Research map: Programmable CAR and antigen pairing for solid tumor immunotherapy
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Papers in this map
CAR-T cell therapy: current limitations and potential strategies
· Robert C. Sterner · 2021 · 2926 citations · Cited by this paper
CAR design equips diverse immune cells with unique antigen-specific activation identities
· Ayano Sugiyama-Finnis · 2026 · Related
Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma
· Eugenia Zah · 2020 · 233 citations · Cited by this paper
Rethinking lymphodepleting preconditioning in adoptive T cell therapy for durable tumor control
· 2026 · Related
Enhancing the safety of CAR-T cell therapy: Synthetic genetic switch for spatiotemporal control
· Li Lu · 2024 · 108 citations · Cited by this paper
Depletion of IL-10 in CAR-NK cells augments reprogramming of the tumor microenvironment and ameliorates therapeutic efficacy
· 2026 · Related
A rational mouse model to detect on-target, off-tumor CAR T cell toxicity
· Mauro L. Castellarin · 2020 · 105 citations · Cited by this paper
AGTR1 signaling contributes to tumor immunity and therapy response in non-small cell lung cancer
· 2026 · Related
An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics
· Molly E. Allen · 2019 · 46 citations · Cited by this paper
CART-immune-related adverse events after BCMA CAR-T therapy
· 2026 · Related
Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface
· Praopim Limsakul · 2018 · 30 citations · Cited by this paper
Unmasking Wnt-driven HCC: Inhibiting SMYD2 to overcome immune resistance
· 2026 · Related
Optogenetic Control for Investigating Subcellular Localization of Fyn Kinase Activity in Single Live Cells
· Ziliang Huang · 2020 · 7 citations · Cited by this paper
Intraperitoneal delivery of the oncolytic virus CF17 improves tumor immunogenicity and survival in gastric cancer peritoneal metastasis
· 2026 · Related
AI-driven cellular immunotherapy: transforming CAR-T engineering and translation
· Ziliang Huang · 2026 · 2 citations · Cited by this paper
Synergistic Cell-Cycle Repression by HDAC/EZH2 Co-Targeting in H3K27-Altered Diffuse Midline Glioma
· 2026 · Related
CD19 antigen: From tumor target to safety switch able to improve the safety profile of CAR T cell therapy
· Simona Manni · 2025 · 1 citation · Cited by this paper
Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicity
· 2026 · Related
Optimizing CAR T cell therapy in pancreatic cancer through clinically actionable combinations
· 2026 · Related
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