Research map: Quantitative systems pharmacology of HIV PrEP and PEP

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  1. Exact stochastic simulation of coupled chemical reactions · Daniel T. Gillespie · 1977 · 10742 citations · Cited by this paper
  2. Tirabrutinib–anthracycline interactions in the brain tumor microenvironment: a focus on metabolic inactivation and resistance · 2025 · Related
  3. HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time · Alan S. Perelson · 1996 · 3593 citations · Cited by this paper
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  7. Viral Load and Heterosexual Transmission of Human Immunodeficiency Virus Type 1 · Thomas C. Quinn · 2000 · 3082 citations · Cited by this paper
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  9. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy · Diana Finzi · 1999 · 2171 citations · Cited by this paper
  10. Pharmacokinetics and safety of the combination of KL130008 and methotrexate in rheumatoid arthritis patients: a multicenter, open-label phase Ib trial · 2025 · Related
  11. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection · Tae‐Wook Chun · 1997 · 2095 citations · Cited by this paper
  12. Evaluation of the drug-drug interaction between low-dose methotrexate and short-term use of non-steroidal anti-inflammatory drugs · 2025 · Related
  13. The Theory of Branching Processes · Theodore E. Harris · 1963 · 2053 citations · Cited by this paper
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  15. Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana · Michael C. Thigpen · 2012 · 2040 citations · Cited by this paper
  16. Modifying Hy’s Law and eDISH for the modern idiosyncratic DILI era · 2025 · Related
  17. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection · Brandon F. Keele · 2008 · 1969 citations · Cited by this paper
  18. T cell immunity is key to the pandemic endgame: How to measure and monitor it · 2022 · Related
  19. Approximate accelerated stochastic simulation of chemically reacting systems · Daniel T. Gillespie · 2001 · 1963 citations · Cited by this paper
  20. Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long‐Acting Lenacapavir Pre‐Exposure Prophylaxis ( PrEP ) Against HIV · 2026 · Related
  21. Decay characteristics of HIV-1-infected compartments during combination therapy · Alan S. Perelson · 1997 · 1922 citations · Cited by this paper
  22. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells · Janet D'Angelo Siliciano · 2003 · 1770 citations · Cited by this paper
  23. On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection · Jean‐Michel Molina · 2015 · 1670 citations · Cited by this paper
  24. Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure · Ya‐Chi Ho · 2013 · 1501 citations · Cited by this paper
  25. Dynamics of HIV viremia and antibody seroconversion in plasma donors · Eberhard W. Fiebig · 2003 · 1331 citations · Cited by this paper
  26. Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women · Jeanne Marisa Marrazzo · 2015 · 1315 citations · Cited by this paper
  27. A Case–Control Study of HIV Seroconversion in Health Care Workers after Percutaneous Exposure · Denise M. Cardo · 1997 · 1217 citations · Cited by this paper
  28. �ber die analytischen Methoden in der Wahrscheinlichkeitsrechnung · Andrey Kolmogoroff · 1931 · 1085 citations · Cited by this paper
  29. Sexual Transmission of HIV · Rachel A. Royce · 1997 · 1074 citations · Cited by this paper
  30. Dynamics of HIV infection of CD4+ T cells · Alan S. Perelson · 1993 · 995 citations · Cited by this paper
  31. Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies · Marie‐Claude Boily · 2009 · 925 citations · Cited by this paper
  32. Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women · Raphael J. Landovitz · 2021 · 916 citations · Cited by this paper
  33. The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery · Dennis A. Smith · 2010 · 904 citations · Cited by this paper
  34. The immune response during acute HIV-1 infection: clues for vaccine development · Andrew James McMichael · 2009 · 873 citations · Cited by this paper
  35. Estimating per-act HIV transmission risk · Pragna Patel · 2014 · 770 citations · Cited by this paper
  36. Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys · James B. Whitney · 2014 · 651 citations · Cited by this paper
  37. Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial · Sinéad Delany‐Moretlwe · 2022 · 593 citations · Cited by this paper
  38. Targeting early infection to prevent HIV-1 mucosal transmission · Ashley T. Haase · 2010 · 592 citations · Cited by this paper
  39. Estimating the proportion of HIV transmissions from main sex partners among men who have sex with men in five US cities · Patrick S. Sullivan · 2009 · 571 citations · Cited by this paper

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