Research map: Combined anti-PD-1 with irreversible electroporation relieves immunosuppression and reduces hepatocellular carcinoma regrowth

Back to the article

Papers in this map

  1. Hepatocellular carcinoma · Alejandro Forner · 2018 · 5718 citations · Cited by this paper
  2. Second-line practices in the era of immunotherapy in HCC: The CHIEF cohort · 2026 · Related
  3. PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation · Muhammad Zaeem Noman · 2014 · 2214 citations · Cited by this paper
  4. Interleukin-8–driven monocyte activation in primary sclerosing cholangitis: Insights from single-cell analysis and humanized immune system mice · 2026 · Related
  5. Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer · Kai Li · 2021 · 1004 citations · Cited by this paper
  6. A hepatocyte-derived GPNMB–RYK signaling axis in MASH progression · 2026 · Related
  7. The role of m6A RNA methylation in cancer metabolism · Yuanyuan An · 2022 · 907 citations · Cited by this paper
  8. Development and psychometric evaluation of the Liver Disease Stigma Scale (LDSS) · 2026 · Related
  9. In Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity · Martijn H. den Brok · 2004 · 425 citations · Cited by this paper
  10. Global Trends in National Alcohol Control Policies Between 2010–2019 · 2026 · Related
  11. COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells · Mitsugu Fujita · 2011 · 387 citations · Cited by this paper
  12. Is it too early to dismiss corticosteroids in CDK4/6 inhibitor-induced liver injury? · 2026 · Related
  13. Safety and early efficacy of irreversible electroporation for hepatic tumors in proximity to vital structures · Robert M. Cannon · 2012 · 338 citations · Cited by this paper
  14. Peripartum ALT Flares Predict Earlier Postpartum HBeAg Clearance in Highly Viremic HBV-Infected Women: A Long-term Follow-up Study · 2026 · Related
  15. Therapeutic targeting of tumour myeloid cells · Simon T. Barry · 2023 · 303 citations · Cited by this paper
  16. The Use of FGF21 Analogues in MASH and MASH Cirrhosis – Metabolic Master Regulators or Liver-Specific Mechanisms? ☆ · 2026 · Related
  17. How chemokines organize the tumour microenvironment · Thorsten R. Mempel · 2023 · 281 citations · Cited by this paper
  18. Hepatic flares, their immune signatures, and ALT variability after nucleos(t)ide analogue cessation in HBeAg-negative hepatitis B · 2026 · Related
  19. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer · Jun Zhao · 2019 · 278 citations · Cited by this paper
  20. Changes in alcohol use following a diagnosis of alcohol-related liver disease: a clinical cohort study · 2026 · Related
  21. LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity · Lawrence Peter Andrews · 2024 · 277 citations · Cited by this paper
  22. Enhancement of tumor-associated antigen-specific T cell responses by radiofrequency ablation of hepatocellular carcinoma · Eishiro Mizukoshi · 2012 · 274 citations · Cited by this paper
  23. Radiofrequency Ablation Induces Antigen-presenting Cell Infiltration and Amplification of Weak Tumor-induced Immunity · Sergio A. Dromi · 2009 · 231 citations · Cited by this paper
  24. Aggressive Intrasegmental Recurrence of Hepatocellular Carcinoma after Radiofrequency Ablation: Risk Factors and Clinical Significance · Tae Wook Kang · 2015 · 139 citations · Cited by this paper
  25. Release of endogenous danger signals from HIFU-treated tumor cells and their stimulatory effects on APCs · Zhenlin Hu · 2005 · 121 citations · Cited by this paper
  26. Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells · Brandon J. Burbach · 2021 · 93 citations · Cited by this paper
  27. The progress of immune checkpoint therapy in primary liver cancer · Yi-Min Zheng · 2021 · 86 citations · Cited by this paper
  28. Irreversible electroporation induces CD8+ T cell immune response against post-ablation hepatocellular carcinoma growth · Zihao Dai · 2021 · 81 citations · Cited by this paper
  29. Profiling of syngeneic mouse HCC tumor models as a framework to understand anti–PD‐1 sensitive tumor microenvironments · Daniel J. Zabransky · 2022 · 65 citations · Cited by this paper
  30. Radiofrequency Ablation Remodels the Tumor Microenvironment and Promotes Neutrophil-Mediated Abscopal Immunomodulation in Pancreatic Cancer · Erika Yanil Faraoni · 2022 · 65 citations · Cited by this paper
  31. Safety and Short-Term Efficacy of Irreversible Electroporation and Allogenic Natural Killer Cell Immunotherapy Combination in the Treatment of Patients with Unresectable Primary Liver Cancer · Yu-Mei Yang · 2018 · 58 citations · Cited by this paper
  32. Dynamic changes of T-cell subsets and their relation with tumor recurrence after microwave ablation in patients with hepatocellular carcinoma · Yan Zhou · 2018 · 47 citations · Cited by this paper
  33. Short-term clinical efficacy of percutaneous irreversible electroporation combined with allogeneic natural killer cell for treating metastatic pancreatic cancer · Mao Lin · 2017 · 40 citations · Cited by this paper
  34. Immunogenic Cell Death in Electroporation-Based Therapies Depends on Pulse Waveform Characteristics · Tamara Polajžer · 2023 · 35 citations · Cited by this paper
  35. YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment · Zhenyun Yang · 2024 · 33 citations · Cited by this paper
  36. Systemic injection of TLR1/2 agonist improves adoptive antigen-specific T cell therapy in glioma-bearing mice · Yufei Zhang · 2014 · 30 citations · Cited by this paper
  37. Systemic Effects of Local Tumor Ablation: Oncogenesis and Antitumor Induced Immunity · Giovanni Mauri · 2016 · 10 citations · Cited by this paper
  38. How Biology Guides the Combination of Locoregional Interventional Therapies and Immunotherapy for Hepatocellular Carcinoma: Cytokines and Their Roles · Yan Fu · 2023 · 6 citations · Cited by this paper
  39. cGAS-STING activation mediated by FAM83H-AS1/HMGB1 elicits NF-κB-dependent immune evasion in breast cancer · Zhi-Mei Liang · 2025 · 2 citations · Cited by this paper

Source: OpenAlex (CC0)