Research map: Metformin alleviates paraquat-induced pulmonary fibrosis by promoting caveolin-1 and inhibiting ferroptosis

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  1. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death · Scott J. Dixon · 2012 · 19067 citations · Cited by this paper
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  13. Unsolved mysteries: How does lipid peroxidation cause ferroptosis? · Huizhong Feng · 2018 · 777 citations · Cited by this paper
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  15. Metformin reverses established lung fibrosis in a bleomycin model · Sunad Rangarajan · 2018 · 595 citations · Cited by this paper
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  17. Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis · Harold A. Chapman · 2011 · 421 citations · Cited by this paper
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  19. Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis · Xiao Mei Wang · 2006 · 398 citations · Cited by this paper
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  21. Inhibition of ferroptosis and iron accumulation alleviates pulmonary fibrosis in a bleomycin model · Zhuo Pei · 2022 · 271 citations · Cited by this paper
  22. AMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice · Yachun Han · 2021 · 269 citations · Cited by this paper
  23. Paraquat poisoning: clinical features and immediate general management · Allister Vale · 1987 · 240 citations · Cited by this paper
  24. Metformin attenuates silica-induced pulmonary fibrosis via AMPK signaling · Demin Cheng · 2021 · 142 citations · Cited by this paper
  25. Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis · Haipeng Cheng · 2021 · 133 citations · Cited by this paper
  26. A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase‐2 in idiopathic pulmonary fibrosis · William R. Coward · 2014 · 120 citations · Cited by this paper
  27. Role of caveolin-1 in fibrotic diseases · David Gvaramia · 2013 · 120 citations · Cited by this paper
  28. Isoliquiritigenin alleviates liver fibrosis through caveolin-1-mediated hepatic stellate cells ferroptosis in zebrafish and mice · Sha Huang · 2022 · 97 citations · Cited by this paper
  29. Oxidative stress-mediated alterations in histone post-translational modifications · Jose Luis García‐Giménez · 2021 · 75 citations · Cited by this paper
  30. Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)–Dependent Pulmonary Arterial Hypertension · Suellen D. Oliveira · 2019 · 63 citations · Cited by this paper
  31. Paraquat Induces Epithelial-Mesenchymal Transition-Like Cellular Response Resulting in Fibrogenesis and the Prevention of Apoptosis in Human Pulmonary Epithelial Cells · Atsushi Yamada · 2015 · 53 citations · Cited by this paper
  32. Triptolide suppresses paraquat induced idiopathic pulmonary fibrosis by inhibiting TGFB1-dependent epithelial mesenchymal transition · Hong Chen · 2017 · 51 citations · Cited by this paper
  33. Where ferroptosis inhibitors and paraquat detoxification mechanisms intersect, exploring possible treatment strategies · Niloofar Rashidipour · 2020 · 45 citations · Cited by this paper
  34. An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury · Huy Quang Le · 2021 · 40 citations · Cited by this paper
  35. Caveolin‐1 negatively regulates inflammation and fibrosis in silicosis · Rongling He · 2021 · 38 citations · Cited by this paper
  36. Regulation of NCOA4-mediated iron recycling ameliorates paraquat-induced lung injury by inhibiting ferroptosis · Jing Du · 2024 · 33 citations · Cited by this paper
  37. Metformin attenuates fibroblast activation during pulmonary fibrosis by targeting S100A4 via AMPK-STAT3 axis · Hui-min Ji · 2023 · 24 citations · Cited by this paper
  38. Research progress of metformin in the treatment of liver fibrosis · Anqi Zhang · 2023 · 23 citations · Cited by this paper
  39. Caveolin-1 as a critical component in the pathogenesis of lung fibrosis of different etiology: Evidences and mechanisms · Ritu Kulshrestha · 2019 · 22 citations · Cited by this paper

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