Research map: Peptide exchange–competent class I MHC molecules produced in eukaryotic cells for rapid production of MHC multimers

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  1. Phenotypic Analysis of Antigen-Specific T Lymphocytes · John D. Altman · 1996 · 3587 citations · Cited by this paper
  2. Extracellular vesicles and cytokines released from Pseudomonas aeruginosa infected macrophages activate cardiac fibroblasts 2259917 · 2026 · Related
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  5. Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid. · P H Hirel · 1989 · 770 citations · Cited by this paper
  6. The Indigestible Burden of Microplastics Drives Bioenergetic Dysfunction in Macrophages 2260413 · 2026 · Related
  7. HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides. · David N. Garboczi · 1992 · 707 citations · Cited by this paper
  8. HuR—SerpinB9 Axis Regulates Tumor T-Cell Fitness and Persistence via Post-Transcriptional Control 2267776 · 2026 · Related
  9. Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N -acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line · Philip J. Reeves · 2002 · 652 citations · Cited by this paper
  10. MicroRNA-1246 regulates macrophage lipid metabolism and is involved in resistance to human Mycobacterium tuberculosis infection 2259565 · 2026 · Related
  11. E unum pluribus: multiple proteins from a self-processing polyprotein · Pablo de Felipe · 2005 · 371 citations · Cited by this paper
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  13. Design and use of conditional MHC class I ligands · Mireille Toebes · 2006 · 357 citations · Cited by this paper
  14. A 61-Parameter CyTOF Panel for Comprehensive Profiling of Human PBMC to Characterize Activation, Differentiation, Checkpoints and Cytokines 2259198 · 2026 · Related
  15. Production of soluble MHC class II proteins with covalently bound single peptides · Haruo Kozono · 1994 · 310 citations · Cited by this paper
  16. Characterizing the role of ovarian hormones in regulating sex differences in baseline immune parameters 2309498 · 2026 · Related
  17. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers · Cheryl L. Day · 2003 · 258 citations · Cited by this paper
  18. High throughput CRISPR screens reveals novel roles for retroviral elements in proliferation and inflammation in murine macrophages 2259338 · 2026 · Related
  19. Development of a Candidate HLA A*0201 Restricted Peptide-Based Vaccine Against Human Cytomegalovirus Infection · Don J. Diamond · 1997 · 250 citations · Cited by this paper
  20. Bivalent vaccination fails to enhance conserved spike T cell responses across BetaCoronaviruses 2260452 · 2026 · Related
  21. Substrate requirements of human rhinovirus 3C protease for peptide cleavage in vitro. · Michael G. Cordingley · 1990 · 211 citations · Cited by this paper
  22. Fluorescence Polarization (FP) Assays for Monitoring Peptide‐Protein or Nucleic Acid‐Protein Binding · Nathan J. Moerke · 2009 · 194 citations · Cited by this paper
  23. A general method for facilitating heterodimeric pairing between two proteins: application to expression of alpha and beta T-cell receptor extracellular segments. · H C Chang · 1994 · 151 citations · Cited by this paper
  24. Cutting Edge: Single-Chain Trimers of MHC Class I Molecules Form Stable Structures That Potently Stimulate Antigen-Specific T Cells and B Cells · Yik Y. L. Yu · 2002 · 139 citations · Cited by this paper
  25. One-Pot, Mix-and-Read Peptide-MHC Tetramers · Christian Leisner · 2008 · 99 citations · Cited by this paper
  26. Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells · Sunil Kumar Saini · 2019 · 99 citations · Cited by this paper
  27. Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules. · C A Scott · 1996 · 92 citations · Cited by this paper
  28. Immunization of mice with vaccinia virus-M2 recombinant induces epitope-specific and cross-reactive Kd-restricted CD8+ cytotoxic T cells · Arun B. Kulkarni · 1993 · 87 citations · Cited by this paper
  29. The Signal Sequence of Lymphocytic Choriomeningitis Virus Contains an Immunodominant Cytotoxic T Cell Epitope That Is Restricted by both H-2Dband H-2KbMolecules · Denis Hudrisier · 1997 · 87 citations · Cited by this paper
  30. Structural Engineering of pMHC Reagents for T Cell Vaccines and Diagnostics · Vesselin Mitaksov · 2007 · 63 citations · Cited by this paper
  31. Dipeptides catalyze rapid peptide exchange on MHC class I molecules · Sunil Kumar Saini · 2014 · 57 citations · Cited by this paper
  32. A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells · Jolien J. Luimstra · 2018 · 51 citations · Cited by this paper
  33. Peptide–β2-microglobulin–MHC fusion molecules bind antigen-specific T cells and can be used for multivalent MHC–Ig complexes · Tim F. Greten · 2002 · 48 citations · Cited by this paper
  34. Real-Time Measurement of in Vitro Peptide Binding to Soluble HLA-A*0201 by Fluorescence Polarization · Rico Buchli · 2004 · 42 citations · Cited by this paper
  35. In vivo biotinylation of the major histocompatibility complex (MHC) class II/peptide complex by coexpression of BirA enzyme for the generation of MHC class II/tetramers · Junbao Yang · 2004 · 42 citations · Cited by this paper
  36. Soluble Class I MHC with β2-Microglobulin Covalently Linked Peptides: Specific Binding to a T Cell Hybridoma · Janice White · 1999 · 42 citations · Cited by this paper
  37. Reversible Major Histocompatibility Complex I-Peptide Multimers Containing Ni2+-Nitrilotriacetic Acid Peptides and Histidine Tags Improve Analysis and Sorting of CD8+ T Cells · Julien Schmidt · 2011 · 36 citations · Cited by this paper
  38. Empty conformers of HLA-B preferentially bind CD8 and regulate CD8+ T cell function · Jie Geng · 2018 · 32 citations · Cited by this paper
  39. Preparation of Stable Single‐Chain Trimers Engineered with Peptide, β2 Microglobulin, and MHC Heavy Chain · Ted H. Hansen · 2009 · 31 citations · Cited by this paper

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