Research map: Redox-regulated cell death in gastric cancer: Molecular insights and therapeutic opportunities
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Papers in this map
Copper induces cell death by targeting lipoylated TCA cycle proteins
· Peter Tsvetkov · 2022 · 5027 citations · Cited by this paper
Identification of mitochondria-related genes in calcific aortic valve disease by integrated analysis of single-cell and bulk transcriptomic atlases
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The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
· Celia Andrés · 2021 · 2776 citations · Cited by this paper
Dieckol suppresses lipid accumulation and promotes thermogenic markers in 3T3-L1 adipocytes via ERK/p38 MAPK signaling
· 2026 · Related
Mitochondria as multifaceted regulators of cell death
· Florian J. Bock · 2019 · 2535 citations · Cited by this paper
Exploring the effects of lifelong aerobic exercise on early skeletal muscle remodeling between 8 and 14 months in the rat
· 2026 · Related
ROS in cancer therapy: the bright side of the moon
· Bruno Perillo · 2020 · 2212 citations · Cited by this paper
Changes in circulating bile acid levels during cold exposure are associated with brown adipose tissue in humans: a secondary analysis from the ACTIBATE study
· 2026 · Related
The role of ROS in tumour development and progression
· Eric C. Cheung · 2022 · 1616 citations · Cited by this paper
Sanguinarine Inhibits Gastric Cancer Progression by Targeting the NOS2/SOD1 Axis to Promote Ferroptosis
· 2025 · Related
ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis
· Bingqing Wang · 2023 · 859 citations · Cited by this paper
Hypoxia-inducible factor-1α: Dual roles in maintaining neuronal homeostasis and neuronal degeneration via regulation of oxidative stress, mitochondrial dynamics, and bioenergetics
· 2026 · Related
Copper metabolism in cell death and autophagy
· Qian Xue · 2023 · 699 citations · Cited by this paper
Resveratrol and dexamethasone have cell-specific effects on the circadian clock but not on the rhythm of mitochondrial function in the fetal heart
· 2026 · Related
Oxidative Stress and Cancer
· James E. Klaunig · 2019 · 623 citations · Cited by this paper
TRIM38 alleviates the pathogenesis of diabetic nephropathy by suppressing NF-κB activation via inducing RIPK1 degradation
· 2026 · Related
5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition
· Chinmayee Sethy · 2021 · 552 citations · Cited by this paper
Roles of extracellular vesicles in the pathogenesis of chronic myeloid leukemia
· 2026 · Related
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway
· Cathleen Holze · 2017 · 456 citations · Cited by this paper
Cepharanthine Triggers Ferroptosis in Gastric Cancer by PINK1/FUNDC1-Mediated Mitophagy-Dependent GPX4 Degradation
· 2026 · Related
Targeting cuproplasia and cuproptosis in cancer
· Daolin Tang · 2024 · 440 citations · Cited by this paper
Unveiling the mechanisms and challenges of cancer drug resistance
· Sameer Ullah Khan · 2024 · 400 citations · Cited by this paper
Gastric cancer
· Raghav Sundar · 2025 · 377 citations · Cited by this paper
Diversity and complexity of cell death: a historical review
· Wonyoung Park · 2023 · 344 citations · Cited by this paper
Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer
· Chenglong Sun · 2023 · 342 citations · Cited by this paper
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1
· Dongbao Li · 2022 · 337 citations · Cited by this paper
Helicobacter pylori and gastric cancer: mechanisms and new perspectives
· Yantao Duan · 2025 · 288 citations · Cited by this paper
Redox signaling in the gastrointestinal tract
· Salvador Pérez · 2017 · 287 citations · Cited by this paper
Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis
· Lindsay D. Butcher · 2017 · 249 citations · Cited by this paper
Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging
· Domenico Lapenna · 2023 · 229 citations · Cited by this paper
FDX1 regulates cellular protein lipoylation through direct binding to LIAS
· Margaret B. Dreishpoon · 2023 · 224 citations · Cited by this paper
Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis, and beyond
· Chao Mao · 2024 · 207 citations · Cited by this paper
Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species
· Shun‐ichi Yamashita · 2024 · 162 citations · Cited by this paper
Potential Applications of NRF2 Modulators in Cancer Therapy
· Emiliano Panieri · 2020 · 160 citations · Cited by this paper
Apatinib induced ferroptosis by lipid peroxidation in gastric cancer
· Liying Zhao · 2021 · 147 citations · Cited by this paper
Understanding the cell survival mechanism of anoikis-resistant cancer cells during different steps of metastasis
· Sameer Ullah Khan · 2022 · 143 citations · Cited by this paper
Redox biology and gastric carcinogenesis: the role of Helicobacter pylori
· Osamu Handa · 2011 · 128 citations · Cited by this paper
Mitochondria Related Cell Death Modalities and Disease
· Chuwen Tian · 2022 · 119 citations · Cited by this paper
RETRACTED: Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells
· Xi Chen · 2018 · 106 citations · Cited by this paper
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