Research map: Mesenchymal stem cell‐derived exosomes for cardiac repair: Challenges, standardization gaps and a realistic path to clinical translation

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  26. Exosomes Derived from Akt -Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating Platelet-Derived Growth Factor D · Jie Ma · 2016 · 313 citations · Cited by this paper
  27. Exosomes Derived from Human Endothelial Progenitor Cells Accelerate Cutaneous Wound Healing by Promoting Angiogenesis Through Erk1/2 Signaling · Jieyuan Zhang · 2016 · 287 citations · Cited by this paper
  28. Regulation of exosomes as biologic medicines: Regulatory challenges faced in exosome development and manufacturing processes · Chun‐Kai Wang · 2024 · 275 citations · Cited by this paper
  29. The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection · Derek John Hausenloy · 2018 · 266 citations · Cited by this paper
  30. Exosomes in clinical trial and their production in compliance with good manufacturing practice · Horng‐Jyh Harn · 2019 · 249 citations · Cited by this paper
  31. Development of Extracellular Vesicle Therapeutics: Challenges, Considerations, and Opportunities · Bethany Claridge · 2021 · 241 citations · Cited by this paper
  32. Mesenchymal stem cells in treating human diseases: molecular mechanisms and clinical studies · Xia Han · 2025 · 220 citations · Cited by this paper
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  35. Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis · Alexandra N. Nowbar · 2014 · 208 citations · Cited by this paper
  36. Hypoxia-challenged MSC-derived exosomes deliver miR-210 to attenuate post-infarction cardiac apoptosis · Hao Cheng · 2020 · 190 citations · Cited by this paper
  37. Therapeutic Features and Updated Clinical Trials of Mesenchymal Stem Cell (MSC)-Derived Exosomes · Byung‐Chul Lee · 2021 · 189 citations · Cited by this paper
  38. Manufacturing Therapeutic Exosomes: from Bench to Industry · So‐Hee Ahn · 2022 · 189 citations · Cited by this paper
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