Research map: Dosing challenges for chemotherapy and immunotherapy in congenital achondroplasia: a case report and literature review

Back to the article

Papers in this map

  1. Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer · Leena Gandhi · 2018 · 6765 citations · Cited by this paper
  2. Deciphering autophagy-metabolism interactions in cancer drug resistance: a comprehensive review · 2026 · Related
  3. Achondroplasia · William A. Horton · 2007 · 607 citations · Cited by this paper
  4. Pharmacokinetic and pharmacogenomic profile of capecitabine and oxaliplatin in a patient with gastric cancer undergoing hemodialysis: a case report · 2026 · Related
  5. Achondroplasia: Development, pathogenesis, and therapy · David M. Ornitz · 2016 · 274 citations · Cited by this paper
  6. Temozolomide resistance in glioma: aligning target discovery with clinically achievable CNS exposures and translational delivery strategies · 2026 · Related
  7. Evaluation of dosing strategy for pembrolizumab for oncology indications · Tomoko Freshwater · 2017 · 268 citations · Cited by this paper
  8. Physiologically based pharmacokinetic modeling of granisetron for optimizing antiemetic therapy in patients with cancer: multi-route pharmacokinetic characterization and target-site exposure prediction · 2026 · Related
  9. Fixed Dosing of Monoclonal Antibodies in Oncology · Jeroen J. M. A. Hendrikx · 2017 · 166 citations · Cited by this paper
  10. Transfer of trastuzumab and pertuzumab into human breast milk: a case report · 2026 · Related
  11. Birth prevalence of achondroplasia: A systematic literature review and meta‐analysis · Pamela K. Foreman · 2020 · 163 citations · Cited by this paper
  12. Synergistic anti-tumor activity of andrographolide and gemcitabine in intrahepatic cholangiocarcinoma through inhibition of RRM2 and the JAK/STAT3 pathway · 2026 · Related
  13. Body surface area formulae: an alarming ambiguity · Grzegorz Redlarski · 2016 · 162 citations · Cited by this paper
  14. Zolbetuximab-induced gastric mucosal injury and hypoalbuminemia: a mechanism-informed clinical analysis · 2026 · Related
  15. Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update · Jennifer J. Griggs · 2021 · 133 citations · Cited by this paper
  16. Pharmacologic de-escalation of dexamethasone during weekly paclitaxel: a randomized phase III trial evaluating safety, endocrine effects, and quality of life · 2026 · Related
  17. Assessment of kidney function: clinical indications for measured GFR · Natalie Ebert · 2021 · 125 citations · Cited by this paper
  18. Antibody–drug conjugates in colorectal cancer: molecular design, preclinical advances, and translational challenges · 2026 · Related
  19. Cancer Chemotherapy: The Case for Therapeutic Drug Monitoring · Claire E. Knezevic · 2019 · 111 citations · Cited by this paper
  20. How unmeasured muscle mass affects estimated GFR and diagnostic inaccuracy · Brian J. Nankivell · 2020 · 99 citations · Cited by this paper
  21. Alternative dosing strategies for immune checkpoint inhibitors to improve cost-effectiveness: a special focus on nivolumab and pembrolizumab · Ruben Malmberg · 2022 · 97 citations · Cited by this paper
  22. Resting Metabolic Rate and Body Composition of Achondroplastic Dwarfs · Oliver E. Owen · 1990 · 69 citations · Cited by this paper
  23. Sensitive inductively coupled plasma mass spectrometry assay for the determination of platinum originating from cisplatin, carboplatin, and oxaliplatin in human plasma ultrafiltrate · Elke E. M. Brouwers · 2006 · 63 citations · Cited by this paper
  24. The use of the Calvert formula to determine the optimal carboplatin dosage · Laurence J. C. van Warmerdam · 1995 · 58 citations · Cited by this paper
  25. Flat Dosing of Carboplatin Is Justified in Adult Patients with Normal Renal Function · Corine Ekhart · 2006 · 58 citations · Cited by this paper
  26. Clinical application of a semimechanistic-physiologic population PK/PD model for neutropenia following pemetrexed therapy · Jane E. Latz · 2005 · 49 citations · Cited by this paper
  27. Measured versus estimated glomerular filtration rate in the Calvert equation: influence on carboplatin dosing · Angela Donahue · 2001 · 39 citations · Cited by this paper
  28. Mechanisms, Management and Prevention of Pemetrexed-Related Toxicity · Nikki de Rouw · 2021 · 39 citations · Cited by this paper
  29. Estimation of glomerular filtration rate for drug dosing in patients with very high or low body mass index · Erik M. Donker · 2022 · 24 citations · Cited by this paper
  30. Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis · Nikki de Rouw · 2021 · 21 citations · Cited by this paper
  31. Toxicity of pemetrexed during renal impairment explained—Implications for safe treatment · René J. Boosman · 2021 · 20 citations · Cited by this paper
  32. Whole-body and segmental analysis of body composition in adult males with achondroplasia using dual X-ray absorptiometry · David Thomas Sims · 2019 · 18 citations · Cited by this paper
  33. A cost analysis study of the implementation of fixed-dosing of monoclonal antibodies in the Netherlands Cancer Institute · Kimberley M. Heinhuis · 2020 · 14 citations · Cited by this paper
  34. Optimized sample pre-treatment procedure for the simultaneous UPLC-MS/MS quantification of ipilimumab, nivolumab, and pembrolizumab in human serum · Karen A.M. de Jong · 2022 · 11 citations · Cited by this paper
  35. A limited sampling schedule to estimate individual pharmacokinetics of pemetrexed in patients with varying renal functions · Nikki de Rouw · 2019 · 9 citations · Cited by this paper
  36. Simple and Rapid Quantification of the Multi-Enzyme Targeting Antifolate Pemetrexed in Human Plasma · Erik van den Hombergh · 2019 · 7 citations · Cited by this paper
  37. Weight-Based Pembrolizumab Dosing at 4 mg/kg Every 6 Weeks Leads to Exposures Below Approved Doses with Unestablished Efficacy: A Pharmacokinetic Model-Based Simulation Analysis · Mallika Lala · 2025 · 3 citations · Cited by this paper
  38. Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment · Nikki de Rouw · 2025 · 3 citations · Cited by this paper
  39. Chemotherapy dosing in achondroplastic dwarfism: a case report and review of literature · Raymond Elsoueidi · 2016 · 2 citations · Cited by this paper

Source: OpenAlex (CC0)