Research map: Gb3 synthase accelerates bone wound healing by promoting the proliferation and migration of osteoblasts

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Papers in this map

  1. TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation · Yi Tang · 2009 · 1172 citations · Cited by this paper
  2. Impaired PD-1 expression in tumor-infiltrating senescent CD8+ T cells is reversed by PD-L1 blockade in a murine squamous cell carcinoma model · 2026 · Related
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  9. siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown · Pratik S. Randeria · 2015 · 224 citations · Cited by this paper
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  13. Cell adhesion, spreading, and motility of GM3-expressing cells based on glycolipid-glycolipid interaction. · Nobuhiko Kojima · 1991 · 195 citations · Cited by this paper
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  15. Targeted Disruption of Gb3/CD77 Synthase Gene Resulted in the Complete Deletion of Globo-series Glycosphingolipids and Loss of Sensitivity to Verotoxins · T. OKUDA · 2006 · 189 citations · Cited by this paper
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  17. Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration · Bo Gao · 2019 · 189 citations · Cited by this paper
  18. Orthodontic force induces local bone resorption in mild-type hypophosphatasia mouse model · 2026 · Related
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  21. Differential regulation of platelet‐derived growth factor stimulated migration and proliferation in osteoblastic cells · Meenal Mehrotra · 2004 · 72 citations · Cited by this paper
  22. Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood · Yiming Liam Liu · 2024 · 63 citations · Cited by this paper
  23. TLR4–MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide · Yuji Kondo · 2013 · 62 citations · Cited by this paper
  24. Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease · Adel Ersek · 2015 · 56 citations · Cited by this paper
  25. Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor–Rac1 Activation to Inhibit Keratinocyte Motility · Duncan Hieu M. Dam · 2016 · 51 citations · Cited by this paper
  26. Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors · Sunmi Kim · 2008 · 47 citations · Cited by this paper
  27. Gangliosides as a potential new class of stem cell markers: the case of GD1a in human bone marrow mesenchymal stem cells · Sonia Bergante · 2014 · 40 citations · Cited by this paper
  28. Inhibition of ganglioside GD1a synthesis suppresses the differentiation of human mesenchymal stem cells into osteoblasts · Hyo J. Yang · 2011 · 37 citations · Cited by this paper
  29. Current Topics in Pharmacological Research on Bone Metabolism: Osteoclast Differentiation Regulated by Glycosphingolipids · Satoshi Fukumoto · 2006 · 32 citations · Cited by this paper
  30. Nck influences preosteoblastic/osteoblastic migration and bone mass · Smriti Aryal A C · 2015 · 32 citations · Cited by this paper
  31. Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibition protects against acute kidney injury · Ivan Morace · 2019 · 31 citations · Cited by this paper
  32. Deficiency of GD3 Synthase in Mice Resulting in the Attenuation of Bone Loss with Aging · Shoyoku Yo · 2019 · 23 citations · Cited by this paper
  33. Nf2-FAK signaling axis is critical for cranial bone ossification and regeneration · Junguang Liao · 2025 · 12 citations · Cited by this paper
  34. Deletion of Gb3 Synthase in Mice Resulted in the Attenuation of Bone Formation via Decrease in Osteoblasts · Kazunori Hamamura · 2019 · 10 citations · Cited by this paper
  35. Attenuation of Bone Formation through a Decrease in Osteoblasts in Mutant Mice Lacking the GM2/GD2 Synthase Gene · Eri Sasaki · 2022 · 10 citations · Cited by this paper
  36. Regulation of Glycosylation in Bone Metabolism · Kazunori Hamamura · 2024 · 10 citations · Cited by this paper
  37. Contribution of Glucosylceramide Synthase to the Proliferation of Mouse Osteoblasts · Yoshitaka Mishima · 2021 · 6 citations · Cited by this paper
  38. Globo-series Gb4 activates ERK and promotes the proliferation of osteoblasts · Hanami Kato · 2023 · 6 citations · Cited by this paper
  39. Globotriaosylceramide Gb3 Influences Wound Healing and Scar Formation by Orchestrating Fibroblast Heterogeneity · Sujie Xie · 2025 · 4 citations · Cited by this paper

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