Research map: Mechanical loading vs. hypoxic stress: differential regulation of circulating irisin, myostatin, and HIF-1α following resistance training in young adults with overweight

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  1. Obesity in children and adolescents: epidemiology, causes, assessment, and management · Hiba Jebeile · 2022 · 994 citations · Cited by this paper
  2. Running in the heat reduces time to task failure, attenuates biomarkers of muscle microtrauma, and exacerbates low-frequency force depression and cardiac vagal withdrawal over 72-h post-exercise · Yago Medeiros Dutra · 2026 · Related
  3. Myostatin Inhibits Myoblast Differentiation by Down-regulating MyoD Expression · Brett C. Langley · 2002 · 911 citations · Cited by this paper
  4. Circadian phenotype is associated with diurnal variation in human exercise performance · 2026 · Related
  5. Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia. · Jennifer E. Ziello · 2007 · 673 citations · Cited by this paper
  6. Variable intensity interval training improves cardiorespiratory fitness and quality of life across Hashimoto’s stages and lowers TSH in subclinical patients: a 12-week supervised study · 2026 · Related
  7. Effects of Blood Flow Restriction Training on Muscular Strength and Hypertrophy in Older Individuals: A Systematic Review and Meta-Analysis · Christoph Centner · 2018 · 374 citations · Cited by this paper
  8. Endocrine and neuromodulatory regulation during prolonged maximal 6000-m rowing in male athletes · 2026 · Related
  9. Training adaptations in the behavior of human motor units · Jacques Duchateau · 2006 · 352 citations · Cited by this paper
  10. Neck cooling, with or without menthol mouth rinse, improves repeated-shuttle sprint performance and perceived thermal strain in hijab-wearing female futsal players in hot-dry indoor conditions · 2026 · Related
  11. Increased Secretion and Expression of Myostatin in Skeletal Muscle From Extremely Obese Women · Dustin S. Hittel · 2008 · 322 citations · Cited by this paper
  12. Differential temporal responses of heel strike and toe off during split-belt locomotor adaptation · 2026 · Related
  13. Physical activity in obesity and metabolic syndrome · Barbara Strasser · 2012 · 283 citations · Cited by this paper
  14. Ipsilateral and contralateral microvascular kinetics during unilateral forearm cold-water immersion: a within-subject laser Doppler flowmetry and heart rate variability study · 2026 · Related
  15. Resistance exercise induces a greater irisin response than endurance exercise · Yoshifumi Tsuchiya · 2015 · 208 citations · Cited by this paper
  16. The causal effects of immune factors on sarcopenia-related phenotypes · 2026 · Related
  17. Low-intensity resistance training with blood flow restriction improves vascular endothelial function and peripheral blood circulation in healthy elderly people · Ryosuke Shimizu · 2016 · 188 citations · Cited by this paper
  18. Reliability and validity of the respiratory threshold method · 2026 · Related
  19. Human Muscle Gene Expression following Resistance Exercise and Blood Flow Restriction · Micah John Drummond · 2008 · 187 citations · Cited by this paper
  20. Effects of Heavy Resistance Training on Myostatin mRNA and Protein Expression · Darryn S. Willoughby · 2004 · 139 citations · Cited by this paper
  21. Myostatin in the Pathophysiology of Skeletal Muscle · Anne Bonnieu · 2007 · 105 citations · Cited by this paper
  22. Is irisin the new player in exercise-induced adaptations or not? A 2017 update · Ioannis G. Fatouros · 2017 · 94 citations · Cited by this paper
  23. Blood flow restriction: An evidence based progressive model (Review) · Jeremy P. Loenneke · 2012 · 92 citations · Cited by this paper
  24. Muscle mass and plasma myostatin after exercise training: a substudy of Renal Exercise (RENEXC)—a randomized controlled trial · Yunan Zhou · 2019 · 70 citations · Cited by this paper
  25. Effects of physical exercise on Irisin and BDNF concentrations, and their relationship with cardiometabolic and mental health of individuals with Metabolic Syndrome: A Systematic Review · Villamil-Parra Wilder · 2024 · 45 citations · Cited by this paper
  26. The Physiological Role of Irisin in the Regulation of Muscle Glucose Homeostasis · Naohiro Yano · 2021 · 41 citations · Cited by this paper
  27. Neuromuscular adaptations after 12 weeks of light‐ vs. heavy‐load power‐oriented resistance training in older adults · Carlos Rodríguez-López · 2021 · 40 citations · Cited by this paper
  28. Serum irisin and myostatin levels after 2 weeks of high-altitude climbing · Ewa Śliwicka · 2017 · 37 citations · Cited by this paper
  29. Effectiveness of low-load resistance training with blood flow restriction vs. conventional high-intensity resistance training in older people diagnosed with sarcopenia: a randomized controlled trial · Mei Zhang · 2024 · 32 citations · Cited by this paper
  30. The association of circulating irisin with metabolic risk factors in Chinese adults: a cross-sectional community-based study · Lizhi Tang · 2019 · 28 citations · Cited by this paper
  31. Exercise as a Therapeutic Strategy for Obesity: Central and Peripheral Mechanisms · Yiyin Zhang · 2024 · 27 citations · Cited by this paper
  32. A Review of Resistance Exercise Training in Obese Adolescents · Angela S. Alberga · 2011 · 25 citations · Cited by this paper
  33. Long- and Short-Term High-Intensity Interval Training on Lipid Profile and Cardiovascular Disorders in Obese Male Adolescents · Ghazi Racil · 2023 · 20 citations · Cited by this paper
  34. Low-Load Resistance Exercise with Blood Flow Restriction Increases Hypoxia-Induced Angiogenic Genes Expression · Rodrigo Volga Fernandes · 2022 · 17 citations · Cited by this paper
  35. Blood flow restriction combined with resistance training on muscle strength and thickness improvement in young adults: a systematic review, meta-analysis, and meta-regression · Feier Ma · 2024 · 17 citations · Cited by this paper
  36. Effects of blood flow restriction training on muscle fitness and cardiovascular risk of obese college students · Yan-Hong Su · 2024 · 14 citations · Cited by this paper
  37. HIF-1α Negatively Regulates Irisin Expression Which Involves in Muscle Atrophy Induced by Hypoxia · Shiqiang Liu · 2022 · 12 citations · Cited by this paper
  38. Vascular function responses to resistance exercise followed by intermittent hypoxic exposure in untrained males · Witid Mitranun · 2025 · 3 citations · Cited by this paper
  39. Differential Effect of Acute and Chronic Exercise on Cardiac Angiogenesis Regulator: The Role of mRNA HIF‐1 α and Its Negative Regulators of In Vivo Study · Putri Karisa · 2025 · 1 citation · Cited by this paper

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