · Cited by this paper
  20. Perceptions of prescribing violations by doctors: A qualitative study using semi‐structured interviews · 2026 · Related
  21. Antidepressant drugs as emerging contaminants: Occurrence in urban and non-urban waters and analytical methods for their detection · Carlos Castillo-Zacarías · 2020 · 187 citations · Cited by this paper
  22. Tracking the occurrence of psychotropic pharmaceuticals in Brazilian wastewater treatment plants and surface water, with assessment of environmental risks · Rhannanda Copetti Pivetta · 2020 · 168 citations · Cited by this paper
  23. Residues, bioaccumulation, and trophic transfer of pharmaceuticals and personal care products in highly urbanized rivers affected by water diversion · Haohan Yang · 2020 · 154 citations · Cited by this paper
  24. Methodological approaches for studying pharmaceuticals in the environment by comparing predicted and measured concentrations in River Po, Italy · Sara Castiglioni · 2003 · 120 citations · Cited by this paper
  25. Antidepressant Withdrawal and Rebound Phenomena · Jonathan F. Henssler · 2019 · 118 citations · Cited by this paper
  26. Association Between Depression and Physical Conditions Requiring Hospitalization · Philipp Frank · 2023 · 114 citations · Cited by this paper
  27. Strategies to reduce use of antidepressants · Tony Kendrick · 2020 · 102 citations · Cited by this paper
  28. Environmental risk assessment of three selective serotonin reuptake inhibitors in the aquatic environment: A case study including a cocktail scenario · Bjarne Styrishave · 2010 · 96 citations · Cited by this paper
  29. Environmental levels of the antidepressant venlafaxine impact the metabolic capacity of rainbow trout · Carol Best · 2014 · 75 citations · Cited by this paper
  30. Occurrence and source analysis of selected antidepressants and their metabolites in municipal wastewater and receiving surface water · Luo-dan Ma · 2018 · 73 citations · Cited by this paper
  31. Human pharmaceuticals in three major fish species from the Uruguay River (South America) with different feeding habits · Macarena Rojo · 2019 · 68 citations · Cited by this paper
  32. Chronic exposure to venlafaxine and increased water temperature reversibly alters microRNA in zebrafish gonads (Danio rerio) · Heather Ikert · 2019 · 36 citations · Cited by this paper
  33. Periphyton, bivalves and fish differentially accumulate select pharmaceuticals in effluent-dependent stream mesocosms · S. Rebekah Burket · 2020 · 28 citations · Cited by this paper
  34. Antidepressants in primary care: limited value at the first visit · Bruce Arroll · 2023 · 26 citations · Cited by this paper
  35. Sertraline inhibits top-down forces (predation) in microbial food web and promotes nitrification in sediment · Yi Li · 2020 · 24 citations · Cited by this paper
  36. Developmental exposure to sertraline impaired zebrafish behavioral and neurochemical profiles · Melissa Faria · 2022 · 23 citations · Cited by this paper
  37. Predicting Environmental Risks of Pharmaceuticals from Wholesale Data: An Example from Norway · Samuel A. Welch · 2023 · 17 citations · Cited by this paper
  38. The environmental impact of pharmaceuticals in Italy: Integrating healthcare and eco‐toxicological data to assess and potentially mitigate their diffusion to water supplies · Valentina Giunchi · 2023 · 16 citations · Cited by this paper
  39. Antidepressant sertraline impairs the induced morphological defense of Ceriodaphnia cornuta in response to Chaoborus larvae kairomone · Shuangshuang Zhu · 2020 · 14 citations · Cited by this paper

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