Research map: A Sequential Gut–Pancreas–Liver In Vitro Model to Evaluate the Multi-Target Metabolic Effects of a Nutraceutical Formulation in MASLD-Related Conditions

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  1. The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review · Zobair M. Younossi · 2023 · 3310 citations · Cited by this paper
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  21. Diacylglycerol Activation of Protein Kinase Cε and Hepatic Insulin Resistance · François R. Jornayvaz · 2012 · 314 citations · Cited by this paper
  22. Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia · Xue Li · 2017 · 314 citations · Cited by this paper
  23. Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products · Dinali H. Fernando · 2019 · 191 citations · Cited by this paper
  24. Pathogenesis of MASLD and MASH – role of insulin resistance and lipotoxicity · Shalini Bansal · 2024 · 171 citations · Cited by this paper
  25. The Caco-2 Model: Modifications and enhancements to improve efficiency and predictive performance · Nimishraj Panse · 2022 · 130 citations · Cited by this paper
  26. Non-alcoholic fatty liver disease and childhood obesity · Meera Shaunak · 2020 · 128 citations · Cited by this paper
  27. Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells · Melissa F. Brereton · 2016 · 125 citations · Cited by this paper
  28. NAFLD/MASLD and the Gut–Liver Axis: From Pathogenesis to Treatment Options · Natalia G. Vallianou · 2024 · 90 citations · Cited by this paper
  29. Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy · Peter Mullen · 2009 · 88 citations · Cited by this paper
  30. Inflammation in Obesity-Related Complications in Children: The Protective Effect of Diet and Its Potential Role as a Therapeutic Agent · Valeria Calcaterra · 2020 · 86 citations · Cited by this paper
  31. Reappraisal of Adipose Tissue Inflammation in Obesity · Atilla Engin · 2024 · 70 citations · Cited by this paper
  32. Evaluation of the toxicity of sodium dodecyl sulphate (SDS) in the MucilAir™ human airway model in vitro · Jonathan Welch · 2021 · 68 citations · Cited by this paper
  33. Medicinal plants and bioactive natural compounds as inhibitors of HMG‐CoA reductase: A literature review · Atena Mahdavi · 2020 · 67 citations · Cited by this paper
  34. In vitro studies of adhesion properties of six lactic acid bacteria isolated from the longevous population of China · Chengran Guan · 2020 · 52 citations · Cited by this paper
  35. Silymarin attenuated nonalcoholic fatty liver disease through the regulation of endoplasmic reticulum stress proteins GRP78 and XBP-1 in mice · Erhan Şahin · 2020 · 48 citations · Cited by this paper
  36. Transport of Dietary Anti-Inflammatory Peptide, γ-Glutamyl Valine (γ-EV), across the Intestinal Caco-2 Monolayer · Snigdha Guha · 2021 · 48 citations · Cited by this paper
  37. EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion · Bruno Blanchi · 2023 · 46 citations · Cited by this paper
  38. Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): the interplay of gut microbiome, insulin resistance, and diabetes · Ankita Dua · 2025 · 43 citations · Cited by this paper
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