Research map: Myeloperoxidase (MPO) inhibitors: an updated patent review (2020 - present)

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Papers in this map

  1. Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker · Peter P. Bradley · 1982 · 3641 citations · Cited by this paper
  2. Sirtuin modulators: a review of patents from 2020 to 2024 · 2025 · Related
  3. Nitric oxide synthases: structure, function and inhibition · Wendy K. ALDERTON · 2001 · 3542 citations · Cited by this paper
  4. A patent review of Mpro protease inhibitors for the treatment of COVID-19 infections (2020 – present) · 2025 · Related
  5. Structure and Chemistry of Cytochrome P450 · Ilia G. Denisov · 2005 · 2104 citations · Cited by this paper
  6. Therapeutic applications of benzoxaborole compounds: a patent and literature analysis (2019–2024) · 2025 · Related
  7. Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species · Ken‐ichi Setsukinai · 2003 · 1300 citations · Cited by this paper
  8. An updated patent review of histone deacetylase 6 inhibitors in neurodegenerative diseases (2020–2025) · 2026 · Related
  9. Myeloperoxidase and Cardiovascular Disease · Stephen James Nicholls · 2005 · 802 citations · Cited by this paper
  10. 5’-Ectonucleotidase (CD73) inhibitors: a patent review (2021-present) · 2026 · Related
  11. Nitric Oxide and Endothelial Dysfunction · Anthony Roger Cyr · 2020 · 646 citations · Cited by this paper
  12. PCSK9 inhibitors: an updated patent review 2024–2025 · 2026 · Related
  13. X-ray Crystal Structure and Characterization of Halide-binding Sites of Human Myeloperoxidase at 1.8 Å Resolution · Tristan J. Fiedler · 2000 · 376 citations · Cited by this paper
  14. Topoisomerase II inhibitors in oncology: an updated patent review (2016-present) · 2025 · Related
  15. Active site structure and catalytic mechanisms of human peroxidases · Paul Georg Furtmüller · 2005 · 357 citations · Cited by this paper
  16. Recent advances in the discovery of PKMYT1-targeting drugs: a patent review (2021–2025) · 2026 · Related
  17. NETosis markers: Quest for specific, objective, and quantitative markers · Sakiko Masuda · 2016 · 296 citations · Cited by this paper
  18. Implementation and outcomes of China’s drug patent linkage system: lessons from international experience · 2025 · Related
  19. Reaction of Myeloperoxidase Compound I with Chloride, Bromide, Iodide, and Thiocyanate · Paul Georg Furtmüller · 1998 · 294 citations · Cited by this paper
  20. An updated patent review of acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease (2021–present) · 2025 · Related
  21. Independent evolution of four heme peroxidase superfamilies · Marcel Zámocký · 2015 · 252 citations · Cited by this paper
  22. The Roles of Neutrophil-Derived Myeloperoxidase (MPO) in Diseases: The New Progress · Wei Chen Lin · 2024 · 245 citations · Cited by this paper
  23. Myeloperoxidase: A new player in autoimmunity · Anna Strzępa · 2017 · 235 citations · Cited by this paper
  24. Nitric Oxide Modulates the Catalytic Activity of Myeloperoxidase · Husam M. Abu‐Soud · 2000 · 197 citations · Cited by this paper
  25. Inhibition of myeloperoxidase by benzoic acid hydrazides · Anthony James Kettle · 1995 · 185 citations · Cited by this paper
  26. Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase · Paula M. Bozeman · 1990 · 171 citations · Cited by this paper
  27. 2-Thioxanthines Are Mechanism-based Inactivators of Myeloperoxidase That Block Oxidative Stress during Inflammation · A.K. Tiden · 2011 · 163 citations · Cited by this paper
  28. The Dual Role of Myeloperoxidase in Immune Response · Jürgen Arnhold · 2020 · 158 citations · Cited by this paper
  29. Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies · Dawid Dębski · 2016 · 155 citations · Cited by this paper
  30. Spectral and Kinetic Studies on the Formation of Myeloperoxidase Compounds I and II: Roles of Hydrogen Peroxide and Superoxide · Leah A. Marquez‐Curtis · 1994 · 135 citations · Cited by this paper
  31. Role of myeloperoxidase in inflammation and atherosclerosis (Review) · Christian Frangie · 2022 · 118 citations · Cited by this paper
  32. Melatonin Is a Potent Inhibitor for Myeloperoxidase · Semira Galijašević · 2008 · 112 citations · Cited by this paper
  33. Myeloperoxidase Inhibition Ameliorates Multiple System Atrophy-Like Degeneration in a Transgenic Mouse Model · Nadia Stefanova · 2011 · 111 citations · Cited by this paper
  34. Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates · Louisa V. Forbes · 2013 · 106 citations · Cited by this paper
  35. MPO (Myeloperoxidase) Reduces Endothelial Glycocalyx Thickness Dependent on Its Cationic Charge · Kashish Manchanda · 2018 · 97 citations · Cited by this paper
  36. Myeloperoxidase and Neurological Disorder: A Crosstalk · Kanta Pravalika · 2018 · 92 citations · Cited by this paper
  37. Exploitation of the unusual thermodynamic properties of human myeloperoxidase in inhibitor design · Walter Jantschko · 2005 · 85 citations · Cited by this paper
  38. 8-Substituted O6-Benzylguanine, Substituted 6(4)-(Benzyloxy)pyrimidine, and Related Derivatives as Inactivators of Human O6-Alkylguanine-DNA Alkyltransferase · Mi-Young Chae · 1995 · 78 citations · Cited by this paper
  39. The development of myeloperoxidase inhibitors · Semira Galijašević · 2018 · 73 citations · Cited by this paper

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