Research map: Fatty acid amide metabolism in systemic lupus erythematosus: Evidence, mechanisms, and translational potential

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Papers in this map

  1. Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α · Jin Fu · 2003 · 1076 citations · Cited by this paper
  2. Decorin as a dynamic regulator in fibrosis: Mechanisms, therapeutic potential and future challenges · 2026 · Related
  3. The Nuclear Receptor Peroxisome Proliferator-Activated Receptor-α Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide · Jesse Lo Verme · 2004 · 887 citations · Cited by this paper
  4. Monocytes from patients with chronic non-bacterial osteomyelitis (CNO) exhibit increased ‘classically activated’ phenotypes and altered DNA methylation patterns · 2026 · Related
  5. STRUCTURE AND FUNCTION OF FATTY ACID AMIDE HYDROLASE · Michele K. McKinney · 2005 · 688 citations · Cited by this paper
  6. A novel JAK1 mutation identified in a patient with severe atopic dermatitis phenotype: Mechanistic insights and IL-4Rα targeted therapy · 2026 · Related
  7. Autoimmunity and organ damage in systemic lupus erythematosus · George C. Tsokos · 2020 · 609 citations · Cited by this paper
  8. The MENAT Region Inborn Errors of Immunity Research Consortium Registry (MENAT-IEI-RCR): Establishing a regional framework for collaborative research · 2026 · Related
  9. The CB2 receptor and its role as a regulator of inflammation · Caroline Turcotte · 2016 · 606 citations · Cited by this paper
  10. Metabolic syndrome and increased inflammatory burden in active rheumatoid arthritis: An exploratory focus on hematologic markers · 2026 · Related
  11. Novel paradigms in systemic lupus erythematosus · Thomas Dörner · 2019 · 581 citations · Cited by this paper
  12. Salivary polyreactive and SARS-CoV-2-specific antibody responses following SARS-CoV-2 infection and vaccination in healthcare workers · 2026 · Related
  13. Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus · Richard K. Perez · 2022 · 564 citations · Cited by this paper
  14. CLIC1 acts as a compensatory protective molecule to regulate the vascular endothelial barrier integrity in cutaneous inflammation · 2026 · Related
  15. An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee · John P. Huggins · 2012 · 377 citations · Cited by this paper
  16. Identification of a novel hypomorphic variant in CYBB underlying an adult presentation of X-linked recessive Mendelian susceptibility to mycobacterial disease · 2026 · Related
  17. Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 · Annelot C. M. van Esbroeck · 2017 · 336 citations · Cited by this paper
  18. TGF-β1/TRAF-6 and IL-6/STAT-3 pathways in PSA-PSMA phenotypes of hormone-sensitive and hormone-refractory prostate Cancer · 2026 · Related
  19. Metabolism of endocannabinoids and related N ‐acylethanolamines: Canonical and alternative pathways · Natsuo Ueda · 2013 · 243 citations · Cited by this paper
  20. Endocannabinoids and related N-acylethanolamines: biological activities and metabolism · Kazuhito Tsuboi · 2018 · 228 citations · Cited by this paper
  21. Acute Neurologic Disorder from an Inhibitor of Fatty Acid Amide Hydrolase · Anne Kerbrat · 2016 · 170 citations · Cited by this paper
  22. N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA) · Natsuo Ueda · 2010 · 166 citations · Cited by this paper
  23. Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation · Allison C. Billi · 2022 · 157 citations · Cited by this paper
  24. Biosynthesis, degradation and pharmacological importance of the fatty acid amides · Emma K. Farrell · 2008 · 126 citations · Cited by this paper
  25. Microbiome and Metabolome Analyses Reveal the Disruption of Lipid Metabolism in Systemic Lupus Erythematosus · Jingquan He · 2020 · 125 citations · Cited by this paper
  26. Microglia activation in the presence of intact blood–brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus · Dionysis Nikolopoulos · 2023 · 124 citations · Cited by this paper
  27. Endocannabinoids in immune regulation and immunopathologies · Oindrila Rahaman · 2021 · 106 citations · Cited by this paper
  28. Urine Proteomics and Renal Single‐Cell Transcriptomics Implicate Interleukin‐16 in Lupus Nephritis · Andrea Fava · 2021 · 98 citations · Cited by this paper
  29. T cells that promote B‐Cell maturation in systemic autoimmunity · Jason S. Weinstein · 2012 · 96 citations · Cited by this paper
  30. A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation · Alison Ribeiro · 2015 · 77 citations · Cited by this paper
  31. Endocannabinoid System as a Promising Therapeutic Target in Inflammatory Bowel Disease – A Systematic Review · Szymon Hryhorowicz · 2021 · 77 citations · Cited by this paper
  32. Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer · Elena Buglakova · 2024 · 74 citations · Cited by this paper
  33. Molecular Characterization of Circulating Plasma Cells in Patients with Active Systemic Lupus Erythematosus · Patricia Lugar · 2012 · 63 citations · Cited by this paper
  34. Expression and Functions of the CB2 Receptor in Human Leukocytes · Mélissa Simard · 2022 · 59 citations · Cited by this paper
  35. The essential roles of memory B cells in the pathogenesis of systemic lupus erythematosus · Thomas Dörner · 2024 · 54 citations · Cited by this paper
  36. Immunometabolism in systemic lupus erythematosus · Eduardo Patiño‐Martínez · 2025 · 53 citations · Cited by this paper
  37. Palmitoylethanolamide Modulation of Microglia Activation: Characterization of Mechanisms of Action and Implication for Its Neuroprotective Effects · Alessia D’Aloia · 2021 · 49 citations · Cited by this paper
  38. Integration of metabolomics and lipidomics reveals serum biomarkers for systemic lupus erythematosus with different organs involvement · Wenqian Zhang · 2022 · 36 citations · Cited by this paper
  39. Serum proteome and metabolome uncover novel biomarkers for the assessment of disease activity and diagnosing of systemic lupus erythematosus · Jingquan He · 2023 · 35 citations · Cited by this paper

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