Research map: Managing Acute Severe Ulcerative Colitis in 2025 and Beyond

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Papers in this map

  1. ACG Clinical Guideline: Ulcerative Colitis in Adults · David T. Rubin · 2019 · 1611 citations · Cited by this paper
  2. Lowering the C‐Reactive Protein ( CRP ) Threshold Improves Risk Stratification in Acute Ulcerative Colitis: A Propensity‐Matched Analysis · Amirah Etchegaray · 2026 · 4 citations · Cites this paper
  3. Traction Techniques for Endoscopic Submucosal Dissection (ESD): Organ-Specific Best Practices and Western Outcomes · Emmanuel Palomera-Tejeda · 2025 · 2 citations · Related
  4. Predicting outcome in severe ulcerative colitis. · Simon P.L. Travis · 1996 · 793 citations · Cited by this paper
  5. ECCO Guidelines on Therapeutics in Ulcerative Colitis: Surgical Treatment · Michel Adamina · 2026 · 2 citations · Cites this paper
  6. Small Bowel Bleeding Due to Vascular Lesions: Pathogenesis and Management · 2025 · Related
  7. Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial · David Laharie · 2012 · 652 citations · Cited by this paper
  8. Frontiers in the management of acute severe ulcerative colitis: current best practice and future directions · Richard Hall · 2026 · Cites this paper
  9. The Impact of Specialized Pro-Resolving Mediators on Disease Activity and the Risk of Associated Colorectal Carcinoma in Inflammatory Bowel Disease · 2025 · Related
  10. Excess hospitalisation burden associated with Clostridium difficile in patients with inflammatory bowel disease · Aparnaa Ananthakrishnan · 2007 · 425 citations · Cited by this paper
  11. Navigating Treatment Selection in Acute Severe Ulcerative Colitis: A Prospective Mixed Method Analysis of Factors Influencing Patient Decision-Making · Reid M. Herran · 2026 · Cites this paper
  12. Intestinal Ultrasound for Monitoring Colonic Inflammation in Inflammatory Bowel Disease · 2025 · Related
  13. Infliximab versus ciclosporin for steroid-resistant acute severe ulcerative colitis (CONSTRUCT): a mixed methods, open-label, pragmatic randomised trial · John Gordon Williams · 2016 · 270 citations · Cited by this paper
  14. Early Predictors of Steroid Failure in Acute Severe Ulcerative Colitis: A Retrospective Study With the Evaluation of the Admission Model for Intensification of Therapy in Acute Severe Colitis (ADMIT-ASC) Score · Othmane Merzouki · 2026 · Cites this paper
  15. Pediatric Culinary Medicine: Current Status, Challenges and Opportunities · 2025 · Related
  16. Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis · Jian Chen Fang · 2021 · 266 citations · Cited by this paper
  17. Colon-targeted mucin/cyclosporine A co-loaded microspheres synergistically ameliorate ulcerative colitis via immunosuppression and mucosal barrier repair · Lei Qian · 2026 · Cites this paper
  18. Underwater Endoscopic Submucosal Dissection: Tips and Tricks · 2026 · Related
  19. Severe Pediatric Ulcerative Colitis: A Prospective Multicenter Study of Outcomes and Predictors of Response · Dan Turner · 2010 · 258 citations · Cited by this paper
  20. Documento de posicionamiento del Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (GETECCU) sobre el diagnóstico y manejo de la colitis ulcerosa aguda grave · Íngrid Ordás · 2026 · Cites this paper
  21. Guselkumab plus golimumab combination therapy versus guselkumab or golimumab monotherapy in patients with ulcerative colitis (VEGA): a randomised, double-blind, controlled, phase 2, proof-of-concept trial · Brian G. Feagan · 2023 · 242 citations · Cited by this paper
  22. Editorial: Advances in the treatment of acute severe ulcerative colitis · Hirannya Karunadasa · 2026 · Cites this paper
  23. Acute severe ulcerative colitis: from pathophysiology to clinical management · Pieter Hindryckx · 2016 · 191 citations · Cited by this paper
  24. ACG Clinical Guideline Update: Ulcerative Colitis in Adults · David T. Rubin · 2025 · 183 citations · Cited by this paper
  25. Epidemiology of Inflammatory Bowel Disease across the Ages in the Era of Advanced Therapies · Bénédicte Caron · 2024 · 152 citations · Cited by this paper
  26. Tofacitinib for Biologic-Experienced Hospitalized Patients With Acute Severe Ulcerative Colitis: A Retrospective Case-Control Study · Jeffrey Aaron Berinstein · 2021 · 140 citations · Cited by this paper
  27. Real-world Effectiveness of Tofacitinib for Moderate to Severe Ulcerative Colitis: A Multicentre UK Experience · Sailish Honap · 2020 · 125 citations · Cited by this paper
  28. Tofacitinib in Acute Severe Ulcerative Colitis (TACOS): A Randomized Controlled Trial · Arshdeep Singh · 2023 · 112 citations · Cited by this paper
  29. CRP/Albumin Ratio · David J Gibson · 2017 · 99 citations · Cited by this paper
  30. Acute severe ulcerative colitis trials: the past, the present and the future · Sailish Honap · 2024 · 76 citations · Cited by this paper
  31. Tofacitinib for Acute Severe Ulcerative Colitis: A Systematic Review · Casper Steenholdt · 2023 · 71 citations · Cited by this paper
  32. Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial · Matthew C. Choy · 2024 · 63 citations · Cited by this paper
  33. Effectiveness of Upadacitinib for Patients With Acute Severe Ulcerative Colitis: A Multicenter Experience · Jeffrey Aaron Berinstein · 2024 · 54 citations · Cited by this paper
  34. The Role of the Microbiome in the Pathogenesis and Treatment of Ulcerative Colitis—A Literature Review · Gabriela Świrkosz · 2023 · 47 citations · Cited by this paper
  35. Top-down infliximab plus azathioprine versus azathioprine alone in patients with acute severe ulcerative colitis responsive to intravenous steroids: a parallel, open-label randomised controlled trial, the ACTIVE trial · Aurélien Amiot · 2024 · 25 citations · Cited by this paper
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