Research map: Effects of combination metformin and nintedanib therapy in a mouse model of irradiation-induced pulmonary fibrosis

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  1. TGF-β: the master regulator of fibrosis · Xiao‐Ming Meng · 2016 · 3605 citations · Cited by this paper
  2. DVH parameters and gastrointestinal/genitourinary toxicities in moderate hypofractionated salvage radiotherapy after radical prostatectomy · 2026 · Related
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  15. Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis · Vahid Kheirollahi · 2019 · 305 citations · Cited by this paper
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  17. Efficacy of antifibrotic drugs, nintedanib and pirfenidone, in treatment of progressive pulmonary fibrosis in both idiopathic pulmonary fibrosis (IPF) and non-IPF: a systematic review and meta-analysis · James Patrick Finnerty · 2021 · 215 citations · Cited by this paper
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  19. Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling · Xiaohua Yan · 2011 · 212 citations · Cited by this paper
  20. Comorbidities in idiopathic pulmonary fibrosis: an underestimated issue · Antonella Caminati · 2019 · 140 citations · Cited by this paper
  21. TGF-β : Titan of Lung Fibrogenesis · Xinping Yue · 2010 · 131 citations · Cited by this paper
  22. Combine and conquer: advantages and disadvantages of fixed‐dose combination therapy · David S.H. Bell · 2012 · 113 citations · Cited by this paper
  23. Prediction of Cancer Incidence and Mortality in Korea, 2021 · Kyu‐Won Jung · 2021 · 99 citations · Cited by this paper
  24. Effectiveness of combined therapy with pirfenidone and inhaled N ‐acetylcysteine for advanced idiopathic pulmonary fibrosis: A case–control study · Susumu Sakamoto · 2015 · 90 citations · Cited by this paper
  25. Recent Trends of Lung Cancer in Korea · Jae Guk Lee · 2021 · 64 citations · Cited by this paper
  26. Surfactant Protein D Protects against Acute Hyperoxic Lung Injury · Deepika Kumari Jain · 2008 · 57 citations · Cited by this paper
  27. Scarred Lung. An Update on Radiation-Induced Pulmonary Fibrosis · Natalia Jarzebska · 2021 · 54 citations · Cited by this paper
  28. Surfactant protein D attenuates acute lung and kidney injuries in pneumonia-induced sepsis through modulating apoptosis, inflammation and NF-κB signaling · Juan Du · 2018 · 53 citations · Cited by this paper
  29. Identification of molecular signatures involved in radiation-induced lung fibrosis · Hee Kyung Jin · 2018 · 46 citations · Cited by this paper
  30. Surfactant protein D inhibits lipid-laden foamy macrophages and lung inflammation in chronic obstructive pulmonary disease · Miao-Hsi Hsieh · 2022 · 43 citations · Cited by this paper
  31. Idiopathic pulmonary fibrosis: Current knowledge, future perspectives and its importance in radiation oncology · Görkem Türkkan · 2020 · 39 citations · Cited by this paper
  32. Protective effects of metformin on lipopolysaccharide‑induced airway epithelial cell injury via NF‑κB signaling inhibition · Jiayang Sun · 2019 · 31 citations · Cited by this paper
  33. Anti irradiation nanoparticles shelter immune organ from radio-damage via preventing the IKK/IκB/NF-κB activation · Shigao Huang · 2024 · 30 citations · Cited by this paper
  34. Efficacy and safety of combination therapy with pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis · Jin-Young Huh · 2023 · 23 citations · Cited by this paper
  35. Pirfenidone and nintedanib attenuate pulmonary fibrosis in mice by inhibiting the expression of JAK2 · Yan Yang · 2024 · 14 citations · Cited by this paper
  36. Evidence that metformin promotes fibrosis resolution via activating alveolar epithelial stem cells and FGFR2b signaling · Yuqing Lv · 2025 · 6 citations · Cited by this paper
  37. Novel synergistic therapeutic approach in idiopathic pulmonary fibrosis: Combining the antifibrotic nintedanib with the anti-inflammatory baricitinib · Qin Wan · 2025 · 5 citations · Cited by this paper
  38. Combined treatment of tacrolimus and pirfenidone effectively improves BLM-induced pulmonary fibrosis in mice by inhibiting the TGFβ1/Smad2/3 signaling · Ying Li · 2025 · 3 citations · Cited by this paper

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