Research map: Targeting EGFR Endocytosis and Signaling for Cancer Drug Delivery and Cancer Treatment

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  1. Cell Signaling by Receptor Tyrosine Kinases · Mark A. Lemmon · 2010 · 8020 citations · Cited by this paper
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  13. Epidermal Growth Factor · G Carpenter · 1979 · 2939 citations · Cited by this paper
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  15. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells · Axel Ullrich · 1984 · 2786 citations · Cited by this paper
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  17. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences · Julian Downward · 1984 · 2545 citations · Cited by this paper
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  19. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction · Boudewijn M.T. Burgering · 1995 · 2112 citations · Cited by this paper
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  24. An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor · Xuewu Zhang · 2006 · 1684 citations · Cited by this paper
  25. Epidermal growth factor. · G Carpenter · 1990 · 1627 citations · Cited by this paper
  26. Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor · Jennifer L. Stamos · 2002 · 1585 citations · Cited by this paper
  27. Epidermal growth factor receptor: mechanisms of activation and signalling · Robert N. Jorissen · 2003 · 1567 citations · Cited by this paper
  28. The ErbB/HER family of protein-tyrosine kinases and cancer · Robert Jr. Roskoski · 2013 · 1366 citations · Cited by this paper
  29. Mechanisms and consequences of activation of protein kinase B/Akt · Julian Downward · 1998 · 1313 citations · Cited by this paper
  30. Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes. · Hiroshi Ushiro · 1980 · 1184 citations · Cited by this paper
  31. The origins of protein phosphorylation · Philip Cohen · 2002 · 1163 citations · Cited by this paper
  32. Nuclear localization of EGF receptor and its potential new role as a transcription factor · Shiaw‐Yih Lin · 2001 · 1074 citations · Cited by this paper
  33. The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase · Claudio A.P. Joazeiro · 1999 · 1040 citations · Cited by this paper
  34. The ERBB network: at last, cancer therapy meets systems biology · Yosef Yarden · 2012 · 1026 citations · Cited by this paper
  35. Control of EGF Receptor Signaling by Clathrin-Mediated Endocytosis · Amandio Vincent Vieira · 1996 · 1016 citations · Cited by this paper
  36. Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1 · Gil Levkowitz · 1999 · 1006 citations · Cited by this paper
  37. Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro · Jill Meisenhelder · 1989 · 976 citations · Cited by this paper
  38. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. · Ryo Nishikawa · 1994 · 941 citations · Cited by this paper
  39. Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors · Yong Jia · 2016 · 907 citations · Cited by this paper

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