Research map: Immune profiling by bulk RNA-seq and multiplex immunofluorescence imaging across multiple cancer types

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Papers in this map

  1. Robust enumeration of cell subsets from tissue expression profiles · Aaron M. Newman · 2015 · 14504 citations · Cited by this paper
  2. Contrast-enhanced ultrasound-guided biopsy and perfusion monitoring for bladder involvement in relapsed multiple myeloma: a case report · 2026 · Related
  3. Inferring tumour purity and stromal and immune cell admixture from expression data · Kosuke Yoshihara · 2013 · 10961 citations · Cited by this paper
  4. Ferroptosis in multiple myeloma: molecular mechanisms and therapeutic opportunities · 2026 · Related
  5. Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome · Jérôme Galon · 2006 · 6644 citations · Cited by this paper
  6. Adaptive dosing of immunotherapy plus anti-angiogenic therapy in a nonagenarian with hepatocellular carcinoma: a case report with 10-year survival · 2026 · Related
  7. TIMER2.0 for analysis of tumor-infiltrating immune cells · Taiwen Li · 2020 · 5797 citations · Cited by this paper
  8. Predictors and prevalence of lateral supraclavicular lymph node metastases on [18F]FDG PET/CT in patients with locally advanced, or multifocal invasive ductal carcinoma of breast: potential impact on adjuvant radiotherapy targets · 2026 · Related
  9. The tumor microenvironment · Nicole M. Anderson · 2020 · 2743 citations · Cited by this paper
  10. Case Report: a hypermetabolic mediastinal mass (SUVmax 16.7) mimicking malignancy with spontaneous resolution: an inflammatory myofibroblastic proliferation and diagnostic pitfall · 2026 · Related
  11. The immune contexture in cancer prognosis and treatment · Wolf H. Fridman · 2017 · 2375 citations · Cited by this paper
  12. Variations in histopathological and molecular subtypes between primary breast carcinoma and associated liver metastatic lesions · 2026 · Related
  13. Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry · Charlotte Giesen · 2014 · 2074 citations · Cited by this paper
  14. Concurrent icotinib and definitive radiotherapy followed by detection of an EGFR exon 20 insertion at disease progression in unresectable stage III EGFR S768I-mutant lung adenocarcinoma: a case report · 2026 · Related
  15. Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer · Luis Alfonso Rojas · 2023 · 1407 citations · Cited by this paper
  16. Perioperative outcomes and prognostic determinants in adult spindle cell/sclerosing rhabdomyosarcoma: implications of treatment intensity, surgical margins, and molecular heterogeneity · 2026 · Related
  17. Systematic pan-cancer analysis of tumour purity · Dvir Aran · 2015 · 1345 citations · Cited by this paper
  18. The combined compartmental maxillary resection: technique codification and preliminary multicenter series analysis · 2026 · Related
  19. Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma · Jason Alan Chesney · 2017 · 635 citations · Cited by this paper
  20. Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis · Takahiro Tsujikawa · 2017 · 620 citations · Cited by this paper
  21. Prognostic Value of Tumor-Infiltrating CD4+ T-Cell Subpopulations in Head and Neck Cancers · Cécile Badoual · 2006 · 610 citations · Cited by this paper
  22. Tumor Microenvironment Dynamics in Clear-Cell Renal Cell Carcinoma · Lynda H. Vuong · 2019 · 488 citations · Cited by this paper
  23. Dual Effect of Immune Cells within Tumour Microenvironment: Pro- and Anti-Tumour Effects and Their Triggers · Alicia Cristina Peña-Romero · 2022 · 261 citations · Cited by this paper
  24. Colorectal Cancer Metastases in the Liver Establish Immunosuppressive Spatial Networking between Tumor-Associated SPP1 + Macrophages and Fibroblasts · Anuja Sathe · 2022 · 208 citations · Cited by this paper
  25. The Prognostic Importance of CD20+ B lymphocytes in Colorectal Cancer and the Relation to Other Immune Cell subsets · Sofia Edin · 2019 · 156 citations · Cited by this paper
  26. High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers · Grace L. Banik · 2019 · 92 citations · Cited by this paper
  27. Combination of dual immune checkpoint inhibition (ICI) with stereotactic radiation (SBRT) in metastatic renal cell carcinoma (mRCC) (RADVAX RCC). · Hans J. Hammers · 2020 · 88 citations · Cited by this paper
  28. Prognostic Significance of Immune Cell Populations Identified by Machine Learning in Colorectal Cancer Using Routine Hematoxylin and Eosin–Stained Sections · Juha P. Väyrynen · 2020 · 88 citations · Cited by this paper
  29. Pan-cancer classification of single cells in the tumour microenvironment · Ido Nofech-Mozes · 2023 · 84 citations · Cited by this paper
  30. RNA Sequencing in Comparison to Immunohistochemistry for Measuring Cancer Biomarkers in Breast Cancer and Lung Cancer Specimens · Maxim Sorokin · 2020 · 69 citations · Cited by this paper
  31. Prognostic value of the common tumour-infiltrating lymphocyte subtypes for patients with non-small cell lung cancer: A meta-analysis · Benchao Chen · 2020 · 63 citations · Cited by this paper
  32. Immune profiling and prognostic model of pancreatic cancer using quantitative pathology and single-cell RNA sequencing · Kai Chen · 2023 · 63 citations · Cited by this paper
  33. Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment · Juha P. Väyrynen · 2021 · 50 citations · Cited by this paper
  34. Modulation of the tumour microenvironment in hepatocellular carcinoma by tyrosine kinase inhibitors: from modulation to combination therapy targeting the microenvironment · Ruyin Chen · 2022 · 49 citations · Cited by this paper
  35. The role of T-cells in head and neck squamous cell carcinoma: From immunity to immunotherapy · Marcos Paulo S. Damasio · 2022 · 43 citations · Cited by this paper
  36. Understanding the dynamics of TKI-induced changes in the tumor immune microenvironment for improved therapeutic effect · Conghua Lu · 2024 · 42 citations · Cited by this paper
  37. Single-cell sequencing on CD8+ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer · Hiroyasu Komuro · 2023 · 41 citations · Cited by this paper
  38. Characterization of immune microenvironment in patients with HPV-positive and negative head and neck cancer · Zhongqiu Wang · 2023 · 36 citations · Cited by this paper
  39. Differential gene expression of tumor-infiltrating CD8 + T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis · Reem Saleh · 2020 · 35 citations · Cited by this paper

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