Research map: Bowel Regeneration: Bench to Bedside

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Papers in this map

  1. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche · Toshiro Sato · 2009 · 7384 citations · Cited by this paper
  2. Neuro-immune-bone axis in post-traumatic bone regeneration: temporal regulation, dysregulation mechanisms, and therapeutic implications · Zhonghua Wang · 2026 · Cites this paper
  3. A novel dynamic in-vitro model of esophageal button battery ingestion demonstrating benefits of honey, but not acetic acid · 2026 · Related
  4. Identification of stem cells in small intestine and colon by marker gene Lgr5 · Nick Barker · 2007 · 5829 citations · Cited by this paper
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  6. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro · Jason R. Spence · 2010 · 1976 citations · Cited by this paper
  7. How to build an adolescent bariatric surgery program · 2026 · Related
  8. The Intestinal Crypt, A Prototype Stem Cell Compartment · Hans C. Clevers · 2013 · 1248 citations · Cited by this paper
  9. Lessons in leadership from military-informed pediatric surgeons · 2026 · Related
  10. The Continuing Importance of Bile Acids in Liver and Intestinal Disease · Alan Frederick Hofmann · 1999 · 994 citations · Cited by this paper
  11. Infections in pediatric surgical practice in low- and middle-income countries: Resource-adapted clinical decision-making · 2026 · Related
  12. Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell · Shiro Yui · 2012 · 817 citations · Cited by this paper
  13. Regenerative Medicine in Pediatric Surgery · 2026 · Related
  14. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis · Mikhail Yu. Nikolaev · 2020 · 770 citations · Cited by this paper
  15. Extracellular vesicles in perinatal conditions: A minimally invasive approach to regenerative medicine · 2026 · Related
  16. ESPEN guidelines on chronic intestinal failure in adults · Loris Pironi · 2016 · 720 citations · Cited by this paper
  17. Appendicitis as a model for pediatric surgical quality improvement and standardization · 2026 · Related
  18. Selective cell transplantation using bioabsorbable artificial polymers as matrices · Joseph P. Vacanti · 1988 · 606 citations · Cited by this paper
  19. Quick clots for tiny spots: Hemostatic agents in action · 2026 · Related
  20. Short Bowel Syndrome and Intestinal Failure: Consensus Definitions and Overview · Stephen J. O’Keefe · 2006 · 520 citations · Cited by this paper
  21. Effects of caudal versus penile block on the incidence of hypospadias complications following primary repairs: A prospective, double-blind, randomized controlled trial · 2025 · Related
  22. Teduglutide Reduces Need for Parenteral Support Among Patients With Short Bowel Syndrome With Intestinal Failure · Palle Bekker Jeppesen · 2012 · 505 citations · Cited by this paper
  23. Intestinal loop lengthening—A technique for increasing small intestinal length · Adrian Bianchi · 1980 · 485 citations · Cited by this paper
  24. Natural History of Pediatric Intestinal Failure: Initial Report from the Pediatric Intestinal Failure Consortium · Robert H. Squires · 2012 · 466 citations · Cited by this paper
  25. Serial transverse enteroplasty (STEP): A novel bowel lengthening procedure · Heung Bae Kim · 2003 · 418 citations · Cited by this paper
  26. Pediatric Short Bowel Syndrome · Ariel U. Spencer · 2005 · 333 citations · Cited by this paper
  27. Improved survival in a multidisciplinary short bowel syndrome program · Biren P. Modi · 2008 · 226 citations · Cited by this paper
  28. Tissue-Engineered Small Intestine Improves Recovery After Massive Small Bowel Resection · Tracy C. Grikscheit · 2004 · 223 citations · Cited by this paper
  29. A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration · Giorgia Totonelli · 2012 · 214 citations · Cited by this paper
  30. Understanding short bowel syndrome: Current status and future perspectives · Sara Massironi · 2019 · 197 citations · Cited by this paper
  31. Short bowel syndrome: epidemiology and etiology · Paul William Wales · 2009 · 187 citations · Cited by this paper
  32. An organoid-based organ-repurposing approach to treat short bowel syndrome · Shinya Sugimoto · 2021 · 175 citations · Cited by this paper
  33. Tissue-Engineered Small Intestine and Stomach Form from Autologous Tissue in a Preclinical Large Animal Model · Frédéric Sala · 2009 · 162 citations · Cited by this paper
  34. Safety and Efficacy of Teduglutide in Pediatric Patients With Intestinal Failure due to Short Bowel Syndrome: A 24‐Week, Phase III Study · Samuel A. Kocoshis · 2019 · 158 citations · Cited by this paper
  35. Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure · Laween Meran · 2020 · 143 citations · Cited by this paper
  36. Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function · Christa N. Grant · 2015 · 100 citations · Cited by this paper
  37. Predicting Intestinal Adaptation in Pediatric Intestinal Failure · Christina Belza · 2017 · 94 citations · Cited by this paper
  38. Gut hormones, and short bowel syndrome: The enigmatic role of glucagon-like peptide-2 in the regulation of intestinal adaptation · GR Martin · 2006 · 77 citations · Cited by this paper
  39. SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling · Wei Yong Gu · 2021 · 74 citations · Cited by this paper

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